Evaluation of conventional karyotyping, lactate dehydrogenase levels, white blood cell count, and bone marrow blast percentage as good prognostic tests in patients with acute lymphoblastic leukemia

N.A.

Makale detayları

Evaluation of conventional karyotyping, lactate dehydrogenase levels, white blood cell count, and bone marrow blast percentage as good prognostic tests in patients with acute lymphoblastic leukemia

Yazarlar:

N.A.

Yayıncı:

Marmara University

Ana Başlıklar:

Pharmacology and Pharmaceutical Sciences (Other)

Dergi:

Journal of Research in Pharmacy Vol.27 Issue 6, pp.2342-2352

Belge Tipi:

Makale

Yayın Tarihi:

6/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001346300

pISSN:

2630-6344

Anahtar kelimeler:

Özet:

 Acute lymphoblastic leukemia is a specific type of hematologic neoplasm in which outcomes may be affected by many variables such as the patients age, gender, conventional karyotyping reports, lactate dehydrogenase concentration, and white blood cell count at diagnosis. The aim of this study was to assess the prognostic significance of those factors on the overall survival of patients diagnosed with ALL. The current study includes 65 patients diagnosed with ALL who were tested for cytology, conventional karyotyping, and immunophenotyping. The results of the current study have indicated the average patients age was 14 years old. In addition, around 47.7 of patients had chromosomal abnormalities. Furthermore, the patients with LDH levels higher than 450 IUL, and WBC counts over 100 X109 Cell L had a shorter overall survival in month compared to other groups. However, the results suggested that conventional karyotyping, LDH, and WBC count might be used as good prognostic tests in patients with ALL at diagnosis.

 Acute lymphoblastic leukemia is a specific type of hematologic neoplasm in which outcomes may be affected by many variables such as the patients age, gender, conventional karyotyping reports, lactate dehydrogenase concentration, and white blood cell count at diagnosis. The aim of this study was to assess the prognostic significance of those factors on the overall survival of patients diagnosed with ALL. The current study includes 65 patients diagnosed with ALL who were tested for cytology, conventional karyotyping, and immunophenotyping. The results of the current study have indicated the average patients age was 14 years old. In addition, around 47.7 of patients had chromosomal abnormalities. Furthermore, the patients with LDH levels higher than 450 IUL, and WBC counts over 100 X109 Cell L had a shorter overall survival in month compared to other groups. However, the results suggested that conventional karyotyping, LDH, and WBC count might be used as good prognostic tests in patients with ALL at diagnosis.

 Acute lymphoblastic leukemia is a specific type of hematologic neoplasm in which outcomes may be affected by many variables such as the patients age, gender, conventional karyotyping reports, lactate dehydrogenase concentration, and white blood cell count at diagnosis. The aim of this study was to assess the prognostic significance of those factors on the overall survival of patients diagnosed with ALL. The current study includes 65 patients diagnosed with ALL who were tested for cytology, conventional karyotyping, and immunophenotyping. The results of the current study have indicated the average patients age was 14 years old. In addition, around 47.7 of patients had chromosomal abnormalities. Furthermore, the patients with LDH levels higher than 450 IUL, and WBC counts over 100 X109 Cell L had a shorter overall survival in month compared to other groups. However, the results suggested that conventional karyotyping, LDH, and WBC count might be used as good prognostic tests in patients with ALL at diagnosis.

 Acute lymphoblastic leukemia is a specific type of hematologic neoplasm in which outcomes may be affected by many variables such as the patients age, gender, conventional karyotyping reports, lactate dehydrogenase concentration, and white blood cell count at diagnosis. The aim of this study was to assess the prognostic significance of those factors on the overall survival of patients diagnosed with ALL. The current study includes 65 patients diagnosed with ALL who were tested for cytology, conventional karyotyping, and immunophenotyping. The results of the current study have indicated the average patients age was 14 years old. In addition, around 47.7 of patients had chromosomal abnormalities. Furthermore, the patients with LDH levels higher than 450 IUL, and WBC counts over 100 X109 Cell L had a shorter overall survival in month compared to other groups. However, the results suggested that conventional karyotyping, LDH, and WBC count might be used as good prognostic tests in patients with ALL at diagnosis.

Makale detayları

Evaluation of conventional karyotyping, lactate dehydrogenase levels, white blood cell count, and bone marrow blast percentage as good prognostic tests in patients with acute lymphoblastic leukemia

Yazarlar:

N.A.

Yayıncı:

Marmara University

Ana Başlıklar:

Pharmacology and Pharmaceutical Sciences (Other)

Dergi:

Journal of Research in Pharmacy Vol.27 Issue 6, pp.2342-2352

Belge Tipi:

Makale

Yayın Tarihi:

6/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001346300

pISSN:

2630-6344

Acute lymphoblastic Leukemia

Conventional Karyotyping

LDH

WBC.

Sayı

Makale detayları

Evaluation of conventional karyotyping, lactate dehydrogenase levels, white blood cell count, and bone marrow blast percentage as good prognostic tests in patients with acute lymphoblastic leukemia

Yazarlar: N.A.

Yayıncı: Marmara University

Ana Başlıklar: Pharmacology and Pharmaceutical Sciences (Other)

Dergi: Journal of Research in Pharmacy Vol.27 Issue 6, pp.2342-2352

Belge Tipi: Makale

Yayın Tarihi: 6/2025

Belge Dili: İngilizce

Document ID (Org No.): 2001346300

pISSN: 2630-6344

Acute lymphoblastic Leukemia

Conventional Karyotyping

LDH

WBC.

Sayı

Yazarlar:

N.A.

Yayıncı:

Marmara University

Ana Başlıklar:

Pharmacology and Pharmaceutical Sciences (Other)

Dergi:

Journal of Research in Pharmacy Vol.27 Issue 6, pp.2342-2352

Belge Tipi:

Makale

Yayın Tarihi:

6/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001346300

pISSN:

2630-6344