Congenital lymphoma of B-cell lineage in a newborn calf

Enver BEYTUT; Burhan ÖZBA

Makale detayları

Congenital lymphoma of B-cell lineage in a newborn calf

Yazarlar:

Enver BEYTUT | Burhan ÖZBA

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Veterinary and Animal Sciences 2012 Vol.36 Issue 1, pp.77-83

Belge Tipi:

Makale

Yayın Tarihi:

12/2011

Belge Dili:

Türkçe

Document ID (Org No.):

2000767054

Sıklık:

İki Aylık

eISSN:

1303-6181

pISSN:

1300-0128

Anahtar kelimeler:

Özet:

 

In this report, congenital lymphoma of B-cell lineage in a Brown Swiss calf is described. A large mass was seen on the head of the calf at birth. At necropsy, multiple masses were found on the skin and internal organs. A histopathological examination showed atypical lymphoid cells separated by connective tissue. None of the tumor cells showed a positive reaction to CD3, but the cells were immunopositive for CD79acy. A CD45+ reaction confirmed a hematopoietic origin of the neoplasm. Tumor cells were also positive for lambda light chain IgG (l IgG). Proliferating cell nuclear antigen (PCNA) immunostaining showed diffuse nuclear positivity. Terminal deoxynucleotidyl transferase mediated dUTP nick end labeling (TUNEL) staining found numerous apoptotic bodies. The neoplasm was diagnosed as a congenital lymphoma of B-cell lineage.

 

In this report, congenital lymphoma of B-cell lineage in a Brown Swiss calf is described. A large mass was seen on the head of the calf at birth. At necropsy, multiple masses were found on the skin and internal organs. A histopathological examination showed atypical lymphoid cells separated by connective tissue. None of the tumor cells showed a positive reaction to CD3, but the cells were immunopositive for CD79acy. A CD45+ reaction confirmed a hematopoietic origin of the neoplasm. Tumor cells were also positive for lambda light chain IgG (l IgG). Proliferating cell nuclear antigen (PCNA) immunostaining showed diffuse nuclear positivity. Terminal deoxynucleotidyl transferase mediated dUTP nick end labeling (TUNEL) staining found numerous apoptotic bodies. The neoplasm was diagnosed as a congenital lymphoma of B-cell lineage.

Makale detayları

Congenital lymphoma of B-cell lineage in a newborn calf

Yazarlar:

Enver BEYTUT | Burhan ÖZBA

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Veterinary and Animal Sciences 2012 Vol.36 Issue 1, pp.77-83

Belge Tipi:

Makale

Yayın Tarihi:

12/2011

Belge Dili:

Türkçe

Document ID (Org No.):

2000767054

Sıklık:

İki Aylık

eISSN:

1303-6181

pISSN:

1300-0128

Key words: B-cell

calf

congenital

lymphoma

Sayı

Makale detayları

Congenital lymphoma of B-cell lineage in a newborn calf

Yazarlar: Enver BEYTUT | Burhan ÖZBA

Yayıncı: TUBITAK

Dergi: Turkish Journal of Veterinary and Animal Sciences 2012 Vol.36 Issue 1, pp.77-83

Belge Tipi: Makale

Yayın Tarihi: 12/2011

Belge Dili: Türkçe

Document ID (Org No.): 2000767054

Sıklık: İki Aylık

eISSN: 1303-6181

pISSN: 1300-0128

Key words: B-cell

calf

congenital

lymphoma

Sayı

Yazarlar:

Enver BEYTUT | Burhan ÖZBA

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Veterinary and Animal Sciences 2012 Vol.36 Issue 1, pp.77-83

Belge Tipi:

Makale

Yayın Tarihi:

12/2011

Belge Dili:

Türkçe

Document ID (Org No.):

2000767054

Sıklık:

İki Aylık

eISSN:

1303-6181

pISSN:

1300-0128