Carbapenem-resistant Klebsiella pneumonia infection outbreak in a tertiary urology clinic: analysis of influencing factors with a controlled trial

Fuat KIZILAY; Bayram ALİYEV; Adnan ŞİMŞİR; Mustafa Serdar KALEMCİ; Timur KÖSE; Meltem TAŞBAKAN; Hüsnü PULLUKÇU

doi:https://doi.org/10.3906/sag-1909-46

Makale detayları

Carbapenem-resistant Klebsiella pneumonia infection outbreak in a tertiary urology clinic: analysis of influencing factors with a controlled trial

Yazarlar:

Fuat KIZILAY | Bayram ALİYEV | Adnan ŞİMŞİR | Mustafa Serdar KALEMCİ | Timur KÖSE | Meltem TAŞBAKAN | Hüsnü PULLUKÇU

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 2020 Vol.50 Issue 1, pp.239-247

Belge Tipi:

Makale

Yayın Tarihi:

12/2019

Belge Dili:

İngilizce

Document ID (Org No.):

2000749722

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144

DOI:

https://doi.org/10.3906/sag-1909-46

Özet:

 

Background/aim: Carbapenem-resistant Klebsiella pneumoniae  CR-KP  infections encountered in urology patients differentiate from infections  caused  by  other  factors,  both  in  respect  to  prophylaxis  and  treatment  stage,  and  require  a  special  approach.  We  aimed  to  analyse the predisposing factors and the antibiotherapies for CR-KP infection outbreak in a tertiary urology clinic.Materials and methods: There were 75 patients in the CR-KP positive group  Group I  and 146 patients in the CR-KP negative group  Group II . Analysis of the predisposing factors for CR-KP infection and comparison of the reinfection rate and the antibiotherapies in the 2 groups were the endpoints.Results: In the first group, age, comorbidity, previous antibiotic use, and nephrostomy tube rates were higher  P = 0.015, P = 0.001, P = 0.004, and P < 0.001, respectively . In the second group, open urological surgery rate, and the proportion of patients presenting with flank pain, lower urinary tract symptoms, and haematuria were higher  P = 0.029, P < 0.001, P < 0.001, and P = 0.007 . In the first group, the  proportion  of  patients  treated  with  transurethral  bladder  tumour  resection  was  higher,  whereas,  percutaneous  nephrolithotomy  was higher in the second group  P = 0.045 for both . While hospitalization and Foley catheterization duration were longer in the first group  P < 0.001 for both , double J stent and nephrostomy duration were longer in the second group  P < 0.001 and P = 0.005 . Mean leukocyte count at admission was higher in the first group  P < 0.001 .Conclusion: Advanced age, comorbidities, previous antibiotic use, and prolonged Foley catheterization duration are predisposing factors for this infection in the urology department. Two-week administration of combination antibiotic regimens containing carbapenem were effective for the treatment of this infection.

Makale detayları

Carbapenem-resistant Klebsiella pneumonia infection outbreak in a tertiary urology clinic: analysis of influencing factors with a controlled trial

Yazarlar: Fuat KIZILAY | Bayram ALİYEV | Adnan ŞİMŞİR | Mustafa Serdar KALEMCİ | Timur KÖSE | Meltem TAŞBAKAN | Hüsnü PULLUKÇU

Yayıncı: TUBITAK

Dergi: Turkish Journal of Medical Sciences 2020 Vol.50 Issue 1, pp.239-247

Belge Tipi: Makale

Yayın Tarihi: 12/2019

Belge Dili: İngilizce

Document ID (Org No.): 2000749722

Sıklık: İki Aylık

eISSN: 1303-6165

pISSN: 1300-0144

DOI: https://doi.org/10.3906/sag-1909-46

Sayı

Yazarlar:

Fuat KIZILAY | Bayram ALİYEV | Adnan ŞİMŞİR | Mustafa Serdar KALEMCİ | Timur KÖSE | Meltem TAŞBAKAN | Hüsnü PULLUKÇU

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 2020 Vol.50 Issue 1, pp.239-247

Belge Tipi:

Makale

Yayın Tarihi:

12/2019

Belge Dili:

İngilizce

Document ID (Org No.):

2000749722

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144

DOI:

https://doi.org/10.3906/sag-1909-46