Characterization of clinical features of monosensitized and polysensitized allergic rhinitis patients with pollen allergy

Şadan Soyyiğit; Dilek Öksüzer Çimşir

Makale detayları

Characterization of clinical features of monosensitized and polysensitized allergic rhinitis patients with pollen allergy

Yazarlar:

Şadan Soyyiğit | Dilek Öksüzer Çimşir

Yayıncı:

Prusa Medical Publishing

Ana Başlıklar:

Allergy

Dergi:

The European Research Journal Vol.9 Issue 5, pp.884-893

Belge Tipi:

Makale

Yayın Tarihi:

4/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001288102

pISSN:

2149-3189

Anahtar kelimeler:

Özet:

 Objectives: The present study evaluates the prevalence of monosensitization and polysensitization in patients with pollen-hypersensitive moderate-to-severe persistent allergic rhinitis AR, and determines the clinical characteristics of the two phenotypes. Methods: This retrospective cohort study included 160 patients with moderate-to-severe persistent AR among the 3,699 patients who presented to allergy outpatient clinics who were found to have hypersensitivity to pollen based on a skin prick test andor allergen-specific IgE positivity. The patients were divided into two groups: monosensitized hypersensitivity to pollen alone, and polysensitized hypersensitivity to pollen and other allergens. Both groups were evaluated for allergen hypersensitivity, symptoms of AR, symptom frequency and comorbidities related to AR. Results: Of the 160 patients, 83 51.9 were monosensitized and 77 48.1 were polysensitized. The mean age was 29.5  10.7 yeasrs and 28.3  8.3 years, respectively and the female-to-male ratio was 4241 and 4730 in the two groups. Nasal congestion was remarkably more common in the polysensitized patients than in the monosensitized patients  p  0.01. Hypersensitivity to weed mix and Cupressus arizonica pollen identified with a skin prick test was significantly more common in the polysensitized patients than in the monosensitized patients  p  0.03 and p  0.01, respectively. The two groups were similar in terms of the prevalence of asthma and other comorbidities related to rhinitis  p  0.78. Conclusions: In this single-center study, the rates of monosensitization and polysensitization were found to be similar in patients with pollen-hypersensitive moderate-to-severe AR, and the clinical characteristics of the polysensitized phenotype were different from those of the monosensitized phenotype.

 Objectives: The present study evaluates the prevalence of monosensitization and polysensitization in patients with pollen-hypersensitive moderate-to-severe persistent allergic rhinitis AR, and determines the clinical characteristics of the two phenotypes. Methods: This retrospective cohort study included 160 patients with moderate-to-severe persistent AR among the 3,699 patients who presented to allergy outpatient clinics who were found to have hypersensitivity to pollen based on a skin prick test andor allergen-specific IgE positivity. The patients were divided into two groups: monosensitized hypersensitivity to pollen alone, and polysensitized hypersensitivity to pollen and other allergens. Both groups were evaluated for allergen hypersensitivity, symptoms of AR, symptom frequency and comorbidities related to AR. Results: Of the 160 patients, 83 51.9 were monosensitized and 77 48.1 were polysensitized. The mean age was 29.5  10.7 yeasrs and 28.3  8.3 years, respectively and the female-to-male ratio was 4241 and 4730 in the two groups. Nasal congestion was remarkably more common in the polysensitized patients than in the monosensitized patients  p  0.01. Hypersensitivity to weed mix and Cupressus arizonica pollen identified with a skin prick test was significantly more common in the polysensitized patients than in the monosensitized patients  p  0.03 and p  0.01, respectively. The two groups were similar in terms of the prevalence of asthma and other comorbidities related to rhinitis  p  0.78. Conclusions: In this single-center study, the rates of monosensitization and polysensitization were found to be similar in patients with pollen-hypersensitive moderate-to-severe AR, and the clinical characteristics of the polysensitized phenotype were different from those of the monosensitized phenotype.

 Objectives: The present study evaluates the prevalence of monosensitization and polysensitization in patients with pollen-hypersensitive moderate-to-severe persistent allergic rhinitis AR, and determines the clinical characteristics of the two phenotypes. Methods: This retrospective cohort study included 160 patients with moderate-to-severe persistent AR among the 3,699 patients who presented to allergy outpatient clinics who were found to have hypersensitivity to pollen based on a skin prick test andor allergen-specific IgE positivity. The patients were divided into two groups: monosensitized hypersensitivity to pollen alone, and polysensitized hypersensitivity to pollen and other allergens. Both groups were evaluated for allergen hypersensitivity, symptoms of AR, symptom frequency and comorbidities related to AR. Results: Of the 160 patients, 83 51.9 were monosensitized and 77 48.1 were polysensitized. The mean age was 29.5  10.7 yeasrs and 28.3  8.3 years, respectively and the female-to-male ratio was 4241 and 4730 in the two groups. Nasal congestion was remarkably more common in the polysensitized patients than in the monosensitized patients  p  0.01. Hypersensitivity to weed mix and Cupressus arizonica pollen identified with a skin prick test was significantly more common in the polysensitized patients than in the monosensitized patients  p  0.03 and p  0.01, respectively. The two groups were similar in terms of the prevalence of asthma and other comorbidities related to rhinitis  p  0.78. Conclusions: In this single-center study, the rates of monosensitization and polysensitization were found to be similar in patients with pollen-hypersensitive moderate-to-severe AR, and the clinical characteristics of the polysensitized phenotype were different from those of the monosensitized phenotype.

 Objectives: The present study evaluates the prevalence of monosensitization and polysensitization in patients with pollen-hypersensitive moderate-to-severe persistent allergic rhinitis AR, and determines the clinical characteristics of the two phenotypes. Methods: This retrospective cohort study included 160 patients with moderate-to-severe persistent AR among the 3,699 patients who presented to allergy outpatient clinics who were found to have hypersensitivity to pollen based on a skin prick test andor allergen-specific IgE positivity. The patients were divided into two groups: monosensitized hypersensitivity to pollen alone, and polysensitized hypersensitivity to pollen and other allergens. Both groups were evaluated for allergen hypersensitivity, symptoms of AR, symptom frequency and comorbidities related to AR. Results: Of the 160 patients, 83 51.9 were monosensitized and 77 48.1 were polysensitized. The mean age was 29.5  10.7 yeasrs and 28.3  8.3 years, respectively and the female-to-male ratio was 4241 and 4730 in the two groups. Nasal congestion was remarkably more common in the polysensitized patients than in the monosensitized patients  p  0.01. Hypersensitivity to weed mix and Cupressus arizonica pollen identified with a skin prick test was significantly more common in the polysensitized patients than in the monosensitized patients  p  0.03 and p  0.01, respectively. The two groups were similar in terms of the prevalence of asthma and other comorbidities related to rhinitis  p  0.78. Conclusions: In this single-center study, the rates of monosensitization and polysensitization were found to be similar in patients with pollen-hypersensitive moderate-to-severe AR, and the clinical characteristics of the polysensitized phenotype were different from those of the monosensitized phenotype.

Makale detayları

Characterization of clinical features of monosensitized and polysensitized allergic rhinitis patients with pollen allergy

Yazarlar:

Şadan Soyyiğit | Dilek Öksüzer Çimşir

Yayıncı:

Prusa Medical Publishing

Ana Başlıklar:

Allergy

Dergi:

The European Research Journal Vol.9 Issue 5, pp.884-893

Belge Tipi:

Makale

Yayın Tarihi:

4/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001288102

pISSN:

2149-3189

Pollen allergy

allergic rhinitis

monosensitization

polysensitization

skin prick test

Sayı

Makale detayları

Characterization of clinical features of monosensitized and polysensitized allergic rhinitis patients with pollen allergy

Yazarlar: Şadan Soyyiğit | Dilek Öksüzer Çimşir

Yayıncı: Prusa Medical Publishing

Ana Başlıklar: Allergy

Dergi: The European Research Journal Vol.9 Issue 5, pp.884-893

Belge Tipi: Makale

Yayın Tarihi: 4/2023

Belge Dili: İngilizce

Document ID (Org No.): 2001288102

pISSN: 2149-3189

Pollen allergy

allergic rhinitis

monosensitization

polysensitization

skin prick test

Sayı

Yazarlar:

Şadan Soyyiğit | Dilek Öksüzer Çimşir

Yayıncı:

Prusa Medical Publishing

Ana Başlıklar:

Allergy

Dergi:

The European Research Journal Vol.9 Issue 5, pp.884-893

Belge Tipi:

Makale

Yayın Tarihi:

4/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001288102

pISSN:

2149-3189