Ultrasonographic Evaluation of Liver Damage and Obstruction of the Biliary Tract in Experimentally  Bile Duct Ligated Dogs

Remzi GÖNÜL; Yücel MERAL; Abdullah KAYAR; Utku BAKIREL; Mehmet Erman OR

Makale detayları

Ultrasonographic Evaluation of Liver Damage and Obstruction of the Biliary Tract in Experimentally Bile Duct Ligated Dogs

Yazarlar:

Remzi GÖNÜL | Yücel MERAL | Abdullah KAYAR | Utku BAKIREL | Mehmet Erman OR

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Veterinary and Animal Sciences 2002 Vol.26 Issue 6, pp.1459-1464

Belge Tipi:

Makale

Yayın Tarihi:

5/2002

Belge Dili:

Türkçe

Document ID (Org No.):

2000770471

Sıklık:

İki Aylık

eISSN:

1303-6181

pISSN:

1300-0128

Anahtar kelimeler:

Özet:

 

The liver damage and obstructions of the biliary tract were evaluated ultrasonographically in experimentally bile duct ligated dogs.  Seven healthy dogs of different breeds were used. The common bile duct was double ligated at the duodenal region after clinical and ultrasonographic examinations. After that, clinical examinations, biochemical analyses and examinations of the liver, gallbladder and biliary tract were done ultrasonographically over 6 weeks. All dogs were necropsied and macroscopic and histologic alterations were determined at the end of the study.  It was determined that the levels of serum ALT, ALP, GGT and T. Bilirubin were (p < 0.001-0.05) statistically significantly increased after the operation in all dogs. As a result of ultrasonographic examinations, it was determined that the bile ducts and gallbladder  were distended, the neck of the gallbladder was larger and more tortuous than normal, hypoechoic sludge was prominent in the gallbladder,  and perivascular, multifocal hyperechoic areas appeared in the liver parenchyma toward the end of the study. These alterations were confirmed macroscopically and microscopically at the end of the autopsy in all dogs.  We consider that as well as blood serum parameters, ultrasonographic examinations are useful in the early diagnosis of biliary diseases and in differentiating them from hepatic diseases.

 

The liver damage and obstructions of the biliary tract were evaluated ultrasonographically in experimentally bile duct ligated dogs.  Seven healthy dogs of different breeds were used. The common bile duct was double ligated at the duodenal region after clinical and ultrasonographic examinations. After that, clinical examinations, biochemical analyses and examinations of the liver, gallbladder and biliary tract were done ultrasonographically over 6 weeks. All dogs were necropsied and macroscopic and histologic alterations were determined at the end of the study.  It was determined that the levels of serum ALT, ALP, GGT and T. Bilirubin were (p < 0.001-0.05) statistically significantly increased after the operation in all dogs. As a result of ultrasonographic examinations, it was determined that the bile ducts and gallbladder  were distended, the neck of the gallbladder was larger and more tortuous than normal, hypoechoic sludge was prominent in the gallbladder,  and perivascular, multifocal hyperechoic areas appeared in the liver parenchyma toward the end of the study. These alterations were confirmed macroscopically and microscopically at the end of the autopsy in all dogs.  We consider that as well as blood serum parameters, ultrasonographic examinations are useful in the early diagnosis of biliary diseases and in differentiating them from hepatic diseases.

Makale detayları

Ultrasonographic Evaluation of Liver Damage and Obstruction of the Biliary Tract in Experimentally Bile Duct Ligated Dogs

Yazarlar:

Remzi GÖNÜL | Yücel MERAL | Abdullah KAYAR | Utku BAKIREL | Mehmet Erman OR

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Veterinary and Animal Sciences 2002 Vol.26 Issue 6, pp.1459-1464

Belge Tipi:

Makale

Yayın Tarihi:

5/2002

Belge Dili:

Türkçe

Document ID (Org No.):

2000770471

Sıklık:

İki Aylık

eISSN:

1303-6181

pISSN:

1300-0128

Dog

ligation

liver

gallbladder

common bile duct

ultrasonography

Sayı

Makale detayları

Ultrasonographic Evaluation of Liver Damage and Obstruction of the Biliary Tract in Experimentally Bile Duct Ligated Dogs

Yazarlar: Remzi GÖNÜL | Yücel MERAL | Abdullah KAYAR | Utku BAKIREL | Mehmet Erman OR

Yayıncı: TUBITAK

Dergi: Turkish Journal of Veterinary and Animal Sciences 2002 Vol.26 Issue 6, pp.1459-1464

Belge Tipi: Makale

Yayın Tarihi: 5/2002

Belge Dili: Türkçe

Document ID (Org No.): 2000770471

Sıklık: İki Aylık

eISSN: 1303-6181

pISSN: 1300-0128

Dog

ligation

liver

gallbladder

common bile duct

ultrasonography

Sayı

Yazarlar:

Remzi GÖNÜL | Yücel MERAL | Abdullah KAYAR | Utku BAKIREL | Mehmet Erman OR

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Veterinary and Animal Sciences 2002 Vol.26 Issue 6, pp.1459-1464

Belge Tipi:

Makale

Yayın Tarihi:

5/2002

Belge Dili:

Türkçe

Document ID (Org No.):

2000770471

Sıklık:

İki Aylık

eISSN:

1303-6181

pISSN:

1300-0128