ASSESSMENT OF THE RANSON SCORE IN ACUTE PANCREATITIS: ITS VALUE IN AN EMERGENCY SETTING UPON ADMISSION

Naci Şenkal; Latif Karahan; Ali Emre Bardak; Hilal Konyaoğlu; Ebru Teberik Kama; Leman Damla Ercan; Alpay Medetalibeyoğlu; Tufan Tükek

Makale detayları

ASSESSMENT OF THE RANSON SCORE IN ACUTE PANCREATITIS: ITS VALUE IN AN EMERGENCY SETTING UPON ADMISSION

Yazarlar:

Naci Şenkal | Latif Karahan | Ali Emre Bardak | Hilal Konyaoğlu | Ebru Teberik Kama | Leman Damla Ercan | Alpay Medetalibeyoğlu | Tufan Tükek

Yayıncı:

Istanbul University

Ana Başlıklar:

Sağlık Hizmetleri ve Sistemleri (Diğer)

Dergi:

İstanbul Tıp Fakültesi Dergisi Vol.86 Issue 3, pp.198-203

Belge Tipi:

Makale

Yayın Tarihi:

10/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001293738

pISSN:

1305-6441

Anahtar kelimeler:

Özet:

 Objective: Ranson criteria, introduced in 1974, was the first clinical prediction rule for acute pancreatitis in which five admission parameters and six or five late components collected within 48 hours were used to reach a clinical decision. This 48- hour follow-up requirement was not convenient for use in the Emergency Department setting. This study was undertaken to assess whether five admission Ranson parameters may have use in differentiating edematous pancreatitis from necrotizing pancreatitis in the emergency department setting. Material and Method: Patient data for this retrospective cohortstudy was gathered from 205 patients treated for acute pancreatitis from January 2018 to December 2022 in a tertiary care center. The patient files were extracted from the archives for clinical data gathering. Laboratory admission data and radiology reports were extracted from the automated laboratory reporting system. Result: The 205 acute pancreatitis patients were mostly female and in their sixth decade. The etiology was mostly biliary pancreatitis 76. Patient history revealed that 80 was the first attack. The radiologic imaging study review revealed the majority of the patients had edematous pancreatitis 87. Higher scores in admission Ranson score aRS weakly predicted increasingly higher probability 2.6 for aRS 0 to 28.6 for aRS 4-5 for the presence of necrosis without reaching statistical significance p0.055 When components of the score were analyzed, age, LDH levels, and glucose had no discriminating value, WBC parameter posi tivity significantly increased the odds of necrotizing pancreatitis, whereas positive AST level significantly decreased the risk of necrotizing pancreatitis. Conclusion: In conclusion, aRS had little utility in predicting pancreatic necrosis.

 Objective: Ranson criteria, introduced in 1974, was the first clinical prediction rule for acute pancreatitis in which five admission parameters and six or five late components collected within 48 hours were used to reach a clinical decision. This 48- hour follow-up requirement was not convenient for use in the Emergency Department setting. This study was undertaken to assess whether five admission Ranson parameters may have use in differentiating edematous pancreatitis from necrotizing pancreatitis in the emergency department setting. Material and Method: Patient data for this retrospective cohortstudy was gathered from 205 patients treated for acute pancreatitis from January 2018 to December 2022 in a tertiary care center. The patient files were extracted from the archives for clinical data gathering. Laboratory admission data and radiology reports were extracted from the automated laboratory reporting system. Result: The 205 acute pancreatitis patients were mostly female and in their sixth decade. The etiology was mostly biliary pancreatitis 76. Patient history revealed that 80 was the first attack. The radiologic imaging study review revealed the majority of the patients had edematous pancreatitis 87. Higher scores in admission Ranson score aRS weakly predicted increasingly higher probability 2.6 for aRS 0 to 28.6 for aRS 4-5 for the presence of necrosis without reaching statistical significance p0.055 When components of the score were analyzed, age, LDH levels, and glucose had no discriminating value, WBC parameter posi tivity significantly increased the odds of necrotizing pancreatitis, whereas positive AST level significantly decreased the risk of necrotizing pancreatitis. Conclusion: In conclusion, aRS had little utility in predicting pancreatic necrosis.

 Objective: Ranson criteria, introduced in 1974, was the first clinical prediction rule for acute pancreatitis in which five admission parameters and six or five late components collected within 48 hours were used to reach a clinical decision. This 48- hour follow-up requirement was not convenient for use in the Emergency Department setting. This study was undertaken to assess whether five admission Ranson parameters may have use in differentiating edematous pancreatitis from necrotizing pancreatitis in the emergency department setting. Material and Method: Patient data for this retrospective cohortstudy was gathered from 205 patients treated for acute pancreatitis from January 2018 to December 2022 in a tertiary care center. The patient files were extracted from the archives for clinical data gathering. Laboratory admission data and radiology reports were extracted from the automated laboratory reporting system. Result: The 205 acute pancreatitis patients were mostly female and in their sixth decade. The etiology was mostly biliary pancreatitis 76. Patient history revealed that 80 was the first attack. The radiologic imaging study review revealed the majority of the patients had edematous pancreatitis 87. Higher scores in admission Ranson score aRS weakly predicted increasingly higher probability 2.6 for aRS 0 to 28.6 for aRS 4-5 for the presence of necrosis without reaching statistical significance p0.055 When components of the score were analyzed, age, LDH levels, and glucose had no discriminating value, WBC parameter posi tivity significantly increased the odds of necrotizing pancreatitis, whereas positive AST level significantly decreased the risk of necrotizing pancreatitis. Conclusion: In conclusion, aRS had little utility in predicting pancreatic necrosis.

 Amaç: 1974te tanıtılan Ranson kriterleri, klinik bir karara varmak için 48 saat içinde toplanan 5 kabul parametresi ve 6 veya 5 geç bileşenin kullanıldığı akut pankreatit için ilk klinik tahmin kuralıydı. Bu 48 saatlik takip gerekliliği, Acil Servis ortamında kullanım için uygun değildi. Bu çalışma, acil servis ortamında ödematöz pankreatitin nekrotizan pankreatitten ayırt edilmesinde 5 kabul Ranson parametresinin kullanılıp kullanılamayacağını değerlendirmek için yapılmıştır. Gereç ve Yöntem: Bu retrospektif kohort çalışması için hasta verileri, üçüncü basamak bir bakım merkezinde Ocak 2018 ile Aralık 2022 arasında akut pankreatit nedeniyle tedavi edilen 205 hastadan toplandı. Hasta dosyaları, klinik veri toplamak için arşivlerden çıkarıldı. Laboratuvar kabul verileri ve radyoloji raporları otomatik laboratuvar raporlama sisteminden alınmıştır. Bulgular: 205 akut pankreatit hastasının çoğu kadındı ve altıncı dekattaydı. Etiyoloji çoğunlukla biliyer pankreatit 76 idi. Hastaöyküsü, 80inin ilk atak olduğunu ortaya koydu. Radyolojik görüntüleme çalışması incelemesi, hastaların çoğunda 87 ödematöz pankreatit olduğunu ortaya çıkardı. Başvurudaki daha yüksek Ranson skoru aRS, istatistiksel anlamlılığa ulaşmadan p0.055 nekroz varlığı için daha yüksek bir olasılığı aRS 0 için 2.6 ila aRS 4-5 için 28.6 zayıf şekilde öngördü. Skorun bileşenleri analiz edildiğinde, yaş, LDH düzeyleri ve glukozun ayırt edici bir değeri yoktu, WBC parametresinin pozitifliği nekrotizan pankreatit olasılığını önemli ölçüde artırırken, pozitif AST düzeyi nekrotizan pankreatit riskini önemli ölçüde azalttı. Sonuç: Sonuç olarak, aRSnin pankreas nekrozunu tahmin etmede çok az faydası vardı.

Makale detayları

ASSESSMENT OF THE RANSON SCORE IN ACUTE PANCREATITIS: ITS VALUE IN AN EMERGENCY SETTING UPON ADMISSION

Yazarlar:

Naci Şenkal | Latif Karahan | Ali Emre Bardak | Hilal Konyaoğlu | Ebru Teberik Kama | Leman Damla Ercan | Alpay Medetalibeyoğlu | Tufan Tükek

Yayıncı:

Istanbul University

Ana Başlıklar:

Sağlık Hizmetleri ve Sistemleri (Diğer)

Dergi:

İstanbul Tıp Fakültesi Dergisi Vol.86 Issue 3, pp.198-203

Belge Tipi:

Makale

Yayın Tarihi:

10/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001293738

pISSN:

1305-6441

Ranson score

acute pancreatitis

necrotizing pancreatitis

edematous pancreatitisRanson skoru

akut pankreatit

nekrotizan pankreatit

ödematöz pankreatit

Sayı

Makale detayları

Yazarlar: Naci Şenkal | Latif Karahan | Ali Emre Bardak | Hilal Konyaoğlu | Ebru Teberik Kama | Leman Damla Ercan | Alpay Medetalibeyoğlu | Tufan Tükek

Yayıncı: Istanbul University

Ana Başlıklar: Sağlık Hizmetleri ve Sistemleri (Diğer)

Dergi: İstanbul Tıp Fakültesi Dergisi Vol.86 Issue 3, pp.198-203

Belge Tipi: Makale

Yayın Tarihi: 10/2023

Belge Dili: İngilizce

Document ID (Org No.): 2001293738

pISSN: 1305-6441

Sayı

Yazarlar:

Naci Şenkal | Latif Karahan | Ali Emre Bardak | Hilal Konyaoğlu | Ebru Teberik Kama | Leman Damla Ercan | Alpay Medetalibeyoğlu | Tufan Tükek

Yayıncı:

Istanbul University

Ana Başlıklar:

Sağlık Hizmetleri ve Sistemleri (Diğer)

Dergi:

İstanbul Tıp Fakültesi Dergisi Vol.86 Issue 3, pp.198-203

Belge Tipi:

Makale

Yayın Tarihi:

10/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001293738

pISSN:

1305-6441