Primer Hiperparatiroidide Tc-99m MİBİ ile Yapılan Sintigrafik Görüntüleme Sonuçlarının İncelenmesi ve Biyokimyasal Parametreler ile İlişkisinin Değerlendirilmesi

Seda TURGUT; Ezgi Başak ERDOĞAN

Makale detayları

Primer Hiperparatiroidide Tc-99m MİBİ ile Yapılan Sintigrafik Görüntüleme Sonuçlarının İncelenmesi ve Biyokimyasal Parametreler ile İlişkisinin Değerlendirilmesi

Yazarlar:

Seda TURGUT | Ezgi Başak ERDOĞAN

Yayıncı:

Eskişehir Osmangazi University

Ana Başlıklar:

Sağlık teşvikleri

Dergi:

Osmangazi Journal of Medicine 2021 Vol.43 Issue 2, pp.138-148

Belge Tipi:

Makale

Yayın Tarihi:

3/2021

Belge Dili:

Türkçe

Document ID (Org No.):

2000555030

Sıklık:

İki Aylık

eISSN:

2587-1579

pISSN:

1305-4953

Özet:

 


It was aimed to evaluate the relationship between clinical, laboratory, and histopathological findings with the scintigraphy performed with Technetium-99m MIBI in patients with primary hyperparathyroidism (PHPT). 516 patients who applied for parathyroid scintigraphy between 2012-2018 were retrospectively scanned. Files of 105(94 female, 11 male) patients, which were diagnosed as PHPT, were included in the study and laboratory, ultrasonography (USG), and findings were recorded. The scintigraphically parathyroid tissues that can be localized were examined in two groups as MIBI-positive(n=92) and those that could not be MIBI-negative (n=13). Sensitivity and diagnostic accuracy of USG and scintigraphy and combinations were evaluated. The calcium value (11.48±0.75 mg/dl) in MIBI-positive group was higher than MIBI-negative group (11±0.68 mg/dl) (p=0.047). While the sensitivity of USG in lesion detection was 60.2%, and scintigraphy was 89.1%, the sensitivity in the combination of the those was 91.9%. Diagnostic acuity of scintigraphy was 87.6%, USG+scintigraphy was 92%. A positive correlation was found between parathyroid adenoma size and PTH and ALP (p<0.001 r=0.572; p=0.003 r=0.424, respectively). Parathyroid scintigraphy is more likely to define a parathyroid pathology when calcium is high, and the adenoma size increases consistent with increasing PTH. Although scintigraphy is much more effective than USG for preoperative localization in PHPT, its combination with USG contributes to the localization of PHPT.

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Makale detayları

Primer Hiperparatiroidide Tc-99m MİBİ ile Yapılan Sintigrafik Görüntüleme Sonuçlarının İncelenmesi ve Biyokimyasal Parametreler ile İlişkisinin Değerlendirilmesi

Yazarlar: Seda TURGUT | Ezgi Başak ERDOĞAN

Yayıncı: Eskişehir Osmangazi University

Ana Başlıklar: Sağlık teşvikleri

Dergi: Osmangazi Journal of Medicine 2021 Vol.43 Issue 2, pp.138-148

Belge Tipi: Makale

Yayın Tarihi: 3/2021

Belge Dili: Türkçe

Document ID (Org No.): 2000555030

Sıklık: İki Aylık

eISSN: 2587-1579

pISSN: 1305-4953

Sayı

Yazarlar:

Seda TURGUT | Ezgi Başak ERDOĞAN

Yayıncı:

Eskişehir Osmangazi University

Ana Başlıklar:

Sağlık teşvikleri

Dergi:

Osmangazi Journal of Medicine 2021 Vol.43 Issue 2, pp.138-148

Belge Tipi:

Makale

Yayın Tarihi:

3/2021

Belge Dili:

Türkçe

Document ID (Org No.):

2000555030

Sıklık:

İki Aylık

eISSN:

2587-1579

pISSN:

1305-4953