The Effect of Pre-and Postnatal Cd Exposure on  Conduction Velocity in Sciatic Nerve

Piraye YARGIÇOĞLU

Makale detayları

The Effect of Pre-and Postnatal Cd Exposure on Conduction Velocity in Sciatic Nerve

Yazarlar:

Piraye YARGIÇOĞLU

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 1998 Vol.28 Issue 1, pp.47-52

Belge Tipi:

Makale

Yayın Tarihi:

12/1997

Belge Dili:

Türkçe

Document ID (Org No.):

2000758501

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144

Anahtar kelimeler:

Özet:

 

The purpose of the study has been  to investigate the effect of preand postnatal  Cd exposure on conduction velocity of sciatic  nerve.  Pregnant Swiss albino rats were divided into  three groups as control (C), cadmium (Cd)  and non-cadmium (NCd) groups. Control animals  received tap water while rats in Cd  group received Cd as CdCl 2 in their drinking  water during the experimental period. The  mothers of the NCd group were given Cd  during their pregnancy but given tap water  after birth. Twenty-two days after birth  (postnatal day 22) the rats were separated  from the mothers. The present study was  performed on 80 rats which were divided  into C, NCd, Cd 1 and Cd 2 groups, each including 20 rats. Cd 1 group received CdCl 2  water for an additional 8 days. On postnatal  day (PND) 30, conduction velocities and am-plitudes  of compound action potentials were  determined from sciatic nerves of this group.  The other rats were continued to be treated  with Cd (Cd 2 group) or tap water (C and NCd  groups) for an additional 38 days. On PND,  60, the same measurements wer made for  these groups as mentioned above.  The means of the peripheral conduction ve-locities  decreased significanty in all the Cd-treated  groups compared with control group.  The mean of the compound action potential  amplitudes was significantly decreased only in  Cd 2 group compared with control group.

 

The purpose of the study has been  to investigate the effect of preand postnatal  Cd exposure on conduction velocity of sciatic  nerve.  Pregnant Swiss albino rats were divided into  three groups as control (C), cadmium (Cd)  and non-cadmium (NCd) groups. Control animals  received tap water while rats in Cd  group received Cd as CdCl 2 in their drinking  water during the experimental period. The  mothers of the NCd group were given Cd  during their pregnancy but given tap water  after birth. Twenty-two days after birth  (postnatal day 22) the rats were separated  from the mothers. The present study was  performed on 80 rats which were divided  into C, NCd, Cd 1 and Cd 2 groups, each including 20 rats. Cd 1 group received CdCl 2  water for an additional 8 days. On postnatal  day (PND) 30, conduction velocities and am-plitudes  of compound action potentials were  determined from sciatic nerves of this group.  The other rats were continued to be treated  with Cd (Cd 2 group) or tap water (C and NCd  groups) for an additional 38 days. On PND,  60, the same measurements wer made for  these groups as mentioned above.  The means of the peripheral conduction ve-locities  decreased significanty in all the Cd-treated  groups compared with control group.  The mean of the compound action potential  amplitudes was significantly decreased only in  Cd 2 group compared with control group.

Makale detayları

The Effect of Pre-and Postnatal Cd Exposure on Conduction Velocity in Sciatic Nerve

Yazarlar:

Piraye YARGIÇOĞLU

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 1998 Vol.28 Issue 1, pp.47-52

Belge Tipi:

Makale

Yayın Tarihi:

12/1997

Belge Dili:

Türkçe

Document ID (Org No.):

2000758501

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144

Turk J Med Sci 1998; 28(1): 47-52. Full text: pdf Other articles published in the same issue: Turk J Med Sci

vol.28

iss.1.

Sayı

Makale detayları

The Effect of Pre-and Postnatal Cd Exposure on Conduction Velocity in Sciatic Nerve

Yazarlar: Piraye YARGIÇOĞLU

Yayıncı: TUBITAK

Dergi: Turkish Journal of Medical Sciences 1998 Vol.28 Issue 1, pp.47-52

Belge Tipi: Makale

Yayın Tarihi: 12/1997

Belge Dili: Türkçe

Document ID (Org No.): 2000758501

Sıklık: İki Aylık

eISSN: 1303-6165

pISSN: 1300-0144

Turk J Med Sci 1998; 28(1): 47-52. Full text: pdf Other articles published in the same issue: Turk J Med Sci

vol.28

iss.1.

Sayı

Yazarlar:

Piraye YARGIÇOĞLU

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 1998 Vol.28 Issue 1, pp.47-52

Belge Tipi:

Makale

Yayın Tarihi:

12/1997

Belge Dili:

Türkçe

Document ID (Org No.):

2000758501

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144