The importance of clinical and pathological features in  bladder cancer and its effects on disease course

Sahin LACİN; Nilgun SOGUTCU

Makale detayları

The importance of clinical and pathological features in bladder cancer and its effects on disease course

Yazarlar:

Sahin LACİN | Nilgun SOGUTCU

Yayıncı:

Dicle University

Ana Başlıklar:

Sağlık teşvikleri

Dergi:

Dicle Medical Journal 2019 Vol.46 Issue 4, pp.821-829

Belge Tipi:

Makale

Yayın Tarihi:

12/2019

Belge Dili:

İngilizce

Document ID (Org No.):

2000946629

Sıklık:

Üç Aylık

eISSN:

1308-9889

pISSN:

1300-2945

Anahtar kelimeler:

Özet:

 

Objective: Bladder cancer (BC) is the most common malignancy of the urinary system and the incidence of BC varies
regionally. Bladder cancer is more common in men than in women. Tumor stage and grade are the most important
prognostic factors of BC. We aimed to describe the patterns of BC presentation and to examine the differences in the
distribution of prognostic factors by gender, age, tumor size, and involvement region. 
Method: The patients diagnosed with BC (non-muscle invasive or muscle-invasive BC) were included. Intravesical
treatment, tumor diameter, pathological grade, tumor involved area and tumor stage were recorded as variables. The
survival rates of the patients were calculated for diverse clinical and pathological findings. 
Results:In a total of 124 patients, 23 (18.5%) of patients were female and 101(81.5%) of patients were male, the
median age of all patients was 64 (IQR: 21-92). There were 36 % (41) patients in early-stage (stage 0 or stage insitu),
50.9 % (58) patients in stage 1, 7% (8) patients in stage 2, 4.4 %(5) patients in stage 3 and 1.8% (2) patients were in
stage 4. There were significantly different OS rates of patients with BC in different stages (p2.5cm (group 2). There was a
significant difference between the overall survival rates of group 1 and group 2(p=0.02). There were 55 patients with
low-grade BC and 38 of patients with high-grade BC, and the difference between their survival rates was statistically
significant (p=0.001). 
Conclusions: Tumor stage, tumor diameter, and grade were demonstrated and confirmed as the crucial prognostic
factors of bladder cancer. Additionally, lateral walls of bladder constitute the most commonly involved area, but their
roles in the disease course still remain unclear.

Makale detayları

The importance of clinical and pathological features in bladder cancer and its effects on disease course

Yazarlar:

Sahin LACİN | Nilgun SOGUTCU

Yayıncı:

Dicle University

Ana Başlıklar:

Sağlık teşvikleri

Dergi:

Dicle Medical Journal 2019 Vol.46 Issue 4, pp.821-829

Belge Tipi:

Makale

Yayın Tarihi:

12/2019

Belge Dili:

İngilizce

Document ID (Org No.):

2000946629

Sıklık:

Üç Aylık

eISSN:

1308-9889

pISSN:

1300-2945

Bladder cancer

Tumor size

Sayı

Makale detayları

The importance of clinical and pathological features in bladder cancer and its effects on disease course

Yazarlar: Sahin LACİN | Nilgun SOGUTCU

Yayıncı: Dicle University

Ana Başlıklar: Sağlık teşvikleri

Dergi: Dicle Medical Journal 2019 Vol.46 Issue 4, pp.821-829

Belge Tipi: Makale

Yayın Tarihi: 12/2019

Belge Dili: İngilizce

Document ID (Org No.): 2000946629

Sıklık: Üç Aylık

eISSN: 1308-9889

pISSN: 1300-2945

Bladder cancer

Tumor size

Sayı

Yazarlar:

Sahin LACİN | Nilgun SOGUTCU

Yayıncı:

Dicle University

Ana Başlıklar:

Sağlık teşvikleri

Dergi:

Dicle Medical Journal 2019 Vol.46 Issue 4, pp.821-829

Belge Tipi:

Makale

Yayın Tarihi:

12/2019

Belge Dili:

İngilizce

Document ID (Org No.):

2000946629

Sıklık:

Üç Aylık

eISSN:

1308-9889

pISSN:

1300-2945