Development of natural rubber latex patch infused with Piper nigrum L. extract

N.A.

Makale detayları

Development of natural rubber latex patch infused with Piper nigrum L. extract

Yazarlar:

N.A.

Yayıncı:

Marmara University

Ana Başlıklar:

Pharmaceutical Chemistry

Dergi:

Journal of Research in Pharmacy Vol.28 Issue 3, pp.821-827

Belge Tipi:

Makale

Yayın Tarihi:

6/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001346649

pISSN:

2630-6344

Anahtar kelimeler:

Özet:

 Piper nigrum L. or black pepper is a well-known spice which is also used in herbal medicine. It has been used as a single herb and in a formula to treat many conditions such as muscle pain. This study develops a transdermal patch using natural rubber latex as a base and infused with P.nigrum extract. The physicochemical properties of the prepared patches were optimized with the addition of plasticizers, which are dibutyl phthalate, polyethylene glycol 400 and glycerin. The efficiency of the transdermal patches was evaluated by measuring the releasing profile of piperine, the main active component of P.nigrum. Other physical characteristics were measured by the tensile strength, moisture uptake, swelling rate and erosion rate. In conclusion, the formulation with the additives of dibutyl phthalate and glycerin showed good piperine release profile and mechanical properties.

 Piper nigrum L. or black pepper is a well-known spice which is also used in herbal medicine. It has been used as a single herb and in a formula to treat many conditions such as muscle pain. This study develops a transdermal patch using natural rubber latex as a base and infused with P.nigrum extract. The physicochemical properties of the prepared patches were optimized with the addition of plasticizers, which are dibutyl phthalate, polyethylene glycol 400 and glycerin. The efficiency of the transdermal patches was evaluated by measuring the releasing profile of piperine, the main active component of P.nigrum. Other physical characteristics were measured by the tensile strength, moisture uptake, swelling rate and erosion rate. In conclusion, the formulation with the additives of dibutyl phthalate and glycerin showed good piperine release profile and mechanical properties.

 Piper nigrum L. or black pepper is a well-known spice which is also used in herbal medicine. It has been used as a single herb and in a formula to treat many conditions such as muscle pain. This study develops a transdermal patch using natural rubber latex as a base and infused with P.nigrum extract. The physicochemical properties of the prepared patches were optimized with the addition of plasticizers, which are dibutyl phthalate, polyethylene glycol 400 and glycerin. The efficiency of the transdermal patches was evaluated by measuring the releasing profile of piperine, the main active component of P.nigrum. Other physical characteristics were measured by the tensile strength, moisture uptake, swelling rate and erosion rate. In conclusion, the formulation with the additives of dibutyl phthalate and glycerin showed good piperine release profile and mechanical properties.

 Piper nigrum L. or black pepper is a well-known spice which is also used in herbal medicine. It has been used as a single herb and in a formula to treat many conditions such as muscle pain. This study develops a transdermal patch using natural rubber latex as a base and infused with P.nigrum extract. The physicochemical properties of the prepared patches were optimized with the addition of plasticizers, which are dibutyl phthalate, polyethylene glycol 400 and glycerin. The efficiency of the transdermal patches was evaluated by measuring the releasing profile of piperine, the main active component of P.nigrum. Other physical characteristics were measured by the tensile strength, moisture uptake, swelling rate and erosion rate. In conclusion, the formulation with the additives of dibutyl phthalate and glycerin showed good piperine release profile and mechanical properties.

Makale detayları

Development of natural rubber latex patch infused with Piper nigrum L. extract

Yazarlar:

N.A.

Yayıncı:

Marmara University

Ana Başlıklar:

Pharmaceutical Chemistry

Dergi:

Journal of Research in Pharmacy Vol.28 Issue 3, pp.821-827

Belge Tipi:

Makale

Yayın Tarihi:

6/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001346649

pISSN:

2630-6344

Transdermal patch

Piper nigrum L.

black pepper extract

natural rubber latex

plasticizer

Sayı

Makale detayları

Development of natural rubber latex patch infused with Piper nigrum L. extract

Yazarlar: N.A.

Yayıncı: Marmara University

Ana Başlıklar: Pharmaceutical Chemistry

Dergi: Journal of Research in Pharmacy Vol.28 Issue 3, pp.821-827

Belge Tipi: Makale

Yayın Tarihi: 6/2025

Belge Dili: İngilizce

Document ID (Org No.): 2001346649

pISSN: 2630-6344

Transdermal patch

Piper nigrum L.

black pepper extract

natural rubber latex

plasticizer

Sayı

Yazarlar:

N.A.

Yayıncı:

Marmara University

Ana Başlıklar:

Pharmaceutical Chemistry

Dergi:

Journal of Research in Pharmacy Vol.28 Issue 3, pp.821-827

Belge Tipi:

Makale

Yayın Tarihi:

6/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001346649

pISSN:

2630-6344