Is There an Association between First Trimester 25-Hydroxy Vitamin D Levels and Gestational Diabetes Mellitus?

Samet Kırat

Makale detayları

Is There an Association between First Trimester 25-Hydroxy Vitamin D Levels and Gestational Diabetes Mellitus?

Yazarlar:

Samet Kırat

Yayıncı:

Kafkas University

Ana Başlıklar:

Klinik Tıp Bilimleri (Diğer)

Dergi:

Kafkas Tıp Bilimleri Dergisi Vol.14 Issue 3, pp.260-266

Belge Tipi:

Makale

Yayın Tarihi:

12/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001337787

pISSN:

2146-2631

Anahtar kelimeler:

Özet:

 Aim: Pregnant women have high Vitamin D deficiency rates. Some studies have suggested that vitamin D deficiency is associated with gestational diabetes mellitus GDM. This study aimed to investigate the association between first trimester 25-hydroxy vitamin D levels and the risk of developing GDM. Material and Method: A retrospective analysis was conducted on 409 pregnant women aged 1850 years with singleton pregnancies who had their 25OH vitamin D levels checked in the first trimester and underwent an oral glucose tolerance test OGTT between 24 28 weeks of gestation. Demographic data, 25OH vitamin D levels, and OGTT results were recorded. Gestational diabetes mellitus was diagnosed according to the criteria of the International Association of Diabetes and Pregnancy Study Groups IADPSG criteria. Vitamin D levels were categorized into deficiency 20 ng ml, insufficiency 2030 ngml, and adequacy 30 ngml. Results: The median age of the participants was 33 years, and 24.6 n101 had GDM. The median 25OH vitamin D level was 18 ngml, and deficiency was found in 57.2 n234, insufficiency in 34.2 n140, and adequate level in 8.6 n35. The median age 32 vs 34 years; p0.008, smoking rate 18.8 vs. 8.4; p0.007, and median 25OH vitamin D level 10430 ng ml vs 20 3151 ngml; p0.001 were significantly lower in patients with GDM than in those without GDM. 25OH vitamin D 12 ngml aOR: 0.086, 95 C. I.: 0.510.144, p0.001 and 25OH vitamin D 20 ngml aOR: 0.073, 95 C. I.: 0.0340.155, p0.001 were strongly associated with GDM in logistic regression analysis. Conclusion: The risk of GDM can be minimized by regular vitamin D supplementation at prophylactic doses before pregnancy.

 Aim: Pregnant women have high Vitamin D deficiency rates. Some studies have suggested that vitamin D deficiency is associated with gestational diabetes mellitus GDM. This study aimed to investigate the association between first trimester 25-hydroxy vitamin D levels and the risk of developing GDM. Material and Method: A retrospective analysis was conducted on 409 pregnant women aged 1850 years with singleton pregnancies who had their 25OH vitamin D levels checked in the first trimester and underwent an oral glucose tolerance test OGTT between 24 28 weeks of gestation. Demographic data, 25OH vitamin D levels, and OGTT results were recorded. Gestational diabetes mellitus was diagnosed according to the criteria of the International Association of Diabetes and Pregnancy Study Groups IADPSG criteria. Vitamin D levels were categorized into deficiency 20 ng ml, insufficiency 2030 ngml, and adequacy 30 ngml. Results: The median age of the participants was 33 years, and 24.6 n101 had GDM. The median 25OH vitamin D level was 18 ngml, and deficiency was found in 57.2 n234, insufficiency in 34.2 n140, and adequate level in 8.6 n35. The median age 32 vs 34 years; p0.008, smoking rate 18.8 vs. 8.4; p0.007, and median 25OH vitamin D level 10430 ng ml vs 20 3151 ngml; p0.001 were significantly lower in patients with GDM than in those without GDM. 25OH vitamin D 12 ngml aOR: 0.086, 95 C. I.: 0.510.144, p0.001 and 25OH vitamin D 20 ngml aOR: 0.073, 95 C. I.: 0.0340.155, p0.001 were strongly associated with GDM in logistic regression analysis. Conclusion: The risk of GDM can be minimized by regular vitamin D supplementation at prophylactic doses before pregnancy.

 Aim: Pregnant women have high Vitamin D deficiency rates. Some studies have suggested that vitamin D deficiency is associated with gestational diabetes mellitus GDM. This study aimed to investigate the association between first trimester 25-hydroxy vitamin D levels and the risk of developing GDM. Material and Method: A retrospective analysis was conducted on 409 pregnant women aged 1850 years with singleton pregnancies who had their 25OH vitamin D levels checked in the first trimester and underwent an oral glucose tolerance test OGTT between 24 28 weeks of gestation. Demographic data, 25OH vitamin D levels, and OGTT results were recorded. Gestational diabetes mellitus was diagnosed according to the criteria of the International Association of Diabetes and Pregnancy Study Groups IADPSG criteria. Vitamin D levels were categorized into deficiency 20 ng ml, insufficiency 2030 ngml, and adequacy 30 ngml. Results: The median age of the participants was 33 years, and 24.6 n101 had GDM. The median 25OH vitamin D level was 18 ngml, and deficiency was found in 57.2 n234, insufficiency in 34.2 n140, and adequate level in 8.6 n35. The median age 32 vs 34 years; p0.008, smoking rate 18.8 vs. 8.4; p0.007, and median 25OH vitamin D level 10430 ng ml vs 20 3151 ngml; p0.001 were significantly lower in patients with GDM than in those without GDM. 25OH vitamin D 12 ngml aOR: 0.086, 95 C. I.: 0.510.144, p0.001 and 25OH vitamin D 20 ngml aOR: 0.073, 95 C. I.: 0.0340.155, p0.001 were strongly associated with GDM in logistic regression analysis. Conclusion: The risk of GDM can be minimized by regular vitamin D supplementation at prophylactic doses before pregnancy.

 Aim: Pregnant women have high Vitamin D deficiency rates. Some studies have suggested that vitamin D deficiency is associated with gestational diabetes mellitus GDM. This study aimed to investigate the association between first trimester 25-hydroxy vitamin D levels and the risk of developing GDM. Material and Method: A retrospective analysis was conducted on 409 pregnant women aged 1850 years with singleton pregnancies who had their 25OH vitamin D levels checked in the first trimester and underwent an oral glucose tolerance test OGTT between 24 28 weeks of gestation. Demographic data, 25OH vitamin D levels, and OGTT results were recorded. Gestational diabetes mellitus was diagnosed according to the criteria of the International Association of Diabetes and Pregnancy Study Groups IADPSG criteria. Vitamin D levels were categorized into deficiency 20 ng ml, insufficiency 2030 ngml, and adequacy 30 ngml. Results: The median age of the participants was 33 years, and 24.6 n101 had GDM. The median 25OH vitamin D level was 18 ngml, and deficiency was found in 57.2 n234, insufficiency in 34.2 n140, and adequate level in 8.6 n35. The median age 32 vs 34 years; p0.008, smoking rate 18.8 vs. 8.4; p0.007, and median 25OH vitamin D level 10430 ng ml vs 20 3151 ngml; p0.001 were significantly lower in patients with GDM than in those without GDM. 25OH vitamin D 12 ngml aOR: 0.086, 95 C. I.: 0.510.144, p0.001 and 25OH vitamin D 20 ngml aOR: 0.073, 95 C. I.: 0.0340.155, p0.001 were strongly associated with GDM in logistic regression analysis. Conclusion: The risk of GDM can be minimized by regular vitamin D supplementation at prophylactic doses before pregnancy.

Makale detayları

Is There an Association between First Trimester 25-Hydroxy Vitamin D Levels and Gestational Diabetes Mellitus?

Yazarlar:

Samet Kırat

Yayıncı:

Kafkas University

Ana Başlıklar:

Klinik Tıp Bilimleri (Diğer)

Dergi:

Kafkas Tıp Bilimleri Dergisi Vol.14 Issue 3, pp.260-266

Belge Tipi:

Makale

Yayın Tarihi:

12/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001337787

pISSN:

2146-2631

vitamin D deficiency

gestasyonel diabetes mellitus

oral glucose tolerance test

Sayı

Makale detayları

Is There an Association between First Trimester 25-Hydroxy Vitamin D Levels and Gestational Diabetes Mellitus?

Yazarlar: Samet Kırat

Yayıncı: Kafkas University

Ana Başlıklar: Klinik Tıp Bilimleri (Diğer)

Dergi: Kafkas Tıp Bilimleri Dergisi Vol.14 Issue 3, pp.260-266

Belge Tipi: Makale

Yayın Tarihi: 12/2024

Belge Dili: İngilizce

Document ID (Org No.): 2001337787

pISSN: 2146-2631

vitamin D deficiency

gestasyonel diabetes mellitus

oral glucose tolerance test

Sayı

Yazarlar:

Samet Kırat

Yayıncı:

Kafkas University

Ana Başlıklar:

Klinik Tıp Bilimleri (Diğer)

Dergi:

Kafkas Tıp Bilimleri Dergisi Vol.14 Issue 3, pp.260-266

Belge Tipi:

Makale

Yayın Tarihi:

12/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001337787

pISSN:

2146-2631