Genomic Imprinting: A Specialized Form of Gene  Regulation

Fatma Filiz COŞKUN-ARI

Makale detayları

Genomic Imprinting: A Specialized Form of Gene Regulation

Yazarlar:

Fatma Filiz COŞKUN-ARI

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Biology 2000 Vol.24 Issue 2, pp.241-252

Belge Tipi:

Makale

Yayın Tarihi:

1/2000

Belge Dili:

Türkçe

Document ID (Org No.):

2000814066

Sıklık:

İki Aylık

eISSN:

1303-6092

pISSN:

1300-0152

Anahtar kelimeler:

Özet:

 

Genomic imprinting is a process resulting in the preferential expression of certain genes  depending on whether the genetic material has been inherited from the mother or the father. Many  imprinted genes have been identified as having important roles in mammalian development, and the  loss of imprints as well as non-imprinted alleles causes a variety of developmental abnormalities and  pathological conditions in both mice and humans. In this article, the phenomenon of genomic  imprinting, the developmental implications of imprinting and the molecular mechanisms proposed for  this process are reviewed.

 

Genomic imprinting is a process resulting in the preferential expression of certain genes  depending on whether the genetic material has been inherited from the mother or the father. Many  imprinted genes have been identified as having important roles in mammalian development, and the  loss of imprints as well as non-imprinted alleles causes a variety of developmental abnormalities and  pathological conditions in both mice and humans. In this article, the phenomenon of genomic  imprinting, the developmental implications of imprinting and the molecular mechanisms proposed for  this process are reviewed.

Makale detayları

Genomic Imprinting: A Specialized Form of Gene Regulation

Yazarlar:

Fatma Filiz COŞKUN-ARI

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Biology 2000 Vol.24 Issue 2, pp.241-252

Belge Tipi:

Makale

Yayın Tarihi:

1/2000

Belge Dili:

Türkçe

Document ID (Org No.):

2000814066

Sıklık:

İki Aylık

eISSN:

1303-6092

pISSN:

1300-0152

Genomic imprinting

Preferential gene expression

Gene regulation

Sayı

Makale detayları

Genomic Imprinting: A Specialized Form of Gene Regulation

Yazarlar: Fatma Filiz COŞKUN-ARI

Yayıncı: TUBITAK

Dergi: Turkish Journal of Biology 2000 Vol.24 Issue 2, pp.241-252

Belge Tipi: Makale

Yayın Tarihi: 1/2000

Belge Dili: Türkçe

Document ID (Org No.): 2000814066

Sıklık: İki Aylık

eISSN: 1303-6092

pISSN: 1300-0152

Genomic imprinting

Preferential gene expression

Gene regulation

Sayı

Yazarlar:

Fatma Filiz COŞKUN-ARI

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Biology 2000 Vol.24 Issue 2, pp.241-252

Belge Tipi:

Makale

Yayın Tarihi:

1/2000

Belge Dili:

Türkçe

Document ID (Org No.):

2000814066

Sıklık:

İki Aylık

eISSN:

1303-6092

pISSN:

1300-0152