Synthesis and Antimicrobial Activity of Some Pyridyl and Naphthyl Substituted 1,2,4-Triazole and 1,3,4-Thiadiazole Derivatives

Khosrow ZAMANI; Khalil FAGHIHI; Taraneh TOFIGHI

Makale detayları

Synthesis and Antimicrobial Activity of Some Pyridyl and Naphthyl Substituted 1,2,4-Triazole and 1,3,4-Thiadiazole Derivatives

Yazarlar:

Khosrow ZAMANI | Khalil FAGHIHI | Taraneh TOFIGHI

Yayıncı:

TUBITAK

Ana Başlıklar:

Uygulamalı fizik

Dergi:

Turkish Journal of Chemistry 2004 Vol.28 Issue 1, pp.95-100

Belge Tipi:

Makale

Yayın Tarihi:

12/2003

Belge Dili:

İngilizce

Document ID (Org No.):

2000729423

Sıklık:

İki Aylık

eISSN:

1303-6130

pISSN:

1300-0527

Özet:

 

Synthesis of new 1,2,4-tri and 1,3,4-thiadiazoles, bearing  isomeric pyridyl and 1-naphthyl is reported using 1,4-disubstituted  thiosemicarbazides in alkaline and acidic media, respectively.  The  methylthio and benzylthio derivatives of the synthesized triazoles are  also reported.  All of the synthesized compounds were characterized by  their FT-IR, 1H-NMR and mass spectral data.  The antibacterial  studies of some of the synthesized compounds against S. aureus} and E.  coli} as MIC values are reported.  None of them have important  antibacterial activities.

 

Synthesis of new 1,2,4-tri and 1,3,4-thiadiazoles, bearing  isomeric pyridyl and 1-naphthyl is reported using 1,4-disubstituted  thiosemicarbazides in alkaline and acidic media, respectively.  The  methylthio and benzylthio derivatives of the synthesized triazoles are  also reported.  All of the synthesized compounds were characterized by  their FT-IR, 1H-NMR and mass spectral data.  The antibacterial  studies of some of the synthesized compounds against S. aureus} and E.  coli} as MIC values are reported.  None of them have important  antibacterial activities.

Makale detayları

Synthesis and Antimicrobial Activity of Some Pyridyl and Naphthyl Substituted 1,2,4-Triazole and 1,3,4-Thiadiazole Derivatives

Yazarlar: Khosrow ZAMANI | Khalil FAGHIHI | Taraneh TOFIGHI

Yayıncı: TUBITAK

Ana Başlıklar: Uygulamalı fizik

Dergi: Turkish Journal of Chemistry 2004 Vol.28 Issue 1, pp.95-100

Belge Tipi: Makale

Yayın Tarihi: 12/2003

Belge Dili: İngilizce

Document ID (Org No.): 2000729423

Sıklık: İki Aylık

eISSN: 1303-6130

pISSN: 1300-0527

Sayı

Yazarlar:

Khosrow ZAMANI | Khalil FAGHIHI | Taraneh TOFIGHI

Yayıncı:

TUBITAK

Ana Başlıklar:

Uygulamalı fizik

Dergi:

Turkish Journal of Chemistry 2004 Vol.28 Issue 1, pp.95-100

Belge Tipi:

Makale

Yayın Tarihi:

12/2003

Belge Dili:

İngilizce

Document ID (Org No.):

2000729423

Sıklık:

İki Aylık

eISSN:

1303-6130

pISSN:

1300-0527