Evaluation on Antimicrobial Activity of The Lichen Pleurosticta acetabulum

Başaran Dülger; Gorkem Dulger; Bahar Gedik; Seyhan Oran

Makale detayları

Evaluation on Antimicrobial Activity of The Lichen Pleurosticta acetabulum

Yazarlar:

Başaran Dülger | Gorkem Dulger | Bahar Gedik | Seyhan Oran

Yayıncı:

Duzce University

Ana Başlıklar:

Mühendislik

Dergi:

Düzce Üniversitesi Bilim ve Teknoloji Dergisi Vol.11 Issue 1, pp.199-203

Belge Tipi:

Makale

Yayın Tarihi:

1/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001282896

pISSN:

2148-2446

Anahtar kelimeler:

Özet:

 In this study, the ethanol extract of the lichen Pleurosticta acetabulum Neck. Elix  Lumbsch Parmeliaceae was investigated for their antimicrobial activity against various microorganisms by the disc diffusion method. Mycobacterium smegmatis CCM 2067, Micrococcus luteus CCM 169, Staphylococcus aureus ATCC 6538P, Proteus vulgaris ATCC 8427, Pseudomonas aeruginosa ATCC 27853, Listeria monocytogenes ATCC 15313, Klebsiella pneumoniae UC57, Bacillus cereus ATCC 7064, Escherichia coli ATCC 10536, Rhodotorula rubra DSM 70403, Candida albicans ATCC 10231 and Kluyveromyces fragilis ATCC 8608 were used as test microorgams. We have found that the ethanol extract of the lichen has a potential antimicrobial effect against all tested microorganisms, forming inhibition zones between 12.6-22.4 mm, as compared with the standard antibiotics. Notably, the extract has a strong effect against Escherichia coli and Staphylococcus aureus, especially Candida albicans. In conclusion, P. acetabulum may assist in the discovery of new antimicrobial agents that can serve as selective agents or in the preparation of new combined therapeutic drugs. However, the effect of this lichen species on more pathogenic organisms should be investigated and further and detailed pharmacological and toxicological studies should be conducted.

 In this study, the ethanol extract of the lichen Pleurosticta acetabulum Neck. Elix  Lumbsch Parmeliaceae was investigated for their antimicrobial activity against various microorganisms by the disc diffusion method. Mycobacterium smegmatis CCM 2067, Micrococcus luteus CCM 169, Staphylococcus aureus ATCC 6538P, Proteus vulgaris ATCC 8427, Pseudomonas aeruginosa ATCC 27853, Listeria monocytogenes ATCC 15313, Klebsiella pneumoniae UC57, Bacillus cereus ATCC 7064, Escherichia coli ATCC 10536, Rhodotorula rubra DSM 70403, Candida albicans ATCC 10231 and Kluyveromyces fragilis ATCC 8608 were used as test microorgams. We have found that the ethanol extract of the lichen has a potential antimicrobial effect against all tested microorganisms, forming inhibition zones between 12.6-22.4 mm, as compared with the standard antibiotics. Notably, the extract has a strong effect against Escherichia coli and Staphylococcus aureus, especially Candida albicans. In conclusion, P. acetabulum may assist in the discovery of new antimicrobial agents that can serve as selective agents or in the preparation of new combined therapeutic drugs. However, the effect of this lichen species on more pathogenic organisms should be investigated and further and detailed pharmacological and toxicological studies should be conducted.

 In this study, the ethanol extract of the lichen Pleurosticta acetabulum Neck. Elix  Lumbsch Parmeliaceae was investigated for their antimicrobial activity against various microorganisms by the disc diffusion method. Mycobacterium smegmatis CCM 2067, Micrococcus luteus CCM 169, Staphylococcus aureus ATCC 6538P, Proteus vulgaris ATCC 8427, Pseudomonas aeruginosa ATCC 27853, Listeria monocytogenes ATCC 15313, Klebsiella pneumoniae UC57, Bacillus cereus ATCC 7064, Escherichia coli ATCC 10536, Rhodotorula rubra DSM 70403, Candida albicans ATCC 10231 and Kluyveromyces fragilis ATCC 8608 were used as test microorgams. We have found that the ethanol extract of the lichen has a potential antimicrobial effect against all tested microorganisms, forming inhibition zones between 12.6-22.4 mm, as compared with the standard antibiotics. Notably, the extract has a strong effect against Escherichia coli and Staphylococcus aureus, especially Candida albicans. In conclusion, P. acetabulum may assist in the discovery of new antimicrobial agents that can serve as selective agents or in the preparation of new combined therapeutic drugs. However, the effect of this lichen species on more pathogenic organisms should be investigated and further and detailed pharmacological and toxicological studies should be conducted.

 Bu çalışmada, Pleurosticta acetabulum Neck. Elix  Lumbsch Parmeliaceae liken türünden elde edilen etanol ekstraktının antimikrobiyal aktivitesi, disk difüzyon yöntemi kullanılarak, Mycobacterium smegmatis CCM 2067, Micrococcus luteus CCM 169, Staphylococcus aureus ATCC 6538P, Proteus vulgaris ATCC 8427, Pseudomonas aeruginosa ATCC 27853, Listeria monocytogenes ATCC 15313, Klebsiella pneumoniae UC57, Bacillus cereus ATCC 7064, Escherichia coli ATCC 10536, Rhodotorula rubra DSM 70403, Candida albicans ATCC 10231 ve Kluyveromyces fragilis ATCC 8608 test mikroorganizmalarına karşı araştırılmıştır. Standart antibiyotikleri ile karşılaştırıldığında, elde edilen etanol ekstraktının tüm test mikroorganizmalarına karşı 12.6-22.4 mm değerleri arasında potansiyel bir aktivite gösterdiği belirlenmiştir. Sonuç olarak, P. acetabulum seçici ajan olarak hizmet edebilecek yeni antimikrobiyal ajanların keşfedilmesinde veya yeni konbine terapotik ilaçların hazırlanmasında yardımcı olabilir. Ancak bu liken türünün daha fazla mikroorganizmalar üzerindeki etkisinin araştırılması, daha ileri ve detaylı farmakolojik ve toksikolojik araştırmaların yapılması gerekmektedir.

Makale detayları

Evaluation on Antimicrobial Activity of The Lichen Pleurosticta acetabulum

Yazarlar:

Başaran Dülger | Gorkem Dulger | Bahar Gedik | Seyhan Oran

Yayıncı:

Duzce University

Ana Başlıklar:

Mühendislik

Dergi:

Düzce Üniversitesi Bilim ve Teknoloji Dergisi Vol.11 Issue 1, pp.199-203

Belge Tipi:

Makale

Yayın Tarihi:

1/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001282896

pISSN:

2148-2446

Pleurosticta acetabulum

The lichen

Antimicrobial activity

Pleurosticta acetabulum

Liken

Antimikrobiyal aktivite

The lichen

Antimicrobial activity

Sayı

Makale detayları

Yazarlar: Başaran Dülger | Gorkem Dulger | Bahar Gedik | Seyhan Oran

Yayıncı: Duzce University

Ana Başlıklar: Mühendislik

Dergi: Düzce Üniversitesi Bilim ve Teknoloji Dergisi Vol.11 Issue 1, pp.199-203

Belge Tipi: Makale

Yayın Tarihi: 1/2023

Belge Dili: İngilizce

Document ID (Org No.): 2001282896

pISSN: 2148-2446

Sayı

Yazarlar:

Başaran Dülger | Gorkem Dulger | Bahar Gedik | Seyhan Oran

Yayıncı:

Duzce University

Ana Başlıklar:

Mühendislik

Dergi:

Düzce Üniversitesi Bilim ve Teknoloji Dergisi Vol.11 Issue 1, pp.199-203

Belge Tipi:

Makale

Yayın Tarihi:

1/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001282896

pISSN:

2148-2446