Effects of Ketogenic and Western Diets on Proliferation, Vasculogenesis and Oxidative Stress in the Liver

Songül DOĞANAY; Özcan BUDAK; Nurten BAHTİYAR; Veysel TOPRAK

Makale detayları

Effects of Ketogenic and Western Diets on Proliferation, Vasculogenesis and Oxidative Stress in the Liver

Yazarlar:

Songül DOĞANAY | Özcan BUDAK | Nurten BAHTİYAR | Veysel TOPRAK

Yayıncı:

Ondokuz Mayıs University

Ana Başlıklar:

Sağlık teşvikleri

Dergi:

Journal of Experimental and Clinical Medicine 2021 Vol.38 Issue 3, pp.312-317

Belge Tipi:

Makale

Yayın Tarihi:

4/2021

Belge Dili:

İngilizce

Document ID (Org No.):

2000507501

Sıklık:

Üç Aylık

eISSN:

1309-5129

pISSN:

1309-4483

Özet:

 

Objective: In this study, it was aimed to investigate the effects of different diets on lipid peroxidation, antioxidants, proliferation and vasculogenesis in liver tissue.
Materials and Methods: BALBC female rats (21) were divided as the group fed with standard chow (SC), the group fed with a ketogenic diet (KD) and the group fed with western diet (WD). The rats were fed with tap water and a rat diet specially prepared according to the determined diets for 4 weeks. Liver tissue oxidative damage, proliferation and vasculogenesis were evaluated using spectrophotometric and immunohistopathological methods. 
Results: At the end of the experiment, it was found that the highest weight gain was in the WD group and the least weight gain was in the KD group. The mean body weight of the WD group was statistically significantly higher compared to the SC and KD groups (p0.05). 
Conclusion: These results revealed that ketogenic diet prevents tissue damage by decreasing lipid peroxidation in liver tissue as well as inducing cellular proliferation and vasculogenesis.

Makale detayları

Effects of Ketogenic and Western Diets on Proliferation, Vasculogenesis and Oxidative Stress in the Liver

Yazarlar: Songül DOĞANAY | Özcan BUDAK | Nurten BAHTİYAR | Veysel TOPRAK

Yayıncı: Ondokuz Mayıs University

Ana Başlıklar: Sağlık teşvikleri

Dergi: Journal of Experimental and Clinical Medicine 2021 Vol.38 Issue 3, pp.312-317

Belge Tipi: Makale

Yayın Tarihi: 4/2021

Belge Dili: İngilizce

Document ID (Org No.): 2000507501

Sıklık: Üç Aylık

eISSN: 1309-5129

pISSN: 1309-4483

Sayı

Yazarlar:

Songül DOĞANAY | Özcan BUDAK | Nurten BAHTİYAR | Veysel TOPRAK

Yayıncı:

Ondokuz Mayıs University

Ana Başlıklar:

Sağlık teşvikleri

Dergi:

Journal of Experimental and Clinical Medicine 2021 Vol.38 Issue 3, pp.312-317

Belge Tipi:

Makale

Yayın Tarihi:

4/2021

Belge Dili:

İngilizce

Document ID (Org No.):

2000507501

Sıklık:

Üç Aylık

eISSN:

1309-5129

pISSN:

1309-4483