Biomedical Potential of p(Rt) Particles Synthesized from Rubia Tinctorum L. Extract: Characterization, Bioactivity and Controlled Drug Release

Duygu Alpaslan; Abdullah Turan

Makale detayları

Biomedical Potential of p(Rt) Particles Synthesized from Rubia Tinctorum L. Extract: Characterization, Bioactivity and Controlled Drug Release

Yazarlar:

Duygu Alpaslan | Abdullah Turan

Yayıncı:

Turkish Chemical Society

Ana Başlıklar:

Biomaterial

Dergi:

Journal of the Turkish Chemical Society Section B: Chemical Engineering Vol.8 Issue 2, pp.185-202

Belge Tipi:

Makale

Yayın Tarihi:

9/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001344878

pISSN:

2564-6907

Anahtar kelimeler:

Özet:

 Rubia tinctorum L. Root Dye, Madder has been historically used in textile dyeing and is valued for its natural antibacterial, antioxidant, and therapeutic properties. In this study, the synthesis of polyRubia tinctorum pRt particles from Rubia tinctorum L. extract and their biomedical applications are reported for the first time. The extract and synthesized particles were characterized using SEM, FTIR, DLS, zeta potential analysis, and HPLC. The bioactivity of pRt particles, including antimicrobial, antioxidant, and biocompatibility properties, were assessed. Drug release studies showed significant paracetamol and ceftriaxone release at different pH levels, with release kinetics fitting the Korsmeyer-Peppas model. This study highlights the novelty of pRt particles and their potential in biomedical applications, particularly in drug delivery.

 Rubia tinctorum L. Root Dye, Madder has been historically used in textile dyeing and is valued for its natural antibacterial, antioxidant, and therapeutic properties. In this study, the synthesis of polyRubia tinctorum pRt particles from Rubia tinctorum L. extract and their biomedical applications are reported for the first time. The extract and synthesized particles were characterized using SEM, FTIR, DLS, zeta potential analysis, and HPLC. The bioactivity of pRt particles, including antimicrobial, antioxidant, and biocompatibility properties, were assessed. Drug release studies showed significant paracetamol and ceftriaxone release at different pH levels, with release kinetics fitting the Korsmeyer-Peppas model. This study highlights the novelty of pRt particles and their potential in biomedical applications, particularly in drug delivery.

 Rubia tinctorum L. Root Dye, Madder has been historically used in textile dyeing and is valued for its natural antibacterial, antioxidant, and therapeutic properties. In this study, the synthesis of polyRubia tinctorum pRt particles from Rubia tinctorum L. extract and their biomedical applications are reported for the first time. The extract and synthesized particles were characterized using SEM, FTIR, DLS, zeta potential analysis, and HPLC. The bioactivity of pRt particles, including antimicrobial, antioxidant, and biocompatibility properties, were assessed. Drug release studies showed significant paracetamol and ceftriaxone release at different pH levels, with release kinetics fitting the Korsmeyer-Peppas model. This study highlights the novelty of pRt particles and their potential in biomedical applications, particularly in drug delivery.

 Rubia tinctorum L. Root Dye, Madder has been historically used in textile dyeing and is valued for its natural antibacterial, antioxidant, and therapeutic properties. In this study, the synthesis of polyRubia tinctorum pRt particles from Rubia tinctorum L. extract and their biomedical applications are reported for the first time. The extract and synthesized particles were characterized using SEM, FTIR, DLS, zeta potential analysis, and HPLC. The bioactivity of pRt particles, including antimicrobial, antioxidant, and biocompatibility properties, were assessed. Drug release studies showed significant paracetamol and ceftriaxone release at different pH levels, with release kinetics fitting the Korsmeyer-Peppas model. This study highlights the novelty of pRt particles and their potential in biomedical applications, particularly in drug delivery.

Makale detayları

Biomedical Potential of p(Rt) Particles Synthesized from Rubia Tinctorum L. Extract: Characterization, Bioactivity and Controlled Drug Release

Yazarlar:

Duygu Alpaslan | Abdullah Turan

Yayıncı:

Turkish Chemical Society

Ana Başlıklar:

Biomaterial

Dergi:

Journal of the Turkish Chemical Society Section B: Chemical Engineering Vol.8 Issue 2, pp.185-202

Belge Tipi:

Makale

Yayın Tarihi:

9/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001344878

pISSN:

2564-6907

Antimicrobial

Antioxidant

Biocompatibility

Drug release

Sayı

Makale detayları

Biomedical Potential of p(Rt) Particles Synthesized from Rubia Tinctorum L. Extract: Characterization, Bioactivity and Controlled Drug Release

Yazarlar: Duygu Alpaslan | Abdullah Turan

Yayıncı: Turkish Chemical Society

Ana Başlıklar: Biomaterial

Dergi: Journal of the Turkish Chemical Society Section B: Chemical Engineering Vol.8 Issue 2, pp.185-202

Belge Tipi: Makale

Yayın Tarihi: 9/2025

Belge Dili: İngilizce

Document ID (Org No.): 2001344878

pISSN: 2564-6907

Antimicrobial

Antioxidant

Biocompatibility

Drug release

Sayı

Yazarlar:

Duygu Alpaslan | Abdullah Turan

Yayıncı:

Turkish Chemical Society

Ana Başlıklar:

Biomaterial

Dergi:

Journal of the Turkish Chemical Society Section B: Chemical Engineering Vol.8 Issue 2, pp.185-202

Belge Tipi:

Makale

Yayın Tarihi:

9/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001344878

pISSN:

2564-6907