One-pot synthesis of fully substituted 1,3,4-oxadiazole derivatives from aromatic carboxylic acids, cyclobutanone and N -isocyaniminotriphenylphosphorane

Mohsen VALIZADEH HOLAGH; Abel Mohammadali oglu MAHARRAMOV

doi:https://doi.org/10.3906/zoo-1202-16

Makale detayları

One-pot synthesis of fully substituted 1,3,4-oxadiazole derivatives from aromatic carboxylic acids, cyclobutanone and N -isocyaniminotriphenylphosphorane

Yazarlar:

Mohsen VALIZADEH HOLAGH | Abel Mohammadali oglu MAHARRAMOV

Yayıncı:

TUBITAK

Ana Başlıklar:

Uygulamalı fizik

Dergi:

Turkish Journal of Chemistry 2012 Vol.36 Issue 1, pp.179-188

Belge Tipi:

Makale

Yayın Tarihi:

12/2011

Belge Dili:

İngilizce

Document ID (Org No.):

2000727710

Sıklık:

İki Aylık

eISSN:

1303-6130

pISSN:

1300-0527

DOI:

https://doi.org/10.3906/zoo-1202-16

Özet:

 

Reactions of N-isocyaniminotriphenylphosphorane with  cyclobutanone in the presence of aromatic (or heteroaromatic)  carboxylic acids proceeded smoothly at room temperature and in neutral  conditions to afford sterically congested 1-(5-aryl-1,3,4-oxadiazol-2-yl)-  1-cyclobutanol derivatives in high yields.  The reaction proceeded  smoothly and cleanly under mild conditions and no side reactions were  observed.  The structures of the products were deduced from their IR,  1HNMR, and 13CNMR spectra, and mass spectrometry.

 

Reactions of N-isocyaniminotriphenylphosphorane with  cyclobutanone in the presence of aromatic (or heteroaromatic)  carboxylic acids proceeded smoothly at room temperature and in neutral  conditions to afford sterically congested 1-(5-aryl-1,3,4-oxadiazol-2-yl)-  1-cyclobutanol derivatives in high yields.  The reaction proceeded  smoothly and cleanly under mild conditions and no side reactions were  observed.  The structures of the products were deduced from their IR,  1HNMR, and 13CNMR spectra, and mass spectrometry.

Makale detayları

One-pot synthesis of fully substituted 1,3,4-oxadiazole derivatives from aromatic carboxylic acids, cyclobutanone and N -isocyaniminotriphenylphosphorane

Yazarlar: Mohsen VALIZADEH HOLAGH | Abel Mohammadali oglu MAHARRAMOV

Yayıncı: TUBITAK

Ana Başlıklar: Uygulamalı fizik

Dergi: Turkish Journal of Chemistry 2012 Vol.36 Issue 1, pp.179-188

Belge Tipi: Makale

Yayın Tarihi: 12/2011

Belge Dili: İngilizce

Document ID (Org No.): 2000727710

Sıklık: İki Aylık

eISSN: 1303-6130

pISSN: 1300-0527

DOI: https://doi.org/10.3906/zoo-1202-16

Sayı

Yazarlar:

Mohsen VALIZADEH HOLAGH | Abel Mohammadali oglu MAHARRAMOV

Yayıncı:

TUBITAK

Ana Başlıklar:

Uygulamalı fizik

Dergi:

Turkish Journal of Chemistry 2012 Vol.36 Issue 1, pp.179-188

Belge Tipi:

Makale

Yayın Tarihi:

12/2011

Belge Dili:

İngilizce

Document ID (Org No.):

2000727710

Sıklık:

İki Aylık

eISSN:

1303-6130

pISSN:

1300-0527

DOI:

https://doi.org/10.3906/zoo-1202-16