Scalpel Versus Electrocautery Dissections: The Effect on Wound Complications and Pro-Inflammatory Cytokine Levels in Wound Fluid

Mehmet ÖZDOĞAN

Makale detayları

Scalpel Versus Electrocautery Dissections: The Effect on Wound Complications and Pro-Inflammatory Cytokine Levels in Wound Fluid

Yazarlar:

Mehmet ÖZDOĞAN

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 2008 Vol.38 Issue 2, pp.111-116

Belge Tipi:

Makale

Yayın Tarihi:

1/2008

Belge Dili:

Türkçe

Document ID (Org No.):

2000755839

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144

Anahtar kelimeler:

Özet:

 

Aim: Electrocautery has been postulated as a risk factor for wound complications. This study was conducted to evaluate the effects of electrocautery and scalpel dissections on wound complications and local cytokine levels.   Materials and Methods: Patients undergoing modified radical mastectomy were assigned to flap dissection with either electrocautery (n = 18) or scalpel (n = 20). Blood loss, drain volume and duration, seroma formation and wound complications were recorded. Tumor necrosis factor-alpha (TNF-a) and interleukin (IL)-6 levels were measured in drain fluids at postoperative 24 hours.   Results: The electrocautery group had significantly reduced blood loss and total drain volume, but increased seroma formation rate. Significantly elevated levels of TNF-aa were measured in drain fluids of patients with electrocautery dissection.   Conclusions: The use of electrocautery causes less bleeding and total drain output with an increased rate of seroma formation. Electrocautery dissection increases pro-inflammatory cytokine response in wound fluid, which may reflect an aggravated inflammation and increased potential for tissue damage.

 

Aim: Electrocautery has been postulated as a risk factor for wound complications. This study was conducted to evaluate the effects of electrocautery and scalpel dissections on wound complications and local cytokine levels.   Materials and Methods: Patients undergoing modified radical mastectomy were assigned to flap dissection with either electrocautery (n = 18) or scalpel (n = 20). Blood loss, drain volume and duration, seroma formation and wound complications were recorded. Tumor necrosis factor-alpha (TNF-a) and interleukin (IL)-6 levels were measured in drain fluids at postoperative 24 hours.   Results: The electrocautery group had significantly reduced blood loss and total drain volume, but increased seroma formation rate. Significantly elevated levels of TNF-aa were measured in drain fluids of patients with electrocautery dissection.   Conclusions: The use of electrocautery causes less bleeding and total drain output with an increased rate of seroma formation. Electrocautery dissection increases pro-inflammatory cytokine response in wound fluid, which may reflect an aggravated inflammation and increased potential for tissue damage.

Makale detayları

Scalpel Versus Electrocautery Dissections: The Effect on Wound Complications and Pro-Inflammatory Cytokine Levels in Wound Fluid

Yazarlar:

Mehmet ÖZDOĞAN

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 2008 Vol.38 Issue 2, pp.111-116

Belge Tipi:

Makale

Yayın Tarihi:

1/2008

Belge Dili:

Türkçe

Document ID (Org No.):

2000755839

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144

Electrocautery

sharp dissection

seroma

wound complication

tumor necrosis factor-alpha

interleukin-6

Sayı

Makale detayları

Scalpel Versus Electrocautery Dissections: The Effect on Wound Complications and Pro-Inflammatory Cytokine Levels in Wound Fluid

Yazarlar: Mehmet ÖZDOĞAN

Yayıncı: TUBITAK

Dergi: Turkish Journal of Medical Sciences 2008 Vol.38 Issue 2, pp.111-116

Belge Tipi: Makale

Yayın Tarihi: 1/2008

Belge Dili: Türkçe

Document ID (Org No.): 2000755839

Sıklık: İki Aylık

eISSN: 1303-6165

pISSN: 1300-0144

Electrocautery

sharp dissection

seroma

wound complication

tumor necrosis factor-alpha

interleukin-6

Sayı

Yazarlar:

Mehmet ÖZDOĞAN

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 2008 Vol.38 Issue 2, pp.111-116

Belge Tipi:

Makale

Yayın Tarihi:

1/2008

Belge Dili:

Türkçe

Document ID (Org No.):

2000755839

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144