Subclinical Inflammation As an Independent Risk Factor for All-Cause Mortality in Patients with Left Main Coronary Artery Disease

Kadriye MEMİÇ SANCAR; Serkan KAHRAMAN; Seda TÜKENMEZ KARAKURT; Meltem TEKİN; Büşra ÇÖREKCİOĞLU; Alkım ATEŞLİ; Hulusi SATILMIŞOĞLU; Gökhan DEMİRCİ; Mustafa YILDIZ

Makale detayları

Subclinical Inflammation As an Independent Risk Factor for All-Cause Mortality in Patients with Left Main Coronary Artery Disease

Yazarlar:

Kadriye MEMİÇ SANCAR | Serkan KAHRAMAN | Seda TÜKENMEZ KARAKURT | Meltem TEKİN | Büşra ÇÖREKCİOĞLU | Alkım ATEŞLİ | Hulusi SATILMIŞOĞLU | Gökhan DEMİRCİ | Mustafa YILDIZ

Yayıncı:

Kartal Koşuyolu Yüksek İhtisas EAH

Ana Başlıklar:

Hastalıklar

Dergi:

Koşuyolu Heart Journal 2022 Vol.25 Issue 1, pp.14-22

Belge Tipi:

Makale

Yayın Tarihi:

4/2022

Belge Dili:

İngilizce

Document ID (Org No.):

2000732088

Sıklık:

Aylık

eISSN:

2149-2980

pISSN:

2149-2972

Özet:

 

Introduction: This study aimed to investigate pre-procedural (Neutrophil to Lymphocyte Ratio) (NLR) in patients with (Left Main Coronary Artery) (LMCA) disease and to identify a relevant NLR value related to mortality after percutaneous intervention in unprotected LMCA disease. 

Patients and Methods: Seventy-one patients diagnosed with unprotected LMCA disease were divided into two groups according to their mortality rates: survivors (n= 56, 78%) and non-survivors (n= 15, 22%). The mean follow-up duration was 26.0 ± 24.8 months, and all-cause mortality was considered as an endpoint. 

Results: The non-survivor group had higher NLR values [3.23 (2.31-4.01) vs. 5.82 (2.92-14.99), p= 0.026] compared to the survivor-group. ROC analysis revealed an NLR cut-off value of 5.24 for predicting all-cause mortality. During follow-up, the group with high NLR values was associated with a significantly higher rate of all-cause mortality rate [6 (10.5%) vs. 9 (64.3%), p< 0.001] compared to the low NLR group. In multivariate analysis, the NLR (OR= 1.695; 95% CI= 1.124-2.556; p= 0.012) was found to be independent predictors of mortality. 

Conclusion: NLR is the independent predictor of all-cause mortality in unprotected LMCA disease. As far as we know, this study is the first study investigating the prognostic value of NLR in patients with unprotected LMCA disease stenting.

Makale detayları

Subclinical Inflammation As an Independent Risk Factor for All-Cause Mortality in Patients with Left Main Coronary Artery Disease

Yazarlar: Kadriye MEMİÇ SANCAR | Serkan KAHRAMAN | Seda TÜKENMEZ KARAKURT | Meltem TEKİN | Büşra ÇÖREKCİOĞLU | Alkım ATEŞLİ | Hulusi SATILMIŞOĞLU | Gökhan DEMİRCİ | Mustafa YILDIZ

Yayıncı: Kartal Koşuyolu Yüksek İhtisas EAH

Ana Başlıklar: Hastalıklar

Dergi: Koşuyolu Heart Journal 2022 Vol.25 Issue 1, pp.14-22

Belge Tipi: Makale

Yayın Tarihi: 4/2022

Belge Dili: İngilizce

Document ID (Org No.): 2000732088

Sıklık: Aylık

eISSN: 2149-2980

pISSN: 2149-2972

Sayı

Yazarlar:

Kadriye MEMİÇ SANCAR | Serkan KAHRAMAN | Seda TÜKENMEZ KARAKURT | Meltem TEKİN | Büşra ÇÖREKCİOĞLU | Alkım ATEŞLİ | Hulusi SATILMIŞOĞLU | Gökhan DEMİRCİ | Mustafa YILDIZ

Yayıncı:

Kartal Koşuyolu Yüksek İhtisas EAH

Ana Başlıklar:

Hastalıklar

Dergi:

Koşuyolu Heart Journal 2022 Vol.25 Issue 1, pp.14-22

Belge Tipi:

Makale

Yayın Tarihi:

4/2022

Belge Dili:

İngilizce

Document ID (Org No.):

2000732088

Sıklık:

Aylık

eISSN:

2149-2980

pISSN:

2149-2972