Evaluation of Oxidative Stress Parameters in Male Textile Workers Working in Different Sections of Production

Leyla Dokumacı; Işıl Yağmur; Rabia Tural; Fatma İnanç Tolun; Hasan Dağlı; Yeliz Doboğlu; Hatice Sağer

Makale detayları

Evaluation of Oxidative Stress Parameters in Male Textile Workers Working in Different Sections of Production

Yazarlar:

Leyla Dokumacı | Işıl Yağmur | Rabia Tural | Fatma İnanç Tolun | Hasan Dağlı | Yeliz Doboğlu | Hatice Sağer

Yayıncı:

Kahramanmaras Sutcu Imam University

Ana Başlıklar:

Sağlık Hizmetleri ve Sistemleri (Diğer)

Dergi:

Kahramanmaraş Sütçü İmam Üniversitesi Tıp Fakültesi Dergisi Vol.19 Issue 3, pp.121-126

Belge Tipi:

Makale

Yayın Tarihi:

4/2024

Belge Dili:

Türkçe

Document ID (Org No.):

2001330136

pISSN:

1303-6610

Anahtar kelimeler:

Özet:

 Objective: Occupationally exposed environmental conditions and many substances threaten human health by causing diseases. This study examines biochemically how the oxidant and antioxidant system parameters change in the employees working in different textile departments. Material and Methods:3 groups of 30 people were formed, each consisting of healthy men who do not smoke or drink alcohol, working in the office, dyehouse and yarn departments of a textile company in Kahramanmaraş office worker control group, group 1, dyehouse worker group 2, yarn worker group 3. After 12 hours of fasting, venous blood samples were taken and serum samples were separated. Total oxidant status TOS, total antioxidant status TAS, total thiol -SH-S-S- TT, and native thiol -SH NT levels were measured spectrophotometrically, oxidative stress index OSI and disulfide -S-S- levels were calculated. Results: There was no significant difference between the groups regarding TOS, TAS, OSI, TT, disulfide, and disulfideNT values p0.05. DisulfideTT levels in the dyehouse group according to the office group, NT and NTTT levels in the yarn group according to the dyehouse group were found to be statistically significantly higher p0.05. Conclusion: It was concluded that it would be beneficial to take necessary precautions against all kinds of exposures that cause oxidative stress in the protection of employee health and to evaluate oxidative stress markers in periodic health screenings of employees.

 Objective: Occupationally exposed environmental conditions and many substances threaten human health by causing diseases. This study examines biochemically how the oxidant and antioxidant system parameters change in the employees working in different textile departments. Material and Methods:3 groups of 30 people were formed, each consisting of healthy men who do not smoke or drink alcohol, working in the office, dyehouse and yarn departments of a textile company in Kahramanmaraş office worker control group, group 1, dyehouse worker group 2, yarn worker group 3. After 12 hours of fasting, venous blood samples were taken and serum samples were separated. Total oxidant status TOS, total antioxidant status TAS, total thiol -SH-S-S- TT, and native thiol -SH NT levels were measured spectrophotometrically, oxidative stress index OSI and disulfide -S-S- levels were calculated. Results: There was no significant difference between the groups regarding TOS, TAS, OSI, TT, disulfide, and disulfideNT values p0.05. DisulfideTT levels in the dyehouse group according to the office group, NT and NTTT levels in the yarn group according to the dyehouse group were found to be statistically significantly higher p0.05. Conclusion: It was concluded that it would be beneficial to take necessary precautions against all kinds of exposures that cause oxidative stress in the protection of employee health and to evaluate oxidative stress markers in periodic health screenings of employees.

 Objective: Occupationally exposed environmental conditions and many substances threaten human health by causing diseases. This study examines biochemically how the oxidant and antioxidant system parameters change in the employees working in different textile departments. Material and Methods:3 groups of 30 people were formed, each consisting of healthy men who do not smoke or drink alcohol, working in the office, dyehouse and yarn departments of a textile company in Kahramanmaraş office worker control group, group 1, dyehouse worker group 2, yarn worker group 3. After 12 hours of fasting, venous blood samples were taken and serum samples were separated. Total oxidant status TOS, total antioxidant status TAS, total thiol -SH-S-S- TT, and native thiol -SH NT levels were measured spectrophotometrically, oxidative stress index OSI and disulfide -S-S- levels were calculated. Results: There was no significant difference between the groups regarding TOS, TAS, OSI, TT, disulfide, and disulfideNT values p0.05. DisulfideTT levels in the dyehouse group according to the office group, NT and NTTT levels in the yarn group according to the dyehouse group were found to be statistically significantly higher p0.05. Conclusion: It was concluded that it would be beneficial to take necessary precautions against all kinds of exposures that cause oxidative stress in the protection of employee health and to evaluate oxidative stress markers in periodic health screenings of employees.

 Amaç: Mesleki olarak maruz kalınan ortam şartları ve birçok madde, hastalıklara neden olarak insan sağlığını tehdit etmektedir. Bu çalışmamızda tekstilde farklı bölümlerde çalışanlarda, oksidan ve antioksidan sistem parametrelerinin nasıl değiştiğinin biyokimyasal olarak incelenmesi amaçlanmıştır. Gereç ve Yöntemler: Kahramanmaraş ilindeki bir tekstil firmasının ofis, boyahane ve iplik bölümlerinde çalışan sigara ya da alkol kullanmayan sağlıklı erkeklerden oluşan 30ar kişilik 3 grup oluşturuldu; ofis çalışanı kontrol grubu, grup 1, boyahane çalışanı grup 2, iplik çalışanı grup 3. 12 saatlik açlığı takiben venöz kan örnekleri alınarak serum örnekleri ayrıldı. Total oksidan durum TOS, total antioksidan durum TAS, total tiyol -SH-S-S- TT ve nativ tiyol -SH NT düzeyleri spektrofotometrik olarak ölçüldü, oksidatif stres indeksi OSİ ve disülfit -S-S- düzeyleri hesaplandı. Bulgular: Gruplar arasında TOS, TAS, OSİ, TT, disülfit ve disülfitNT değerleri açısından anlamlı bir fark yoktu p0.05. Ofis grubuna göre boyahane grubunda disülfitTT düzeyleri, boyahane grubuna göre iplik grubunda NT ve NTTT düzeyleri istatistiksel olarak anlamlı derecede daha yüksek bulundu p0.05. Sonuç: Çalışan sağlığının korunmasında oksidatif strese yol açan her türlü maruziyete karşı gerekli tedbirlerin alınmasının ve çalışanların periyodik sağlık taramalarında oksidatif stres belirteçlerinin de değerlendirilmesinin yararlı olacağı kanaatine varılmıştır.

Makale detayları

Evaluation of Oxidative Stress Parameters in Male Textile Workers Working in Different Sections of Production

Yazarlar:

Leyla Dokumacı | Işıl Yağmur | Rabia Tural | Fatma İnanç Tolun | Hasan Dağlı | Yeliz Doboğlu | Hatice Sağer

Yayıncı:

Kahramanmaras Sutcu Imam University

Ana Başlıklar:

Sağlık Hizmetleri ve Sistemleri (Diğer)

Dergi:

Kahramanmaraş Sütçü İmam Üniversitesi Tıp Fakültesi Dergisi Vol.19 Issue 3, pp.121-126

Belge Tipi:

Makale

Yayın Tarihi:

4/2024

Belge Dili:

Türkçe

Document ID (Org No.):

2001330136

pISSN:

1303-6610

Textile workers

Oxidative stress

Total oxidant level

Total antioxidant level

Thiol/disulfide balanceTekstil çalışanları

Oksidatif stres

Total oksidan seviye

Total antioksidan seviye

Tiyol/disülfid dengesi

Sayı

Makale detayları

Yazarlar: Leyla Dokumacı | Işıl Yağmur | Rabia Tural | Fatma İnanç Tolun | Hasan Dağlı | Yeliz Doboğlu | Hatice Sağer

Yayıncı: Kahramanmaras Sutcu Imam University

Ana Başlıklar: Sağlık Hizmetleri ve Sistemleri (Diğer)

Dergi: Kahramanmaraş Sütçü İmam Üniversitesi Tıp Fakültesi Dergisi Vol.19 Issue 3, pp.121-126

Belge Tipi: Makale

Yayın Tarihi: 4/2024

Belge Dili: Türkçe

Document ID (Org No.): 2001330136

pISSN: 1303-6610

Sayı

Yazarlar:

Leyla Dokumacı | Işıl Yağmur | Rabia Tural | Fatma İnanç Tolun | Hasan Dağlı | Yeliz Doboğlu | Hatice Sağer

Yayıncı:

Kahramanmaras Sutcu Imam University

Ana Başlıklar:

Sağlık Hizmetleri ve Sistemleri (Diğer)

Dergi:

Kahramanmaraş Sütçü İmam Üniversitesi Tıp Fakültesi Dergisi Vol.19 Issue 3, pp.121-126

Belge Tipi:

Makale

Yayın Tarihi:

4/2024

Belge Dili:

Türkçe

Document ID (Org No.):

2001330136

pISSN:

1303-6610