Antibacterial Activity of Laetiporus sulphureus Extracts Against Multidrug Resistant Bacterial Isolates

Ayşegül Akkoyunlu; Gorkem Dulger; Başaran Dülger

Makale detayları

Antibacterial Activity of Laetiporus sulphureus Extracts Against Multidrug Resistant Bacterial Isolates

Yazarlar:

Ayşegül Akkoyunlu | Gorkem Dulger | Başaran Dülger

Yayıncı:

Selcuk University

Ana Başlıklar:

Mikoloji

Dergi:

Mantar Dergisi Vol.16 Issue 1, pp.1-7

Belge Tipi:

Makale

Yayın Tarihi:

4/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001345928

pISSN:

2147-6845

Anahtar kelimeler:

Özet:

 Ethanol extracts from Laetiporus sulphureus Bull. Murrill Polyporaceae were tested for their antibacterial activity against multidrug-resistant bacterial isolates using agar well diffusion and dilution procedures. According to the findings, L. sulphureuss antibacterial activity differed depending on the extract concentration. While no activity was observed at other dosages, the ethanolic extract demonstrated inhibitory zones ranging from 10.2 to 17.4 mm at 200 mgmL; 8.2 to 12.6 mm at 100 mgmL; and 9.2 to 9.8 mm at 50 mgmL. Klebsiella pneumoniae 10.2 mm at 200 mgmL was the least susceptible to the extract, while Bacillus subtilis 17.4 mm at 200 mgmL was the most sensitive. The extracts minimum inhibitory concentration MIC against Staphylococcus aureus, B. subtilis, and K. pneumoniae ranged between 25 mgmL and 200 mgmL. For B. subtilis, S. aureus, and Pseudomonas aeruginosa, the minimum bactericidal concentration MBC of the extract was recorded at 50 mgmL and 200 mgmL, respectively; however, no MBC was found for K. pneumoniae. S. aureus exhibited the highest level of resistance 70, while P. aeruginosa demonstrated the lowest level of resistance 10. Pefloxacin, ciprofloxacin, septrin, and sparfloxacin were identified as the most potent antibiotics. The findings suggest that L. sulphureus has potential as an antibacterial agent, though its effectiveness varies according to extract concentration and bacterial species.

 Ethanol extracts from Laetiporus sulphureus Bull. Murrill Polyporaceae were tested for their antibacterial activity against multidrug-resistant bacterial isolates using agar well diffusion and dilution procedures. According to the findings, L. sulphureuss antibacterial activity differed depending on the extract concentration. While no activity was observed at other dosages, the ethanolic extract demonstrated inhibitory zones ranging from 10.2 to 17.4 mm at 200 mgmL; 8.2 to 12.6 mm at 100 mgmL; and 9.2 to 9.8 mm at 50 mgmL. Klebsiella pneumoniae 10.2 mm at 200 mgmL was the least susceptible to the extract, while Bacillus subtilis 17.4 mm at 200 mgmL was the most sensitive. The extracts minimum inhibitory concentration MIC against Staphylococcus aureus, B. subtilis, and K. pneumoniae ranged between 25 mgmL and 200 mgmL. For B. subtilis, S. aureus, and Pseudomonas aeruginosa, the minimum bactericidal concentration MBC of the extract was recorded at 50 mgmL and 200 mgmL, respectively; however, no MBC was found for K. pneumoniae. S. aureus exhibited the highest level of resistance 70, while P. aeruginosa demonstrated the lowest level of resistance 10. Pefloxacin, ciprofloxacin, septrin, and sparfloxacin were identified as the most potent antibiotics. The findings suggest that L. sulphureus has potential as an antibacterial agent, though its effectiveness varies according to extract concentration and bacterial species.

 Ethanol extracts from Laetiporus sulphureus Bull. Murrill Polyporaceae were tested for their antibacterial activity against multidrug-resistant bacterial isolates using agar well diffusion and dilution procedures. According to the findings, L. sulphureuss antibacterial activity differed depending on the extract concentration. While no activity was observed at other dosages, the ethanolic extract demonstrated inhibitory zones ranging from 10.2 to 17.4 mm at 200 mgmL; 8.2 to 12.6 mm at 100 mgmL; and 9.2 to 9.8 mm at 50 mgmL. Klebsiella pneumoniae 10.2 mm at 200 mgmL was the least susceptible to the extract, while Bacillus subtilis 17.4 mm at 200 mgmL was the most sensitive. The extracts minimum inhibitory concentration MIC against Staphylococcus aureus, B. subtilis, and K. pneumoniae ranged between 25 mgmL and 200 mgmL. For B. subtilis, S. aureus, and Pseudomonas aeruginosa, the minimum bactericidal concentration MBC of the extract was recorded at 50 mgmL and 200 mgmL, respectively; however, no MBC was found for K. pneumoniae. S. aureus exhibited the highest level of resistance 70, while P. aeruginosa demonstrated the lowest level of resistance 10. Pefloxacin, ciprofloxacin, septrin, and sparfloxacin were identified as the most potent antibiotics. The findings suggest that L. sulphureus has potential as an antibacterial agent, though its effectiveness varies according to extract concentration and bacterial species.

 Laetiporus sulphureus Bull. Murrill Polyporaceae etanol ekstraktlarının, çoklu ilaca dirençli bakteri izolatlarına karşı antibakteriyel aktivitesi agar kuyucuk difüzyon ve dilüsyon yöntemleri kullanılarak test edilmiştir. Bulgulara göre, L. sulphureusun antibakteriyel aktivitesi ekstrakt konsantrasyonuna bağlı olarak değişiklik göstermektedir. Diğer dozlarda aktivite gözlenmezken, etanolik ekstrakt 200 mgmLde 10,2 ile 17,4 mm arasında, 100 mgmLde 8,2 ile 12,6 mm arasında ve 50 mgmLde 9,2 ile 9,8 mm arasında inhibisyon zonları göstermiştir. Ekstrakta en az duyarlı bakteri 200 mgmLde 10,2 mm ile Klebsiella pneumoniae iken, en duyarlı bakteri 200 mgmLde 17,4 mm ile Bacillus subtilis olmuştur. Ekstraktın Staphylococcus aureus, B. subtilis ve K. pneumoniaeye karşı minimum inhibitör konsantrasyonu MİK 25 mgmL ile 200 mgmL arasında değişmektedir. B. subtilis, S. aureus ve Pseudomonas aeruginosa için ekstraktın minimum bakterisidal konsantrasyonu MBK sırasıyla 50 mgmL ve 200 mgmL olarak kaydedilmiştir; ancak K. pneumoniae için herhangi bir MBK bulunamamıştır. S. aureus en yüksek direnç seviyesini 70 gösterirken, P. aeruginosa en düşük direnç seviyesini 10 göstermiştir. Pefloksasin, siprofloksasin, septrin ve sparfloksasin en güçlü antibiyotikler olarak tanımlanmıştır. Bulgular, L. sulphureusun bir antibakteriyel ajan olarak potansiyel taşıdığını, ancak etkinliğinin ekstrakt konsantrasyonuna ve bakteri türüne göre değiştiğini göstermektedir.

Makale detayları

Antibacterial Activity of Laetiporus sulphureus Extracts Against Multidrug Resistant Bacterial Isolates

Yazarlar:

Ayşegül Akkoyunlu | Gorkem Dulger | Başaran Dülger

Yayıncı:

Selcuk University

Ana Başlıklar:

Mikoloji

Dergi:

Mantar Dergisi Vol.16 Issue 1, pp.1-7

Belge Tipi:

Makale

Yayın Tarihi:

4/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001345928

pISSN:

2147-6845

Laetiporus sulphureus

Antibacterial Activity

Multidrug-Resistant Bacterial IsolatesLaetiporus sulphureus

Antibakteriyel Aktivite

Çoklu İlaca Dirençli Bakteri İzolatları

Sayı

Makale detayları

Antibacterial Activity of Laetiporus sulphureus Extracts Against Multidrug Resistant Bacterial Isolates

Yazarlar: Ayşegül Akkoyunlu | Gorkem Dulger | Başaran Dülger

Yayıncı: Selcuk University

Ana Başlıklar: Mikoloji

Dergi: Mantar Dergisi Vol.16 Issue 1, pp.1-7

Belge Tipi: Makale

Yayın Tarihi: 4/2025

Belge Dili: İngilizce

Document ID (Org No.): 2001345928

pISSN: 2147-6845

Laetiporus sulphureus

Antibacterial Activity

Multidrug-Resistant Bacterial IsolatesLaetiporus sulphureus

Antibakteriyel Aktivite

Çoklu İlaca Dirençli Bakteri İzolatları

Sayı

Yazarlar:

Ayşegül Akkoyunlu | Gorkem Dulger | Başaran Dülger

Yayıncı:

Selcuk University

Ana Başlıklar:

Mikoloji

Dergi:

Mantar Dergisi Vol.16 Issue 1, pp.1-7

Belge Tipi:

Makale

Yayın Tarihi:

4/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001345928

pISSN:

2147-6845