Kaposi Sarcoma: Single Center 10 Years Of Experience

Şeyhmus Kaya; Sedanur Aydın; Ramazan Oğuz Yüceer; Tülay Koç; Reyhan Eğilmez

Makale detayları

Kaposi Sarcoma: Single Center 10 Years Of Experience

Yazarlar:

Şeyhmus Kaya | Sedanur Aydın | Ramazan Oğuz Yüceer | Tülay Koç | Reyhan Eğilmez

Yayıncı:

Manisa Celal Bayar University

Ana Başlıklar:

Patoloji

Dergi:

Celal Bayar Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi Vol.12 Issue 1, pp.88-91

Belge Tipi:

Makale

Yayın Tarihi:

3/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001343458

pISSN:

2147-9607

Anahtar kelimeler:

Özet:

 Aim: Kaposi sarcoma is a rare angioproliferative disease associated with human herpesvirus-8. There are limited studies in our country regarding its epidemiology and clinical features. This study aims to explore cases diagnosed with Kaposi sarcoma at Sivas Cumhuriyet University Medical Faculty Research Hospital. Materials and Methods: The records of patients n:18 diagnosed with Kaposi sarcoma between January 1, 2013, and June 30, 2023, in the Department of Medical Pathology were retrospectively reviewed. When recurrences were considered, the total number of cases increased to 27. The clinical, histopathological, and demographic characteristics of the patients were examined. Results:The mean age of the patients was 69.313.3 years range:3288. Thirteen patients 72.2 were male, and five 27.7 were female. None of the patients had a history of HIV. Of the lesions, 66.6 n12 were localized in the lower extremities, 22.2 n4 in the upper extremities, and 11.1 n2 in non-extremity regions. Histopathological examination revealed that 72.7 n13 of the patients were in the tumor nodule stage, 22.2 n4 in the patch stage, and 5.6 n1 in the plaque stage. All patients were treated surgically. Among the recurrence cases, a total of nine cases involved five patients. Additional diseases observed in the patients included heart disease, hypertension, and diabetes. Conclusion:To better evaluate the demographic data and clinical features of Kaposi sarcoma in our country, multicenter studies are needed, as well as increased awareness of this disease among relevant physicians.

 Aim: Kaposi sarcoma is a rare angioproliferative disease associated with human herpesvirus-8. There are limited studies in our country regarding its epidemiology and clinical features. This study aims to explore cases diagnosed with Kaposi sarcoma at Sivas Cumhuriyet University Medical Faculty Research Hospital. Materials and Methods: The records of patients n:18 diagnosed with Kaposi sarcoma between January 1, 2013, and June 30, 2023, in the Department of Medical Pathology were retrospectively reviewed. When recurrences were considered, the total number of cases increased to 27. The clinical, histopathological, and demographic characteristics of the patients were examined. Results:The mean age of the patients was 69.313.3 years range:3288. Thirteen patients 72.2 were male, and five 27.7 were female. None of the patients had a history of HIV. Of the lesions, 66.6 n12 were localized in the lower extremities, 22.2 n4 in the upper extremities, and 11.1 n2 in non-extremity regions. Histopathological examination revealed that 72.7 n13 of the patients were in the tumor nodule stage, 22.2 n4 in the patch stage, and 5.6 n1 in the plaque stage. All patients were treated surgically. Among the recurrence cases, a total of nine cases involved five patients. Additional diseases observed in the patients included heart disease, hypertension, and diabetes. Conclusion:To better evaluate the demographic data and clinical features of Kaposi sarcoma in our country, multicenter studies are needed, as well as increased awareness of this disease among relevant physicians.

 Aim: Kaposi sarcoma is a rare angioproliferative disease associated with human herpesvirus-8. There are limited studies in our country regarding its epidemiology and clinical features. This study aims to explore cases diagnosed with Kaposi sarcoma at Sivas Cumhuriyet University Medical Faculty Research Hospital. Materials and Methods: The records of patients n:18 diagnosed with Kaposi sarcoma between January 1, 2013, and June 30, 2023, in the Department of Medical Pathology were retrospectively reviewed. When recurrences were considered, the total number of cases increased to 27. The clinical, histopathological, and demographic characteristics of the patients were examined. Results:The mean age of the patients was 69.313.3 years range:3288. Thirteen patients 72.2 were male, and five 27.7 were female. None of the patients had a history of HIV. Of the lesions, 66.6 n12 were localized in the lower extremities, 22.2 n4 in the upper extremities, and 11.1 n2 in non-extremity regions. Histopathological examination revealed that 72.7 n13 of the patients were in the tumor nodule stage, 22.2 n4 in the patch stage, and 5.6 n1 in the plaque stage. All patients were treated surgically. Among the recurrence cases, a total of nine cases involved five patients. Additional diseases observed in the patients included heart disease, hypertension, and diabetes. Conclusion:To better evaluate the demographic data and clinical features of Kaposi sarcoma in our country, multicenter studies are needed, as well as increased awareness of this disease among relevant physicians.

 Amaç: Kaposi sarkomu, human herpes virüs-8 ile ilişkili, ender görülen anjiyoproliferatif hastalıktır. Epidemiyolojisi ve klinik özellikleri ile ilgili olarak ülkemizde sınırlı sayıda çalışma mevcuttur. Bu çalışma Sivas Cumhuriyet Üniversitesi Tıp Fakültesi Araştırma Hastanesinde Kaposi sarkomu tanısı almış olguların epidemiyolojik, klinik ve histomorfolojik özelliklerinin ortaya konması amaçlanmıştır. Gereç ve Yöntem: Tıbbi Patoloji Bölümünde, 1 Ocak 2013- 30 Haziran 2023 tarihleri arasında Kaposi Sarkomu tanısı almış hastalarınn:18 kayıtları geriye dönük olarak incelendi. Nüksler ile birlikte değerlendirildiğinde toplam olgu sayısı 27dir. Hastaların klinik, histopatolojik ve demografik özelikleri incelendi. Bulgular: Hastaların yaş ortalaması 69,3 13,3 minimum 32-maksimum 88tür. Hastaların 13ü 72,2 erkek, 5i  27,7 kadındır. Hastaların hiç birinin HIV öyküsü yoktur. Hastalara ait lezyonların  66,6sı n12 alt ekstremite,  22,si n4 üst ekstremitede, iki hastada ise11,1 ekstremite dışı bölgelerde lokalizedir. Histopatolojik incelemede hastaların  72,7si n13 tümörnodül,  22,2si n4 yama,  5,6sın1 ise plak evresindedir. Hastaların tamamı cerrahi yöntem ile tedavi görmüştür. Nüks eden olgular değerlendirildiğinde toplam 9 olgu, 5 hastaya aittir. Hastalarda görülen ek hastalıklar kalp hastalığı, hipertansiyon ve diyabettir. Sonuç: Ülkemizdeki Kaposi Sarkomunun demografik veri ve klinik özeliklerinin ayrıntılı bir şekilde değerlendirilmesi için çok merkezli çalışmalara ve ilgili hekimler arasında bu hastalık ile ilgili farkındalığın oluşturulması gerekmektedir.

Makale detayları

Kaposi Sarcoma: Single Center 10 Years Of Experience

Yazarlar:

Şeyhmus Kaya | Sedanur Aydın | Ramazan Oğuz Yüceer | Tülay Koç | Reyhan Eğilmez

Yayıncı:

Manisa Celal Bayar University

Ana Başlıklar:

Patoloji

Dergi:

Celal Bayar Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi Vol.12 Issue 1, pp.88-91

Belge Tipi:

Makale

Yayın Tarihi:

3/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001343458

pISSN:

2147-9607

Kaposi sarcoma

HHV8

histopathologyKaposi sarkom

HHV8

histopatoloji

Sayı

Makale detayları

Kaposi Sarcoma: Single Center 10 Years Of Experience

Yazarlar: Şeyhmus Kaya | Sedanur Aydın | Ramazan Oğuz Yüceer | Tülay Koç | Reyhan Eğilmez

Yayıncı: Manisa Celal Bayar University

Ana Başlıklar: Patoloji

Dergi: Celal Bayar Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi Vol.12 Issue 1, pp.88-91

Belge Tipi: Makale

Yayın Tarihi: 3/2025

Belge Dili: İngilizce

Document ID (Org No.): 2001343458

pISSN: 2147-9607

Kaposi sarcoma

HHV8

histopathologyKaposi sarkom

HHV8

histopatoloji

Sayı

Yazarlar:

Şeyhmus Kaya | Sedanur Aydın | Ramazan Oğuz Yüceer | Tülay Koç | Reyhan Eğilmez

Yayıncı:

Manisa Celal Bayar University

Ana Başlıklar:

Patoloji

Dergi:

Celal Bayar Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi Vol.12 Issue 1, pp.88-91

Belge Tipi:

Makale

Yayın Tarihi:

3/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001343458

pISSN:

2147-9607