Comparative evaluation of liver, spleen, and kidney stiffness in HIV-monoinfected pediatric patients via shear wave elastography

Emine ÇALIŞKAN; Gürkan ATAY; Manolya KARA; Murat SÜTÇÜ; Zuhal BAYRAMOĞLU; Selda Hançerli TÖRÜN; Ayper SOMER; İbrahim ADALETLİ

Makale detayları

Comparative evaluation of liver, spleen, and kidney stiffness in HIV-monoinfected pediatric patients via shear wave elastography

Yazarlar:

Emine ÇALIŞKAN | Gürkan ATAY | Manolya KARA | Murat SÜTÇÜ | Zuhal BAYRAMOĞLU | Selda Hançerli TÖRÜN | Ayper SOMER | İbrahim ADALETLİ

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 2019 Vol.49 Issue 3, pp.899-906

Belge Tipi:

Makale

Yayın Tarihi:

5/2019

Belge Dili:

İngilizce

Document ID (Org No.):

2000750131

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144

Özet:

 

Background/aim: This study aimed to evaluate the stiffness of the liver, spleen, and kidneys in HIV-monoinfected children via shear wave elastography (SWE).Materials and methods: Twenty-one HIV-monoinfected children and 37 healthy subjects were included in this study. Livers, spleens, and kidneys of the participants were examined via ultrasound and SWE. Patients were divided into two groups according to the presence of pathologic ultrasonographic findings. Routine laboratory tests were also recorded. Stiffness of these organs was compared between patients and control groups.Results:  Liver  transaminases,  blood  urea,  and  creatinine  levels  were  normal  in  all  subjects.  Ultrasonographic  examination  revealed  hepatosplenomegaly (n = 1, 4.7%), grade 1 hepatosteatosis (n = 1, 4.7%), and hepatosteatosis and minimal heterogeneity of the liver (n = 1, 4.7%). Ultrasonographic features were normal in 18 patients. Stiffness of the liver, spleen, and kidneys of all HIV-monoinfected children with normal laboratory parameters was significantly higher than in healthy subjects. Eighteen patients with normal ultrasonographic findings also had higher stiffness values when compared to control subjects.  Conclusion: Stiffness of the liver, spleen, and kidneys in HIV-monoinfected children was increased. SWE can be used in the detection of early parenchymal changes even in patients with normal laboratory parameters and ultrasonographic findings.

Makale detayları

Comparative evaluation of liver, spleen, and kidney stiffness in HIV-monoinfected pediatric patients via shear wave elastography

Yazarlar: Emine ÇALIŞKAN | Gürkan ATAY | Manolya KARA | Murat SÜTÇÜ | Zuhal BAYRAMOĞLU | Selda Hançerli TÖRÜN | Ayper SOMER | İbrahim ADALETLİ

Yayıncı: TUBITAK

Dergi: Turkish Journal of Medical Sciences 2019 Vol.49 Issue 3, pp.899-906

Belge Tipi: Makale

Yayın Tarihi: 5/2019

Belge Dili: İngilizce

Document ID (Org No.): 2000750131

Sıklık: İki Aylık

eISSN: 1303-6165

pISSN: 1300-0144

Sayı

Yazarlar:

Emine ÇALIŞKAN | Gürkan ATAY | Manolya KARA | Murat SÜTÇÜ | Zuhal BAYRAMOĞLU | Selda Hançerli TÖRÜN | Ayper SOMER | İbrahim ADALETLİ

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 2019 Vol.49 Issue 3, pp.899-906

Belge Tipi:

Makale

Yayın Tarihi:

5/2019

Belge Dili:

İngilizce

Document ID (Org No.):

2000750131

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144