Unlocking traditional remedy: Gulkand-enhanced mucoadhesive gel for canker sore relief

Annegowda Hardur Venkatappa

Makale detayları

Unlocking traditional remedy: Gulkand-enhanced mucoadhesive gel for canker sore relief

Yazarlar:

Annegowda Hardur Venkatappa

Yayıncı:

İzzet KARA

Ana Başlıklar:

Pharmacognosy

Dergi:

International Journal of Secondary Metabolite Vol.11 Issue 4, pp.658-674

Belge Tipi:

Makale

Yayın Tarihi:

3/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001326690

pISSN:

2148-6905

Anahtar kelimeler:

Özet:

 This study focuses on the development and evaluation of mucoadhesive gel formulations containing different Gulkand and its extract with a specific emphasis on their potential for managing oral health conditions, including the discomforting issue of mouth ulcers. The formulations underwent a thorough analysis, encompassing the assessment of phenolic compounds responsible for antioxidant activity, in addition to comprehensive physical, chemical, and pharmacological evaluations to determine their suitability for commercial utilization. Mouth ulcers are a prevalent oral health concern that can cause significant discomfort and inconvenience. In this study, Gulkand extract exhibited remarkable characteristics with its high phenolic content and robust antioxidant activity. It demonstrated rapid drug release, positioning it as a promising new for addressing the immediate relief needs of individuals suffering from mouth ulcers. Conversely, gel formulation showcased a sustained release profile suggesting the potential for longer therapeutic benefits, presents an intriguing option for oral health applications, capitalizing on the antiulcer properties associated with liquorice. An innovative aspect of this study is the compatibility assessment, which employed antioxidant and phenolic content analysis to verify the harmonious interaction between herbal constituents and excipients. This approach introduces novel perspective on compatibility testing, particularly critical for formulations designed to alleviate oral discomfort effectively. Furthermore, stability studies are warranted to be evaluated prior to their potential for commercialization. The present study revealed the promising potential of the prepared mucoadhesive gels in managing not only mouth ulcers but also a spectrum of oral health conditions, holding broader implications for advancements in the field of medicine.

 This study focuses on the development and evaluation of mucoadhesive gel formulations containing different Gulkand and its extract with a specific emphasis on their potential for managing oral health conditions, including the discomforting issue of mouth ulcers. The formulations underwent a thorough analysis, encompassing the assessment of phenolic compounds responsible for antioxidant activity, in addition to comprehensive physical, chemical, and pharmacological evaluations to determine their suitability for commercial utilization. Mouth ulcers are a prevalent oral health concern that can cause significant discomfort and inconvenience. In this study, Gulkand extract exhibited remarkable characteristics with its high phenolic content and robust antioxidant activity. It demonstrated rapid drug release, positioning it as a promising new for addressing the immediate relief needs of individuals suffering from mouth ulcers. Conversely, gel formulation showcased a sustained release profile suggesting the potential for longer therapeutic benefits, presents an intriguing option for oral health applications, capitalizing on the antiulcer properties associated with liquorice. An innovative aspect of this study is the compatibility assessment, which employed antioxidant and phenolic content analysis to verify the harmonious interaction between herbal constituents and excipients. This approach introduces novel perspective on compatibility testing, particularly critical for formulations designed to alleviate oral discomfort effectively. Furthermore, stability studies are warranted to be evaluated prior to their potential for commercialization. The present study revealed the promising potential of the prepared mucoadhesive gels in managing not only mouth ulcers but also a spectrum of oral health conditions, holding broader implications for advancements in the field of medicine.

 This study focuses on the development and evaluation of mucoadhesive gel formulations containing different Gulkand and its extract with a specific emphasis on their potential for managing oral health conditions, including the discomforting issue of mouth ulcers. The formulations underwent a thorough analysis, encompassing the assessment of phenolic compounds responsible for antioxidant activity, in addition to comprehensive physical, chemical, and pharmacological evaluations to determine their suitability for commercial utilization. Mouth ulcers are a prevalent oral health concern that can cause significant discomfort and inconvenience. In this study, Gulkand extract exhibited remarkable characteristics with its high phenolic content and robust antioxidant activity. It demonstrated rapid drug release, positioning it as a promising new for addressing the immediate relief needs of individuals suffering from mouth ulcers. Conversely, gel formulation showcased a sustained release profile suggesting the potential for longer therapeutic benefits, presents an intriguing option for oral health applications, capitalizing on the antiulcer properties associated with liquorice. An innovative aspect of this study is the compatibility assessment, which employed antioxidant and phenolic content analysis to verify the harmonious interaction between herbal constituents and excipients. This approach introduces novel perspective on compatibility testing, particularly critical for formulations designed to alleviate oral discomfort effectively. Furthermore, stability studies are warranted to be evaluated prior to their potential for commercialization. The present study revealed the promising potential of the prepared mucoadhesive gels in managing not only mouth ulcers but also a spectrum of oral health conditions, holding broader implications for advancements in the field of medicine.

 This study focuses on the development and evaluation of mucoadhesive gel formulations containing different Gulkand and its extract with a specific emphasis on their potential for managing oral health conditions, including the discomforting issue of mouth ulcers. The formulations underwent a thorough analysis, encompassing the assessment of phenolic compounds responsible for antioxidant activity, in addition to comprehensive physical, chemical, and pharmacological evaluations to determine their suitability for commercial utilization. Mouth ulcers are a prevalent oral health concern that can cause significant discomfort and inconvenience. In this study, Gulkand extract exhibited remarkable characteristics with its high phenolic content and robust antioxidant activity. It demonstrated rapid drug release, positioning it as a promising new for addressing the immediate relief needs of individuals suffering from mouth ulcers. Conversely, gel formulation showcased a sustained release profile suggesting the potential for longer therapeutic benefits, presents an intriguing option for oral health applications, capitalizing on the antiulcer properties associated with liquorice. An innovative aspect of this study is the compatibility assessment, which employed antioxidant and phenolic content analysis to verify the harmonious interaction between herbal constituents and excipients. This approach introduces novel perspective on compatibility testing, particularly critical for formulations designed to alleviate oral discomfort effectively. Furthermore, stability studies are warranted to be evaluated prior to their potential for commercialization. The present study revealed the promising potential of the prepared mucoadhesive gels in managing not only mouth ulcers but also a spectrum of oral health conditions, holding broader implications for advancements in the field of medicine.

Makale detayları

Unlocking traditional remedy: Gulkand-enhanced mucoadhesive gel for canker sore relief

Yazarlar:

Annegowda Hardur Venkatappa

Yayıncı:

İzzet KARA

Ana Başlıklar:

Pharmacognosy

Dergi:

International Journal of Secondary Metabolite Vol.11 Issue 4, pp.658-674

Belge Tipi:

Makale

Yayın Tarihi:

3/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001326690

pISSN:

2148-6905

Oral discomfort

Traditional remedies

Rose petal jam

Compatibility studies

Buccal mucoadhesive gelOral discomfort

Traditional remedies

Rose petal jam

Compatibility studies

Buccal mucoadhesive gel

Sayı

Makale detayları

Yazarlar: Annegowda Hardur Venkatappa

Yayıncı: İzzet KARA

Ana Başlıklar: Pharmacognosy

Dergi: International Journal of Secondary Metabolite Vol.11 Issue 4, pp.658-674

Belge Tipi: Makale

Yayın Tarihi: 3/2024

Belge Dili: İngilizce

Document ID (Org No.): 2001326690

pISSN: 2148-6905

Sayı

Yazarlar:

Annegowda Hardur Venkatappa

Yayıncı:

İzzet KARA

Ana Başlıklar:

Pharmacognosy

Dergi:

International Journal of Secondary Metabolite Vol.11 Issue 4, pp.658-674

Belge Tipi:

Makale

Yayın Tarihi:

3/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001326690

pISSN:

2148-6905