Incidence and risk factors of contrast-induced nephropathy after diagnostic or interventional coronary angiography

Hasan ARİ; Selvi OZTAS COSAR; Selma ARİ; Kubra Doganay; Cihan AYDİN; Nadir EMLEK; Nuran CELİLOGLU; Ahmet Seckin CETİNKAYA; Tahsin BOZAT; Mehmet MELEK

doi:https://doi.org/10.18621/eurj.2016.5000200322

Makale detayları

Incidence and risk factors of contrast-induced nephropathy after diagnostic or interventional coronary angiography

Yazarlar:

Hasan ARİ | Selvi OZTAS COSAR | Selma ARİ | Kubra Doganay | Cihan AYDİN | Nadir EMLEK | Nuran CELİLOGLU | Ahmet Seckin CETİNKAYA | Tahsin BOZAT | Mehmet MELEK

Yayıncı:

Prusa Medical Publishing

Ana Başlıklar:

Sağlık teşvikleri

Dergi:

The European Research Journal 2017 Vol.3 Issue 1, pp.16-24

Belge Tipi:

Makale

Yayın Tarihi:

3/2017

Belge Dili:

Türkçe

Document ID (Org No.):

2000663439

Sıklık:

İki Aylık

eISSN:

2149-3189

DOI:

https://doi.org/10.18621/eurj.2016.5000200322

Özet:

 


Objectives. Contrast-induced nephropathy (CIN) is the third most common cause of acute renal failure that occurred in the hospital. In Turkey, there is not enough data about the frequency of CIN in cardiological interventions. Increased contrast volume and creatinin value are related with CIN. We also investigated the CIN predictors. Methods. A total of 2604 patients who underwent coronary angiography or percutaneous coronary intervention (PCI) in our hospital were prospectively evaluated in terms of CIN. The definition of CIN includes absolute (≥0.5mg/dl) or relative increase (≥25%) in serum creatinine at 48-72 h after exposure to a contrast agent compared to baseline serum creatinine values. Results. CIN was detected in 13.6% (355 patients) of 2604 patients. According to the procedure; CIN rate was 13.3% (280 of 2108 patients) in coronary angiography, 13.08% (50 of 382 patients) in elective PCI and 21.49% (25 of 114 patients) in primary PCI. Compared with each of these three groups patients, CIN rate was significantly higher in primary PCI group than coronary angiography (p=0.009) and elective PCI (p=0.02) groups. In multivariate analysis, age (odds ratio [OR]=1.04; 95% confidence interval [CI], 1.02-1.06; p<0.001), glomerular filtration rate (OR=0.99; 95% CI, 0.98-0.99; p<0.001), contrast volume (OR=1.14; 95% CI, 1.007-1.21; p<0.006), contrast volume to creatinine ratio (OR=1.01; 95% CI, 1.009-1.02; p<0.001), three vessel disease (OR=1.77, 95% CI, 1.24-2.51; p=0.001) were independent predictors of CIN. Conclusions. In our patient population, the incidence of CIN was found to be 13.6% in cardiological interventions. In emergency interventions, incidence of CIN was increased. We found that contrast volume to creatinine ratio is predictor of CIN. 

.

Makale detayları

Incidence and risk factors of contrast-induced nephropathy after diagnostic or interventional coronary angiography

Yazarlar: Hasan ARİ | Selvi OZTAS COSAR | Selma ARİ | Kubra Doganay | Cihan AYDİN | Nadir EMLEK | Nuran CELİLOGLU | Ahmet Seckin CETİNKAYA | Tahsin BOZAT | Mehmet MELEK

Yayıncı: Prusa Medical Publishing

Ana Başlıklar: Sağlık teşvikleri

Dergi: The European Research Journal 2017 Vol.3 Issue 1, pp.16-24

Belge Tipi: Makale

Yayın Tarihi: 3/2017

Belge Dili: Türkçe

Document ID (Org No.): 2000663439

Sıklık: İki Aylık

eISSN: 2149-3189

DOI: https://doi.org/10.18621/eurj.2016.5000200322

Sayı

Yazarlar:

Hasan ARİ | Selvi OZTAS COSAR | Selma ARİ | Kubra Doganay | Cihan AYDİN | Nadir EMLEK | Nuran CELİLOGLU | Ahmet Seckin CETİNKAYA | Tahsin BOZAT | Mehmet MELEK

Yayıncı:

Prusa Medical Publishing

Ana Başlıklar:

Sağlık teşvikleri

Dergi:

The European Research Journal 2017 Vol.3 Issue 1, pp.16-24

Belge Tipi:

Makale

Yayın Tarihi:

3/2017

Belge Dili:

Türkçe

Document ID (Org No.):

2000663439

Sıklık:

İki Aylık

eISSN:

2149-3189

DOI:

https://doi.org/10.18621/eurj.2016.5000200322