Investigation of Plantago lanceolata L.: a multidimensional study on its biochemical profiling, antioxidant capacity, and biological activities

Melike Ersin; Elif Gönül; Ezginur Duman; Gizem Gül; Dilay Turu; Atakan Benek; Kerem Canlı

Makale detayları

Investigation of Plantago lanceolata L.: a multidimensional study on its biochemical profiling, antioxidant capacity, and biological activities

Yazarlar:

Melike Ersin | Elif Gönül | Ezginur Duman | Gizem Gül | Dilay Turu | Atakan Benek | Kerem Canlı

Yayıncı:

Ankara University

Ana Başlıklar:

Botany (Other)

Dergi:

Communications Faculty of Sciences University of Ankara Series C Biology Vol.34 Issue 1, pp.76-103

Belge Tipi:

Makale

Yayın Tarihi:

6/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001350845

pISSN:

1303-6025

Anahtar kelimeler:

Özet:

 Plantago lanceolata L. is a medicinal and aromatic plant recognized for its antimicrobial and antioxidant effects. This research focused on evaluating its biological activity, antioxidant capacity, and volatile compound composition through Gas Chromatography-Mass Spectrometry GC-MS analysis. The extracts effects on biofilms formed by pathogenic bacteria were evaluated, showing significant biofilm inhibition and disruption. The antimicrobial activity was assessed based on minimum inhibitory concentration MIC and minimum bactericidal concentration MBC values. The extract exhibited strong effects against Staphylococcus aureus MRSA, Streptococcus mutans, and S. aureus MRSAMDR strains. The antioxidant potential was assessed through the 1,1-Diphenyl-2-picrylhydrazyl DPPH radical assay, demonstrating a notable ability to scavenge free radicals. These findings suggest that P. lanceolata could serve as a protective or supportive agent against diseases associated with oxidative stress. GC-MS analysis identified the volatile components, with high concentrations of fatty acid derivatives such as linolenic acid and hexadecenoic acid. The study demonstrated that P. lanceolata possesses notable antibiofilm, antimicrobial, and antioxidant properties, making it a valuable natural resource. Owing to its bioactive compounds, this species exhibits significant potential for applications in the pharmaceutical, food, and cosmetic industries. It may also function as an important phytochemical in the drug developers search for resources. Further research is required to expand its potential applications and prove its clinical efficacy.

 Plantago lanceolata L. is a medicinal and aromatic plant recognized for its antimicrobial and antioxidant effects. This research focused on evaluating its biological activity, antioxidant capacity, and volatile compound composition through Gas Chromatography-Mass Spectrometry GC-MS analysis. The extracts effects on biofilms formed by pathogenic bacteria were evaluated, showing significant biofilm inhibition and disruption. The antimicrobial activity was assessed based on minimum inhibitory concentration MIC and minimum bactericidal concentration MBC values. The extract exhibited strong effects against Staphylococcus aureus MRSA, Streptococcus mutans, and S. aureus MRSAMDR strains. The antioxidant potential was assessed through the 1,1-Diphenyl-2-picrylhydrazyl DPPH radical assay, demonstrating a notable ability to scavenge free radicals. These findings suggest that P. lanceolata could serve as a protective or supportive agent against diseases associated with oxidative stress. GC-MS analysis identified the volatile components, with high concentrations of fatty acid derivatives such as linolenic acid and hexadecenoic acid. The study demonstrated that P. lanceolata possesses notable antibiofilm, antimicrobial, and antioxidant properties, making it a valuable natural resource. Owing to its bioactive compounds, this species exhibits significant potential for applications in the pharmaceutical, food, and cosmetic industries. It may also function as an important phytochemical in the drug developers search for resources. Further research is required to expand its potential applications and prove its clinical efficacy.

 Plantago lanceolata L. is a medicinal and aromatic plant recognized for its antimicrobial and antioxidant effects. This research focused on evaluating its biological activity, antioxidant capacity, and volatile compound composition through Gas Chromatography-Mass Spectrometry GC-MS analysis. The extracts effects on biofilms formed by pathogenic bacteria were evaluated, showing significant biofilm inhibition and disruption. The antimicrobial activity was assessed based on minimum inhibitory concentration MIC and minimum bactericidal concentration MBC values. The extract exhibited strong effects against Staphylococcus aureus MRSA, Streptococcus mutans, and S. aureus MRSAMDR strains. The antioxidant potential was assessed through the 1,1-Diphenyl-2-picrylhydrazyl DPPH radical assay, demonstrating a notable ability to scavenge free radicals. These findings suggest that P. lanceolata could serve as a protective or supportive agent against diseases associated with oxidative stress. GC-MS analysis identified the volatile components, with high concentrations of fatty acid derivatives such as linolenic acid and hexadecenoic acid. The study demonstrated that P. lanceolata possesses notable antibiofilm, antimicrobial, and antioxidant properties, making it a valuable natural resource. Owing to its bioactive compounds, this species exhibits significant potential for applications in the pharmaceutical, food, and cosmetic industries. It may also function as an important phytochemical in the drug developers search for resources. Further research is required to expand its potential applications and prove its clinical efficacy.

 Plantago lanceolata L. is a medicinal and aromatic plant recognized for its antimicrobial and antioxidant effects. This research focused on evaluating its biological activity, antioxidant capacity, and volatile compound composition through Gas Chromatography-Mass Spectrometry GC-MS analysis. The extracts effects on biofilms formed by pathogenic bacteria were evaluated, showing significant biofilm inhibition and disruption. The antimicrobial activity was assessed based on minimum inhibitory concentration MIC and minimum bactericidal concentration MBC values. The extract exhibited strong effects against Staphylococcus aureus MRSA, Streptococcus mutans, and S. aureus MRSAMDR strains. The antioxidant potential was assessed through the 1,1-Diphenyl-2-picrylhydrazyl DPPH radical assay, demonstrating a notable ability to scavenge free radicals. These findings suggest that P. lanceolata could serve as a protective or supportive agent against diseases associated with oxidative stress. GC-MS analysis identified the volatile components, with high concentrations of fatty acid derivatives such as linolenic acid and hexadecenoic acid. The study demonstrated that P. lanceolata possesses notable antibiofilm, antimicrobial, and antioxidant properties, making it a valuable natural resource. Owing to its bioactive compounds, this species exhibits significant potential for applications in the pharmaceutical, food, and cosmetic industries. It may also function as an important phytochemical in the drug developers search for resources. Further research is required to expand its potential applications and prove its clinical efficacy.

Makale detayları

Investigation of Plantago lanceolata L.: a multidimensional study on its biochemical profiling, antioxidant capacity, and biological activities

Yazarlar:

Melike Ersin | Elif Gönül | Ezginur Duman | Gizem Gül | Dilay Turu | Atakan Benek | Kerem Canlı

Yayıncı:

Ankara University

Ana Başlıklar:

Botany (Other)

Dergi:

Communications Faculty of Sciences University of Ankara Series C Biology Vol.34 Issue 1, pp.76-103

Belge Tipi:

Makale

Yayın Tarihi:

6/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001350845

pISSN:

1303-6025

Plantago lanceolata L.

anti-biofilm activity

antimicrobial activity

antioxidant activity

Sayı

Makale detayları

Investigation of Plantago lanceolata L.: a multidimensional study on its biochemical profiling, antioxidant capacity, and biological activities

Yazarlar: Melike Ersin | Elif Gönül | Ezginur Duman | Gizem Gül | Dilay Turu | Atakan Benek | Kerem Canlı

Yayıncı: Ankara University

Ana Başlıklar: Botany (Other)

Dergi: Communications Faculty of Sciences University of Ankara Series C Biology Vol.34 Issue 1, pp.76-103

Belge Tipi: Makale

Yayın Tarihi: 6/2025

Belge Dili: İngilizce

Document ID (Org No.): 2001350845

pISSN: 1303-6025

Plantago lanceolata L.

anti-biofilm activity

antimicrobial activity

antioxidant activity

Sayı

Yazarlar:

Melike Ersin | Elif Gönül | Ezginur Duman | Gizem Gül | Dilay Turu | Atakan Benek | Kerem Canlı

Yayıncı:

Ankara University

Ana Başlıklar:

Botany (Other)

Dergi:

Communications Faculty of Sciences University of Ankara Series C Biology Vol.34 Issue 1, pp.76-103

Belge Tipi:

Makale

Yayın Tarihi:

6/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001350845

pISSN:

1303-6025