The Effects of Some Anaesthetics on the Electrocardiograms of Guinea Pigs

İlksin PİŞKİN; Meltem ŞİRELİ; Vedat SAĞMANLIGİL; Bahri EMRE

Makale detayları

The Effects of Some Anaesthetics on the Electrocardiograms of Guinea Pigs

Yazarlar:

İlksin PİŞKİN | Meltem ŞİRELİ | Vedat SAĞMANLIGİL | Bahri EMRE

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Veterinary and Animal Sciences 1999 Vol.23 Issue EK1, pp.161-166

Belge Tipi:

Makale

Yayın Tarihi:

11/1998

Belge Dili:

Türkçe

Document ID (Org No.):

2000772400

Sıklık:

İki Aylık

eISSN:

1303-6181

pISSN:

1300-0128

Anahtar kelimeler:

Özet:

 

This study was carried out to observe the effects on electrocardiography of using droperidol-fentanyl and ketamine-xylazine combinations, urethane and pentothal sodium as anaesthetic doses.  In this study, thirty-five 4-5 months-old quinea pigs of both sexes weighing 540-600 g were used. The quinea pigs were divided equally into 5 groups. The first group was used as the control group and nothing was given to this group. The combination of droperidol (20 mg/ml)-fentanyl (0.4 mg/ml) in a dose of 0.8 ml/kg b.wt., was intramuscularly injected into the second group. The combination of ketamine-xylazine was intramuscularly injected into the third group in doses of 0.8 ml/kg and 35 mg/kg b.wt. and 0.2 mg/kg b.wt. respectively. The solutions of 30% urethane for the forth group and 2.5% pentothal sodium  for the fifth group were intraperitoneally injected in doses of 0.5 g/kg b.wt. and 2.5 mg/kg b.w. respectively.  Electrocardiograms were recorded on bipolar extremity leads (I, II and III). The quantitative measurements namely: heart rates, amplitudes of the P, R, S and T waves, the durations of the P and T waves, the QRS complex and finally the durations of the PR and QT intervals were evaluated from lead II. In addition the electrical axis of the QRS complex was obtained from leads I and III.   The duration of the P wave was prolonged while its amplitude was decreased with the combination of ketamine-xylazine. However, any effects on the P wave caused by the others were not observed.  All the anaesthetics except pentobarbiton sodium prolonged the duration of the PR and QT interval and decreased the heart rates. In contrast to this, all decreased the duration of the QRS complex, but the decrease caused by urethane was not signifnanty different from that of the control group.  One of the observed results was that the electrical axis of the QRS complex was not affected by the anaesthetics.  As a conclusion, it was observed that the combinations of droperidol-fentonyl and ketamine-xylazine had clear effects but urethane and pentothal had only limited effects on the ECG.

 

This study was carried out to observe the effects on electrocardiography of using droperidol-fentanyl and ketamine-xylazine combinations, urethane and pentothal sodium as anaesthetic doses.  In this study, thirty-five 4-5 months-old quinea pigs of both sexes weighing 540-600 g were used. The quinea pigs were divided equally into 5 groups. The first group was used as the control group and nothing was given to this group. The combination of droperidol (20 mg/ml)-fentanyl (0.4 mg/ml) in a dose of 0.8 ml/kg b.wt., was intramuscularly injected into the second group. The combination of ketamine-xylazine was intramuscularly injected into the third group in doses of 0.8 ml/kg and 35 mg/kg b.wt. and 0.2 mg/kg b.wt. respectively. The solutions of 30% urethane for the forth group and 2.5% pentothal sodium  for the fifth group were intraperitoneally injected in doses of 0.5 g/kg b.wt. and 2.5 mg/kg b.w. respectively.  Electrocardiograms were recorded on bipolar extremity leads (I, II and III). The quantitative measurements namely: heart rates, amplitudes of the P, R, S and T waves, the durations of the P and T waves, the QRS complex and finally the durations of the PR and QT intervals were evaluated from lead II. In addition the electrical axis of the QRS complex was obtained from leads I and III.   The duration of the P wave was prolonged while its amplitude was decreased with the combination of ketamine-xylazine. However, any effects on the P wave caused by the others were not observed.  All the anaesthetics except pentobarbiton sodium prolonged the duration of the PR and QT interval and decreased the heart rates. In contrast to this, all decreased the duration of the QRS complex, but the decrease caused by urethane was not signifnanty different from that of the control group.  One of the observed results was that the electrical axis of the QRS complex was not affected by the anaesthetics.  As a conclusion, it was observed that the combinations of droperidol-fentonyl and ketamine-xylazine had clear effects but urethane and pentothal had only limited effects on the ECG.

Makale detayları

The Effects of Some Anaesthetics on the Electrocardiograms of Guinea Pigs

Yazarlar:

İlksin PİŞKİN | Meltem ŞİRELİ | Vedat SAĞMANLIGİL | Bahri EMRE

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Veterinary and Animal Sciences 1999 Vol.23 Issue EK1, pp.161-166

Belge Tipi:

Makale

Yayın Tarihi:

11/1998

Belge Dili:

Türkçe

Document ID (Org No.):

2000772400

Sıklık:

İki Aylık

eISSN:

1303-6181

pISSN:

1300-0128

Guinea pig

ECG

droperidol-fentanyl

ketamine-xylazine

ürethane

pentothal sodium

Sayı

Makale detayları

The Effects of Some Anaesthetics on the Electrocardiograms of Guinea Pigs

Yazarlar: İlksin PİŞKİN | Meltem ŞİRELİ | Vedat SAĞMANLIGİL | Bahri EMRE

Yayıncı: TUBITAK

Dergi: Turkish Journal of Veterinary and Animal Sciences 1999 Vol.23 Issue EK1, pp.161-166

Belge Tipi: Makale

Yayın Tarihi: 11/1998

Belge Dili: Türkçe

Document ID (Org No.): 2000772400

Sıklık: İki Aylık

eISSN: 1303-6181

pISSN: 1300-0128

Guinea pig

ECG

droperidol-fentanyl

ketamine-xylazine

ürethane

pentothal sodium

Sayı

Yazarlar:

İlksin PİŞKİN | Meltem ŞİRELİ | Vedat SAĞMANLIGİL | Bahri EMRE

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Veterinary and Animal Sciences 1999 Vol.23 Issue EK1, pp.161-166

Belge Tipi:

Makale

Yayın Tarihi:

11/1998

Belge Dili:

Türkçe

Document ID (Org No.):

2000772400

Sıklık:

İki Aylık

eISSN:

1303-6181

pISSN:

1300-0128