Effect of tumor size on survival in pN0M0 non-small cell lung cancer patients

Gökhan KOCAMAN; Cabir YÜKSEL; Bülent Mustafa YENİGÜN; Mehmet Ali SAKALLI; Durdu KARASOY; Murat ÖZKAN; Serkan ENÖN; Ayten KAYI CANGIR

Makale detayları

Effect of tumor size on survival in pN0M0 non-small cell lung cancer patients

Yazarlar:

Gökhan KOCAMAN | Cabir YÜKSEL | Bülent Mustafa YENİGÜN | Mehmet Ali SAKALLI | Durdu KARASOY | Murat ÖZKAN | Serkan ENÖN | Ayten KAYI CANGIR

Yayıncı:

Turkish Society of Thoracic Surgery

Ana Başlıklar:

Sağlık teşvikleri

Dergi:

CURRENT THORACIC SURGERY 2016 Vol.1 Issue 1, pp.12-15

Belge Tipi:

Makale

Yayın Tarihi:

12/2016

Belge Dili:

Türkçe

Document ID (Org No.):

2000768849

Sıklık:

Üç Yıllık

eISSN:

2548-0316

Özet:

 


Background: Tumor size is one of the major prognostic determinants of non-small cell lung cancer (NSCLC). In the present study, we evaluated the effect of tumor size on survival in pN0M0 NSCLC patients. 

Materials and Methods: Between 1994 and 2013, 1975 NSCLC patients underwent surgery in our center. The study included 774 NSCLC patients with pathological stage N0M0, and these patients were divided into 8 groups according to tumor diameter, as follows, Group 1: 0-10 mm, Group 2: 11-20 mm, Group 3: 21-30 mm, Group 4: 31-40 mm, Group 5: 41-50 mm, Group 6: 51-60 mm, Group 7: 61-70 mm, and Group 8: > 70 mm. We aimed to evaluate the prognostic effect of tumor size on overall survival and to determine a cut-off point for tumor size. 

Results: The 5 year overall survival rate for groups 1 to 8 were 85.6%, 81.3%, 68.6%, 62.2%, 55%, 54.2%, 54.3%, and 45.6%, respectively. The mean follow-up time was 43.8 months. In multivariate analysis, age, tumor size, and surgical resection type had an independent prognostic value on survival. 



Conclusions: Tumor size is an independent prognostic factor for pN0M0 NSCLC patients. A tumor size of 4 cm was found to be the most suitable cut-off point for survival which may be of help in decision-making for adjuvant chemotherapy. 


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Makale detayları

Effect of tumor size on survival in pN0M0 non-small cell lung cancer patients

Yazarlar: Gökhan KOCAMAN | Cabir YÜKSEL | Bülent Mustafa YENİGÜN | Mehmet Ali SAKALLI | Durdu KARASOY | Murat ÖZKAN | Serkan ENÖN | Ayten KAYI CANGIR

Yayıncı: Turkish Society of Thoracic Surgery

Ana Başlıklar: Sağlık teşvikleri

Dergi: CURRENT THORACIC SURGERY 2016 Vol.1 Issue 1, pp.12-15

Belge Tipi: Makale

Yayın Tarihi: 12/2016

Belge Dili: Türkçe

Document ID (Org No.): 2000768849

Sıklık: Üç Yıllık

eISSN: 2548-0316

Sayı

Yazarlar:

Gökhan KOCAMAN | Cabir YÜKSEL | Bülent Mustafa YENİGÜN | Mehmet Ali SAKALLI | Durdu KARASOY | Murat ÖZKAN | Serkan ENÖN | Ayten KAYI CANGIR

Yayıncı:

Turkish Society of Thoracic Surgery

Ana Başlıklar:

Sağlık teşvikleri

Dergi:

CURRENT THORACIC SURGERY 2016 Vol.1 Issue 1, pp.12-15

Belge Tipi:

Makale

Yayın Tarihi:

12/2016

Belge Dili:

Türkçe

Document ID (Org No.):

2000768849

Sıklık:

Üç Yıllık

eISSN:

2548-0316