Effect of treatment of iron deficiency anemia onhemoglobin A1c in type 2 diabetic patients

Ensieh NASLI-ESFAHANI; Bagher LARIJANI; Peyvand AMINI; Robabeh Ghodsi GHASEMABADI; Rezvan RAZMANDEH

Makale detayları

Effect of treatment of iron deficiency anemia onhemoglobin A1c in type 2 diabetic patients

Yazarlar:

Ensieh NASLI-ESFAHANI | Bagher LARIJANI | Peyvand AMINI | Robabeh Ghodsi GHASEMABADI | Rezvan RAZMANDEH

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 2017 Vol.47 Issue 5, pp.1441-1446

Belge Tipi:

Makale

Yayın Tarihi:

9/2017

Belge Dili:

Türkçe

Document ID (Org No.):

2000751105

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144

Özet:

 

Background/aim: Iron deficiency anemia (IDA) affects hemoglobin A1c (HbA1c) levels. This study aimed to evaluate the effect of treatment of iron deficiency anemia on hemoglobin A1c in type 2 diabetic patients.Materials and methods: Ninety type 2 diabetes mellitus (T2DM) patients with IDA were included in a randomized, placebo-controlled, single-blind clinical trial. The intervention group (n = 45) received 200 mg/day oral iron for 3 months and the control group (n = 45) received an oral placebo for the same period. Fasting blood sugar, complete blood count, and HbA1c were measured for all subjects at the beginning and the end of the trial.Results: The mean age of the treatment and control group was 51.47 ±±\pm 1.05 and 52 ±±\pm 1.1 years, respectively. The two groups were not statistically significantly different with regard to diabetes duration (P = 0.436) and age (P = 0.617). Hemoglobin, mean corpuscular volume, mean corpuscular hemoglobin, serum iron, ferritin, total iron-binding capacity, and HbA1c were significantly improved in the intervention group in comparison with the control group (P = 0.005).Conclusion: Iron status should be considered during the interpretation of the HbA1c concentrations in diabetes mellitus. Iron replacement therapy can decrease HbA1c in anemic patients with IDA and T2DM.

Makale detayları

Effect of treatment of iron deficiency anemia onhemoglobin A1c in type 2 diabetic patients

Yazarlar: Ensieh NASLI-ESFAHANI | Bagher LARIJANI | Peyvand AMINI | Robabeh Ghodsi GHASEMABADI | Rezvan RAZMANDEH

Yayıncı: TUBITAK

Dergi: Turkish Journal of Medical Sciences 2017 Vol.47 Issue 5, pp.1441-1446

Belge Tipi: Makale

Yayın Tarihi: 9/2017

Belge Dili: Türkçe

Document ID (Org No.): 2000751105

Sıklık: İki Aylık

eISSN: 1303-6165

pISSN: 1300-0144

Sayı

Yazarlar:

Ensieh NASLI-ESFAHANI | Bagher LARIJANI | Peyvand AMINI | Robabeh Ghodsi GHASEMABADI | Rezvan RAZMANDEH

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 2017 Vol.47 Issue 5, pp.1441-1446

Belge Tipi:

Makale

Yayın Tarihi:

9/2017

Belge Dili:

Türkçe

Document ID (Org No.):

2000751105

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144