Antioxidant and Antibacterial Activities of Salen-type Schiﬀ Base and Metal Complexes

Sezer Göycıncık; Hatice Danahaliloğlu

Makale detayları

Antioxidant and Antibacterial Activities of Salen-type Schiﬀ Base and Metal Complexes

Yazarlar:

Sezer Göycıncık | Hatice Danahaliloğlu

Yayıncı:

Bitlis Eren University

Dergi:

Bitlis Eren Üniversitesi Fen Bilimleri Dergisi Vol.12 Issue 2, pp.329-336

Belge Tipi:

Makale

Yayın Tarihi:

6/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001292719

pISSN:

2147-3129

Anahtar kelimeler:

Özet:

 2-Aminobenzylamine based unsymmetrical salen type Schiﬀ base and its CuII, NiII,CoII and FeIII metal complexes were researched in terms of their antioxidant and antibacterial activities in this study. 1,1-Diphenyl-2-picrylhydrazyl radical scavenging DPPH method, ferric reducing antioxidant power FRAP method and cupric reducing antioxidant capacity CUPRAC method were carried out for determination of antioxidant effects of compounds. The antioxidant activity of the compounds were compared with the standard antioxidants butylated hydroxyanisole BHA and butylated hydroxytoluene BHT. Fe, Ni and Cu complexes exhibited more scavenging activity than BHT. All compounds exhibit lower ferric reducing activity than BHA and BHT. Fe complex, Ni complex and the ligand have more antioxidant capacity than corresponding to BHT according to CUPRAC method. These assays showed that all compounds researched can use as synthetic antioxidants. Antibacterial effects of Schiﬀ base and its metal complexes were investigated by agar disc diffusion method. Antibacterial studies of the compounds were achieved against some gram-positive and gram-negative bacteria. Enterococcus faecium, Pseudomonas aeroginosa, Klebsiella pneumoniae and Escherichia coli were used as bacterial strains. The beneficial datas were acquired.

 2-Aminobenzylamine based unsymmetrical salen type Schiﬀ base and its CuII, NiII,CoII and FeIII metal complexes were researched in terms of their antioxidant and antibacterial activities in this study. 1,1-Diphenyl-2-picrylhydrazyl radical scavenging DPPH method, ferric reducing antioxidant power FRAP method and cupric reducing antioxidant capacity CUPRAC method were carried out for determination of antioxidant effects of compounds. The antioxidant activity of the compounds were compared with the standard antioxidants butylated hydroxyanisole BHA and butylated hydroxytoluene BHT. Fe, Ni and Cu complexes exhibited more scavenging activity than BHT. All compounds exhibit lower ferric reducing activity than BHA and BHT. Fe complex, Ni complex and the ligand have more antioxidant capacity than corresponding to BHT according to CUPRAC method. These assays showed that all compounds researched can use as synthetic antioxidants. Antibacterial effects of Schiﬀ base and its metal complexes were investigated by agar disc diffusion method. Antibacterial studies of the compounds were achieved against some gram-positive and gram-negative bacteria. Enterococcus faecium, Pseudomonas aeroginosa, Klebsiella pneumoniae and Escherichia coli were used as bacterial strains. The beneficial datas were acquired.

 2-Aminobenzylamine based unsymmetrical salen type Schiﬀ base and its CuII, NiII,CoII and FeIII metal complexes were researched in terms of their antioxidant and antibacterial activities in this study. 1,1-Diphenyl-2-picrylhydrazyl radical scavenging DPPH method, ferric reducing antioxidant power FRAP method and cupric reducing antioxidant capacity CUPRAC method were carried out for determination of antioxidant effects of compounds. The antioxidant activity of the compounds were compared with the standard antioxidants butylated hydroxyanisole BHA and butylated hydroxytoluene BHT. Fe, Ni and Cu complexes exhibited more scavenging activity than BHT. All compounds exhibit lower ferric reducing activity than BHA and BHT. Fe complex, Ni complex and the ligand have more antioxidant capacity than corresponding to BHT according to CUPRAC method. These assays showed that all compounds researched can use as synthetic antioxidants. Antibacterial effects of Schiﬀ base and its metal complexes were investigated by agar disc diffusion method. Antibacterial studies of the compounds were achieved against some gram-positive and gram-negative bacteria. Enterococcus faecium, Pseudomonas aeroginosa, Klebsiella pneumoniae and Escherichia coli were used as bacterial strains. The beneficial datas were acquired.

 2-Aminobenzylamine based unsymmetrical salen type Schiﬀ base and its CuII, NiII,CoII and FeIII metal complexes were researched in terms of their antioxidant and antibacterial activities in this study. 1,1-Diphenyl-2-picrylhydrazyl radical scavenging DPPH method, ferric reducing antioxidant power FRAP method and cupric reducing antioxidant capacity CUPRAC method were carried out for determination of antioxidant effects of compounds. The antioxidant activity of the compounds were compared with the standard antioxidants butylated hydroxyanisole BHA and butylated hydroxytoluene BHT. Fe, Ni and Cu complexes exhibited more scavenging activity than BHT. All compounds exhibit lower ferric reducing activity than BHA and BHT. Fe complex, Ni complex and the ligand have more antioxidant capacity than corresponding to BHT according to CUPRAC method. These assays showed that all compounds researched can use as synthetic antioxidants. Antibacterial effects of Schiﬀ base and its metal complexes were investigated by agar disc diffusion method. Antibacterial studies of the compounds were achieved against some gram-positive and gram-negative bacteria. Enterococcus faecium, Pseudomonas aeroginosa, Klebsiella pneumoniae and Escherichia coli were used as bacterial strains. The beneficial datas were acquired.

Makale detayları

Antioxidant and Antibacterial Activities of Salen-type Schiﬀ Base and Metal Complexes

Yazarlar:

Sezer Göycıncık | Hatice Danahaliloğlu

Yayıncı:

Bitlis Eren University

Dergi:

Bitlis Eren Üniversitesi Fen Bilimleri Dergisi Vol.12 Issue 2, pp.329-336

Belge Tipi:

Makale

Yayın Tarihi:

6/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001292719

pISSN:

2147-3129

Salen-type Schiﬀ base

Metal complexes

FRAP

DPPH

CUPRAC

Antibacterial activity

Sayı

Makale detayları

Antioxidant and Antibacterial Activities of Salen-type Schiﬀ Base and Metal Complexes

Yazarlar: Sezer Göycıncık | Hatice Danahaliloğlu

Yayıncı: Bitlis Eren University

Dergi: Bitlis Eren Üniversitesi Fen Bilimleri Dergisi Vol.12 Issue 2, pp.329-336

Belge Tipi: Makale

Yayın Tarihi: 6/2023

Belge Dili: İngilizce

Document ID (Org No.): 2001292719

pISSN: 2147-3129

Salen-type Schiﬀ base

Metal complexes

FRAP

DPPH

CUPRAC

Antibacterial activity

Sayı

Yazarlar:

Sezer Göycıncık | Hatice Danahaliloğlu

Yayıncı:

Bitlis Eren University

Dergi:

Bitlis Eren Üniversitesi Fen Bilimleri Dergisi Vol.12 Issue 2, pp.329-336

Belge Tipi:

Makale

Yayın Tarihi:

6/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001292719

pISSN:

2147-3129