The Ewing’s Sarcoma Family of Tumors of Urinary Bladder: A Case Report and Review of the Literature

Şenol TONYALI; Sertaç YAZICI; Aysun YEŞİLIRMAK; Ali ERGEN

Makale detayları

The Ewing’s Sarcoma Family of Tumors of Urinary Bladder: A Case Report and Review of the Literature

Yazarlar:

Şenol TONYALI | Sertaç YAZICI | Aysun YEŞİLIRMAK | Ali ERGEN

Yayıncı:

Trakya University

Dergi:

Balkan Medical Journal 2016 Vol.33 Issue 4, pp.462-466

Belge Tipi:

Makale

Yayın Tarihi:

6/2016

Belge Dili:

Türkçe

Document ID (Org No.):

2000759513

Sıklık:

İki Aylık

pISSN:

2146-3123

Özet:

 

Background: Only 15 cases of Ewing’s Sarcoma (EWS) family of tumors of urinary bladder have been documented in the literature to date.     Case Report: We presented here a 38 year-old female with primary urinary bladder EWS with no distant metastases. She had presented with macroscopic hematuria and had undergone transurethral resection of the tumor within the following week. Microscopic examination revealed a tumor diffusely infiltrating the lamina propria and muscularis propria under an intact urothelium, which was composed of small round blue cells with scant cytoplasm, monotonous round or oval nuclei, stippled chromatin and small nucleoli. Immunohistochemistry showed strong vimentin, synaptophysin and membranous CD99 expression by the tumor. Fluorescent in situ hybridization analysis displayed the EWSR1 rearrangement. Radical cystectomy with total abdominal hysterectomy and bilateral salpingo-oophorectomy, extended lymph node dissection, and ileal conduit were performed. As adjuvant chemotherapy, she received vincristine, doxorubicin, cyclophosphamide and mesna, alternating with courses of etoposide, iphosphamide and mesna. She is alive and well with no evidence of disease 14 months after the surgery.     Conclusion: Surgery supported with chemotherapy should be considered as an option, especially in advanced Ewing’s sarcoma family of tumors of urinary bladder.

Makale detayları

The Ewing’s Sarcoma Family of Tumors of Urinary Bladder: A Case Report and Review of the Literature

Yazarlar: Şenol TONYALI | Sertaç YAZICI | Aysun YEŞİLIRMAK | Ali ERGEN

Yayıncı: Trakya University

Dergi: Balkan Medical Journal 2016 Vol.33 Issue 4, pp.462-466

Belge Tipi: Makale

Yayın Tarihi: 6/2016

Belge Dili: Türkçe

Document ID (Org No.): 2000759513

Sıklık: İki Aylık

pISSN: 2146-3123

Sayı

Yazarlar:

Şenol TONYALI | Sertaç YAZICI | Aysun YEŞİLIRMAK | Ali ERGEN

Yayıncı:

Trakya University

Dergi:

Balkan Medical Journal 2016 Vol.33 Issue 4, pp.462-466

Belge Tipi:

Makale

Yayın Tarihi:

6/2016

Belge Dili:

Türkçe

Document ID (Org No.):

2000759513

Sıklık:

İki Aylık

pISSN:

2146-3123