Evaluation of biological activities of onion from Turkey and determination of phytochemical contents

Sezen Yılmaz Sarıaltın; Ekin Kurtul; Müjde Eryilmaz; Büşra Yaylacı; Tülay Çoban; Özlem Bahadır Acıkara

Makale detayları

Evaluation of biological activities of onion from Turkey and determination of phytochemical contents

Yazarlar:

Sezen Yılmaz Sarıaltın | Ekin Kurtul | Müjde Eryilmaz | Büşra Yaylacı | Tülay Çoban | Özlem Bahadır Acıkara

Yayıncı:

Marmara University

Ana Başlıklar:

Pharmacognosy

Dergi:

Journal of Research in Pharmacy Vol.25 Issue 5, pp.554-563

Belge Tipi:

Makale

Yayın Tarihi:

6/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001346221

pISSN:

2630-6344

Anahtar kelimeler:

Özet:

 Allium cepa L. belonging to Amaryllidaceae, is considered to be one of the most cultivated and consumed vegetable in the world. Besides nutritional value, as medicinal usage has also been reported. Onion has been cultivated widely and used as a vegetable mainly, in Turkey. Treatment of wounds, abscess, hemorrhoids, arteriosclerosis, gynecological problems, urinary inflammation, headache, cough by usage of onion and its diuretic and hypoglycemic activities are recorded in Turkish folk medicine. In this study, antimicrobial, antioxidant, anti-inflammatory activities and total phenolic-flavonoid contents of red, white and yellow onion samples from Ankara-Turkey, were investigated. The peels and tissues of onion samples were extracted by sonication with 80 ethanol at room temperature. Phytochemical contents were investigated by High Performance Liquid Chromatography. The highest amount of quercetin was detected in red onion peel 0.3169 mg100 mg; and protocatechuic acid in yellow onion peel 0.3492 mg100 mg. Determining the antimicrobial activities against Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, Pseudomonas aeruginosa by using microbroth dilution method, peel extracts exhibited higher activity than tissues. Yellow onion peel displayed the best 2,2-azino bis 3-ethylbenzothiazoline-6-sulphonic acid and 2,2-diphenyl-l-picrylhydrazyl scavenging activity IC500.0125 and 0.0433 mgml, respectively and also human red blood cell membrane stabilization activity which was used as a marker of anti-inflammatory activity IC500.5363 mgml. Supporting these biological activities, the highest flavonoid content was determined in yellow onion peel 186.9250 mg QEg crude extract. Additionally, red onion peel displayed the highest superoxide anion radical scavenging activity IC500.0987 mgml. All results have revealed that peel extracts possessed higher activity than tissues.

 Allium cepa L. belonging to Amaryllidaceae, is considered to be one of the most cultivated and consumed vegetable in the world. Besides nutritional value, as medicinal usage has also been reported. Onion has been cultivated widely and used as a vegetable mainly, in Turkey. Treatment of wounds, abscess, hemorrhoids, arteriosclerosis, gynecological problems, urinary inflammation, headache, cough by usage of onion and its diuretic and hypoglycemic activities are recorded in Turkish folk medicine. In this study, antimicrobial, antioxidant, anti-inflammatory activities and total phenolic-flavonoid contents of red, white and yellow onion samples from Ankara-Turkey, were investigated. The peels and tissues of onion samples were extracted by sonication with 80 ethanol at room temperature. Phytochemical contents were investigated by High Performance Liquid Chromatography. The highest amount of quercetin was detected in red onion peel 0.3169 mg100 mg; and protocatechuic acid in yellow onion peel 0.3492 mg100 mg. Determining the antimicrobial activities against Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, Pseudomonas aeruginosa by using microbroth dilution method, peel extracts exhibited higher activity than tissues. Yellow onion peel displayed the best 2,2-azino bis 3-ethylbenzothiazoline-6-sulphonic acid and 2,2-diphenyl-l-picrylhydrazyl scavenging activity IC500.0125 and 0.0433 mgml, respectively and also human red blood cell membrane stabilization activity which was used as a marker of anti-inflammatory activity IC500.5363 mgml. Supporting these biological activities, the highest flavonoid content was determined in yellow onion peel 186.9250 mg QEg crude extract. Additionally, red onion peel displayed the highest superoxide anion radical scavenging activity IC500.0987 mgml. All results have revealed that peel extracts possessed higher activity than tissues.

 Allium cepa L. belonging to Amaryllidaceae, is considered to be one of the most cultivated and consumed vegetable in the world. Besides nutritional value, as medicinal usage has also been reported. Onion has been cultivated widely and used as a vegetable mainly, in Turkey. Treatment of wounds, abscess, hemorrhoids, arteriosclerosis, gynecological problems, urinary inflammation, headache, cough by usage of onion and its diuretic and hypoglycemic activities are recorded in Turkish folk medicine. In this study, antimicrobial, antioxidant, anti-inflammatory activities and total phenolic-flavonoid contents of red, white and yellow onion samples from Ankara-Turkey, were investigated. The peels and tissues of onion samples were extracted by sonication with 80 ethanol at room temperature. Phytochemical contents were investigated by High Performance Liquid Chromatography. The highest amount of quercetin was detected in red onion peel 0.3169 mg100 mg; and protocatechuic acid in yellow onion peel 0.3492 mg100 mg. Determining the antimicrobial activities against Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, Pseudomonas aeruginosa by using microbroth dilution method, peel extracts exhibited higher activity than tissues. Yellow onion peel displayed the best 2,2-azino bis 3-ethylbenzothiazoline-6-sulphonic acid and 2,2-diphenyl-l-picrylhydrazyl scavenging activity IC500.0125 and 0.0433 mgml, respectively and also human red blood cell membrane stabilization activity which was used as a marker of anti-inflammatory activity IC500.5363 mgml. Supporting these biological activities, the highest flavonoid content was determined in yellow onion peel 186.9250 mg QEg crude extract. Additionally, red onion peel displayed the highest superoxide anion radical scavenging activity IC500.0987 mgml. All results have revealed that peel extracts possessed higher activity than tissues.

 Allium cepa L. belonging to Amaryllidaceae, is considered to be one of the most cultivated and consumed vegetable in the world. Besides nutritional value, as medicinal usage has also been reported. Onion has been cultivated widely and used as a vegetable mainly, in Turkey. Treatment of wounds, abscess, hemorrhoids, arteriosclerosis, gynecological problems, urinary inflammation, headache, cough by usage of onion and its diuretic and hypoglycemic activities are recorded in Turkish folk medicine. In this study, antimicrobial, antioxidant, anti-inflammatory activities and total phenolic-flavonoid contents of red, white and yellow onion samples from Ankara-Turkey, were investigated. The peels and tissues of onion samples were extracted by sonication with 80 ethanol at room temperature. Phytochemical contents were investigated by High Performance Liquid Chromatography. The highest amount of quercetin was detected in red onion peel 0.3169 mg100 mg; and protocatechuic acid in yellow onion peel 0.3492 mg100 mg. Determining the antimicrobial activities against Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, Pseudomonas aeruginosa by using microbroth dilution method, peel extracts exhibited higher activity than tissues. Yellow onion peel displayed the best 2,2-azino bis 3-ethylbenzothiazoline-6-sulphonic acid and 2,2-diphenyl-l-picrylhydrazyl scavenging activity IC500.0125 and 0.0433 mgml, respectively and also human red blood cell membrane stabilization activity which was used as a marker of anti-inflammatory activity IC500.5363 mgml. Supporting these biological activities, the highest flavonoid content was determined in yellow onion peel 186.9250 mg QEg crude extract. Additionally, red onion peel displayed the highest superoxide anion radical scavenging activity IC500.0987 mgml. All results have revealed that peel extracts possessed higher activity than tissues.

Makale detayları

Evaluation of biological activities of onion from Turkey and determination of phytochemical contents

Yazarlar:

Sezen Yılmaz Sarıaltın | Ekin Kurtul | Müjde Eryilmaz | Büşra Yaylacı | Tülay Çoban | Özlem Bahadır Acıkara

Yayıncı:

Marmara University

Ana Başlıklar:

Pharmacognosy

Dergi:

Journal of Research in Pharmacy Vol.25 Issue 5, pp.554-563

Belge Tipi:

Makale

Yayın Tarihi:

6/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001346221

pISSN:

2630-6344

Allium cepa

anti-inflammatory activity

antimicrobial activity

antioxidant activity

Sayı

Makale detayları

Evaluation of biological activities of onion from Turkey and determination of phytochemical contents

Yazarlar: Sezen Yılmaz Sarıaltın | Ekin Kurtul | Müjde Eryilmaz | Büşra Yaylacı | Tülay Çoban | Özlem Bahadır Acıkara

Yayıncı: Marmara University

Ana Başlıklar: Pharmacognosy

Dergi: Journal of Research in Pharmacy Vol.25 Issue 5, pp.554-563

Belge Tipi: Makale

Yayın Tarihi: 6/2025

Belge Dili: İngilizce

Document ID (Org No.): 2001346221

pISSN: 2630-6344

Allium cepa

anti-inflammatory activity

antimicrobial activity

antioxidant activity

Sayı

Yazarlar:

Sezen Yılmaz Sarıaltın | Ekin Kurtul | Müjde Eryilmaz | Büşra Yaylacı | Tülay Çoban | Özlem Bahadır Acıkara

Yayıncı:

Marmara University

Ana Başlıklar:

Pharmacognosy

Dergi:

Journal of Research in Pharmacy Vol.25 Issue 5, pp.554-563

Belge Tipi:

Makale

Yayın Tarihi:

6/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001346221

pISSN:

2630-6344