Determination of Structure-Toxicity Relationship of Amphiprotic Compounds by Means of the Inhibition of the Dehydrogenase Activity of Pseudomonas Putida

Şermin GÜL; Dilek ÖZTÜRK

Makale detayları

Determination of Structure-Toxicity Relationship of Amphiprotic Compounds by Means of the Inhibition of the Dehydrogenase Activity of Pseudomonas Putida

Yazarlar:

Şermin GÜL | Dilek ÖZTÜRK

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Chemistry 1998 Vol.22 Issue 4, pp.341-350

Belge Tipi:

Makale

Yayın Tarihi:

3/1998

Belge Dili:

Türkçe

Document ID (Org No.):

2000730534

Sıklık:

İki Aylık

eISSN:

1303-6130

pISSN:

1300-0527

Özet:

 

Aliphatic and aromatic alcohols are amphiprotic compounds which have both polar and nonpolar parts in their structure. These compounds were studied with respect to the nonreactive toxic effects on the microorganism {\it Pseudomonas putida}. The toxicity of these chemicals to aerobic bacterium {\it P. putida} was measured in terms of inhibition of dehydrogenase activity. The test results, expressed as concentration of chemicals 50% effective in inhibition (IC50), were correlated with their physicochemical properties such as aqueous solubility (S) and octanol-water partition coefficient (P).

 

Aliphatic and aromatic alcohols are amphiprotic compounds which have both polar and nonpolar parts in their structure. These compounds were studied with respect to the nonreactive toxic effects on the microorganism {\it Pseudomonas putida}. The toxicity of these chemicals to aerobic bacterium {\it P. putida} was measured in terms of inhibition of dehydrogenase activity. The test results, expressed as concentration of chemicals 50% effective in inhibition (IC50), were correlated with their physicochemical properties such as aqueous solubility (S) and octanol-water partition coefficient (P).

Makale detayları

Determination of Structure-Toxicity Relationship of Amphiprotic Compounds by Means of the Inhibition of the Dehydrogenase Activity of Pseudomonas Putida

Yazarlar: Şermin GÜL | Dilek ÖZTÜRK

Yayıncı: TUBITAK

Dergi: Turkish Journal of Chemistry 1998 Vol.22 Issue 4, pp.341-350

Belge Tipi: Makale

Yayın Tarihi: 3/1998

Belge Dili: Türkçe

Document ID (Org No.): 2000730534

Sıklık: İki Aylık

eISSN: 1303-6130

pISSN: 1300-0527

Sayı

Yazarlar:

Şermin GÜL | Dilek ÖZTÜRK

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Chemistry 1998 Vol.22 Issue 4, pp.341-350

Belge Tipi:

Makale

Yayın Tarihi:

3/1998

Belge Dili:

Türkçe

Document ID (Org No.):

2000730534

Sıklık:

İki Aylık

eISSN:

1303-6130

pISSN:

1300-0527