Design, Fabrication and Performance Analysis of a Portable, Antenna Analyzer Based, Quartz Crystal Microbalance Measuring System with Energy Dissipation

Ceyhun Ekrem Kirimli

Makale detayları

Design, Fabrication and Performance Analysis of a Portable, Antenna Analyzer Based, Quartz Crystal Microbalance Measuring System with Energy Dissipation

Yazarlar:

Ceyhun Ekrem Kirimli

Yayıncı:

Fırat University

Ana Başlıklar:

Biyomedikal Tanı | Tıbbi Cihazlar

Dergi:

Fırat Üniversitesi Mühendislik Bilimleri Dergisi Vol.36 Issue 1, pp.437-445

Belge Tipi:

Makale

Yayın Tarihi:

3/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001302455

pISSN:

1308-9072

Anahtar kelimeler:

Özet:

 Impedance measurements play a critical role in analyzing the electrical behavior of piezoelectric biosensors in general. Antenna analyzers are engineered to measure the specific case of input impedance for antenna systems. In this study small form factor antenna analyzer is repurposed to work as driving circuit for a Quartz Crystal Microbalance QCM biosensor in combination with a single board computer as an indication of how small and portable an impedance measuring system can be made, while allowing monitoring of important parameters of series and parallel resonance frequencies together with dissipation factor. A QCM crystal with a 10 MHz fundamental resonance frequency is employed to determine the limit of detection of the system in Bovine Serum Albumin BSA and glycerol solutions. Dissipation factor and phase angle were monitored during the experiments. Limit of detection is 20 µgml BSA in phosphate buffer saline PBS and 250 µl of glycerol in 100 ml of deionized water.

 Impedance measurements play a critical role in analyzing the electrical behavior of piezoelectric biosensors in general. Antenna analyzers are engineered to measure the specific case of input impedance for antenna systems. In this study small form factor antenna analyzer is repurposed to work as driving circuit for a Quartz Crystal Microbalance QCM biosensor in combination with a single board computer as an indication of how small and portable an impedance measuring system can be made, while allowing monitoring of important parameters of series and parallel resonance frequencies together with dissipation factor. A QCM crystal with a 10 MHz fundamental resonance frequency is employed to determine the limit of detection of the system in Bovine Serum Albumin BSA and glycerol solutions. Dissipation factor and phase angle were monitored during the experiments. Limit of detection is 20 µgml BSA in phosphate buffer saline PBS and 250 µl of glycerol in 100 ml of deionized water.

 Impedance measurements play a critical role in analyzing the electrical behavior of piezoelectric biosensors in general. Antenna analyzers are engineered to measure the specific case of input impedance for antenna systems. In this study small form factor antenna analyzer is repurposed to work as driving circuit for a Quartz Crystal Microbalance QCM biosensor in combination with a single board computer as an indication of how small and portable an impedance measuring system can be made, while allowing monitoring of important parameters of series and parallel resonance frequencies together with dissipation factor. A QCM crystal with a 10 MHz fundamental resonance frequency is employed to determine the limit of detection of the system in Bovine Serum Albumin BSA and glycerol solutions. Dissipation factor and phase angle were monitored during the experiments. Limit of detection is 20 µgml BSA in phosphate buffer saline PBS and 250 µl of glycerol in 100 ml of deionized water.

 Empedans ölçümü birçok piezoelektrik biyosensörün elektriksel davranışını analiz etmede kritik rol oynayan bir tekniktir. Anten analizörleri, anten sistemlerinin giriş empedansını ölçmek için tasarlanmıştır. Bu çalışmada bir empedans ölçüm sisteminin ne kadar küçük ve taşınabilir olabileceğinin bir kanıtı olarak, tek kartlı bir bilgisayarla kombinasyon halinde bir Kuvars Kristal Mikro Terazi QCM biyosensörü için sürüş devresi olarak çalışmak üzere küçük form faktörlü bir anten analizörü yeniden tasarlanmiştır. Seri ve paralel rezonans frekanslarının ve dağılım faktörünün önemli parametrelerinin izlenmesi 10 MHz temel rezonans frekansına sahip bir QCM kristali, sistemin Bovine Serum Albumin BSA ve Gliserol çözeltilerinde tespit limitini belirlemiştir. Deneyler sırasında dağılım faktörü ve faz açısı izlenmiştir. Saptama sınırı, fosfat tamponlu salinde PBS 20 µgml BSA ve 100 ml deiyonize suda 250 µl gliseroldür.

Makale detayları

Design, Fabrication and Performance Analysis of a Portable, Antenna Analyzer Based, Quartz Crystal Microbalance Measuring System with Energy Dissipation

Yazarlar:

Ceyhun Ekrem Kirimli

Yayıncı:

Fırat University

Ana Başlıklar:

Biyomedikal Tanı | Tıbbi Cihazlar

Dergi:

Fırat Üniversitesi Mühendislik Bilimleri Dergisi Vol.36 Issue 1, pp.437-445

Belge Tipi:

Makale

Yayın Tarihi:

3/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001302455

pISSN:

1308-9072

Quartz Crystal Microbalance

dissipation factor

phase angle

Bovine Serum Albumin

impedance measurementKuvars Kristal Mikroterazi

enerji yitim faktörü

faz açısı

sığır serum albümini

empedans ölçümü

Sayı

Makale detayları

Yazarlar: Ceyhun Ekrem Kirimli

Yayıncı: Fırat University

Ana Başlıklar: Biyomedikal Tanı | Tıbbi Cihazlar

Dergi: Fırat Üniversitesi Mühendislik Bilimleri Dergisi Vol.36 Issue 1, pp.437-445

Belge Tipi: Makale

Yayın Tarihi: 3/2024

Belge Dili: İngilizce

Document ID (Org No.): 2001302455

pISSN: 1308-9072

Sayı

Yazarlar:

Ceyhun Ekrem Kirimli

Yayıncı:

Fırat University

Ana Başlıklar:

Biyomedikal Tanı | Tıbbi Cihazlar

Dergi:

Fırat Üniversitesi Mühendislik Bilimleri Dergisi Vol.36 Issue 1, pp.437-445

Belge Tipi:

Makale

Yayın Tarihi:

3/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001302455

pISSN:

1308-9072