A Unique Case of Intranasal Metastasis from Occult Poorly Differentiated Thyroid Carcinoma

Rauf Oğuzhan KUM; Erdinç AYGENÇ; Battal Tahsin SOMUK; Pelin BÖRCEK; Cafer ÖZDEM

Makale detayları

A Unique Case of Intranasal Metastasis from Occult Poorly Differentiated Thyroid Carcinoma

Yazarlar:

Rauf Oğuzhan KUM | Erdinç AYGENÇ | Battal Tahsin SOMUK | Pelin BÖRCEK | Cafer ÖZDEM

Yayıncı:

Trakya University

Dergi:

Balkan Medical Journal 2015 Vol.32 Issue 3, pp.316-319

Belge Tipi:

Makale

Yayın Tarihi:

6/2015

Belge Dili:

Türkçe

Document ID (Org No.):

2000759833

Sıklık:

İki Aylık

pISSN:

2146-3123

Özet:

 

_Poorly differentiated thyroid carcinomas (PDTCs) lie, both morphologically and behaviorally, between well-differentiated and undifferentiated carcinomas. Metastasis of poorly differentiated thyroid carcinoma to the intranasal cavity has not been reported previously in the literature.     Case Report_ A 48-year-old male patient presented with massive epistaxis and nasal obstruction.  On nasal examination, a bleeding, vascular mass was seen filling the left nasal cavity. The histopathological report of the nasal mass was well-differentiated thyroid carcinoma metastasis. Whole body scintigraphy, ultrasonography and positron emission tomography were done to rule out other possible metastases in the body and determine the origin of the tumor, which was identified as the left lobe of the thyroid gland, and there were multiple metastases involving the lung, sacroiliac area, and left humerus. Histopathological examination of a thyroidectomy specimen revealed PDTC consisting of insular, follicular, and papillary components. Postoperatively, the patient received radioactive iodine ablation therapy (iodine-131) and a course of external beam radiation therapy to the sacroiliac area and other metastatic regions. No recurrences were observed in a follow-up period of 5 years after surgery.     Conclusion_ The metastasis of differentiated thyroid carcinoma as a component of PDTC to the intranasal cavity has not been reported before. It is interesting that the well-differentiated component of the tumor was metastasized in our patient. Due to the aggressiveness of PDTC and the poor survival rates in patients who undergo surgery alone, a multidisciplinary treatment approach is required_.

Makale detayları

A Unique Case of Intranasal Metastasis from Occult Poorly Differentiated Thyroid Carcinoma

Yazarlar: Rauf Oğuzhan KUM | Erdinç AYGENÇ | Battal Tahsin SOMUK | Pelin BÖRCEK | Cafer ÖZDEM

Yayıncı: Trakya University

Dergi: Balkan Medical Journal 2015 Vol.32 Issue 3, pp.316-319

Belge Tipi: Makale

Yayın Tarihi: 6/2015

Belge Dili: Türkçe

Document ID (Org No.): 2000759833

Sıklık: İki Aylık

pISSN: 2146-3123

Sayı

Yazarlar:

Rauf Oğuzhan KUM | Erdinç AYGENÇ | Battal Tahsin SOMUK | Pelin BÖRCEK | Cafer ÖZDEM

Yayıncı:

Trakya University

Dergi:

Balkan Medical Journal 2015 Vol.32 Issue 3, pp.316-319

Belge Tipi:

Makale

Yayın Tarihi:

6/2015

Belge Dili:

Türkçe

Document ID (Org No.):

2000759833

Sıklık:

İki Aylık

pISSN:

2146-3123