Molecularly-imprinted silica nanoparticles for rapid and selective detection of atenolol in artificial urine samples

Adem ZENGİN

doi:https://doi.org/10.51354/mjen.859016

Makale detayları

Molecularly-imprinted silica nanoparticles for rapid and selective detection of atenolol in artificial urine samples

Yazarlar:

Adem ZENGİN

Yayıncı:

Kyrgyz-Turkish Manas University

Ana Başlıklar:

Uygulamalı fizik

Dergi:

MANAS Journal of Engineering 2021 Vol.9 Issue Special 1, pp.43-48

Belge Tipi:

Makale

Yayın Tarihi:

4/2021

Belge Dili:

İngilizce

Document ID (Org No.):

2000527855

Sıklık:

İki Yıllık

eISSN:

1694-7398

pISSN:

1694-7398

DOI:

https://doi.org/10.51354/mjen.859016

Özet:

 

 Herein, a novel molecularly imprinted polymer was synthesized on silica nanoparticles via surface imprinting approach for rapid, sensitive and selective detection of atenolol in artificial urine samples. For this purpose, silica nanoparticles were firstly modified with methacryloxy group for surface initiated polymerization and then, polymerization was carried out in the presence of 2-hydroxyethyl methacrylate (functional monomer), ethylene glycol dimethacrylate (cross-linker), azobisisobutyronitrile (initiator), atenolol (template) and acetonitrile (porogen). The surface characterization of imprinted nanoparticles indicated that a thin polymer layer was grafted on the silica nanoparticles. The rebinding properties of the imprinted nanoparticles were investigated in detail and the results revealed that the imprinted nanoparticles had high adsorption capacity (32.06 mg/g), fast adsorption kinetics (15 min for equilibration), high imprinting factor (4.14) towards atenolol and good regeneration ability. The imprinted nanoparticles were also used as selective sorbent for selective extraction and determination of atenolol in artificial urine samples. The results showed that the proposed method good recovery percentages (98.6 %-100.1%) with low standard deviations (less than 4.4%). It is believed that the atenolol-imprinted silica nanoparticles can be used as an alternative sorbent for selective quantification of atenolol in artificial urine samples.

Makale detayları

Molecularly-imprinted silica nanoparticles for rapid and selective detection of atenolol in artificial urine samples

Yazarlar: Adem ZENGİN

Yayıncı: Kyrgyz-Turkish Manas University

Ana Başlıklar: Uygulamalı fizik

Dergi: MANAS Journal of Engineering 2021 Vol.9 Issue Special 1, pp.43-48

Belge Tipi: Makale

Yayın Tarihi: 4/2021

Belge Dili: İngilizce

Document ID (Org No.): 2000527855

Sıklık: İki Yıllık

eISSN: 1694-7398

pISSN: 1694-7398

DOI: https://doi.org/10.51354/mjen.859016

Sayı

Yazarlar:

Adem ZENGİN

Yayıncı:

Kyrgyz-Turkish Manas University

Ana Başlıklar:

Uygulamalı fizik

Dergi:

MANAS Journal of Engineering 2021 Vol.9 Issue Special 1, pp.43-48

Belge Tipi:

Makale

Yayın Tarihi:

4/2021

Belge Dili:

İngilizce

Document ID (Org No.):

2000527855

Sıklık:

İki Yıllık

eISSN:

1694-7398

pISSN:

1694-7398

DOI:

https://doi.org/10.51354/mjen.859016