Investigation of the Relationship between Clinical Severity of Acne and Inflammatory Parameters in Patients with Acne Vulgaris

Hanife Merve Akça; Kevser Tuncer Kara

Makale detayları

Investigation of the Relationship between Clinical Severity of Acne and Inflammatory Parameters in Patients with Acne Vulgaris

Yazarlar:

Hanife Merve Akça | Kevser Tuncer Kara

Yayıncı:

Ondokuz Mayıs University

Ana Başlıklar:

Health Care Administration

Dergi:

Deneysel ve Klinik Tıp Dergisi Vol.40 Issue 2, pp.205-210

Belge Tipi:

Makale

Yayın Tarihi:

7/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001293694

pISSN:

1309-4483

Anahtar kelimeler:

Özet:

 Objective In this study, we investigated whether the Neutrophil Lymphosite NL ratio, mean platelet volume MPV value, GADS The global acne rating system score and other inflammatory parameters are related in acne vulgaris patients. Methods One-hundred acne patients, aged between 1840 years, who treated at the Karaman Training and Research Hospital Dermatology Polyclinic between January and March 2022 were included in the study. Age, sex, duration of disease, medications and additional systemic diseases were recorded. Acne patients included in the study were tested for NL ratio, erythrocyte sedimentation rate ESR, mmhr, C-reactive protein hsCRP, mgL, platelet count PLTL and MPVFL. GADS scores calculated. Results There was a significant difference in ESR p  0.001 and CRP levels p  0.002 in patients with high GADS scores compared to those with low GADS scores .In all patients, the mean GADS score was 24.77  11.00, and GADS scores were positively correlated with ESR and CRP levels. In our binary logistic regression analysis of age, sex, time, NL ratio, PLTL, MPV and ESR for identifying risk factors for severe acne vulgaris, the model explained 25.7 of high GADS scores. A high CRP level was identified as a risk factor for having a high GADS score. Conclusion In our study, we evaluated acne patients because it affects many age groups, is common, and sometimes causes extensive inflammation.

 Objective In this study, we investigated whether the Neutrophil Lymphosite NL ratio, mean platelet volume MPV value, GADS The global acne rating system score and other inflammatory parameters are related in acne vulgaris patients. Methods One-hundred acne patients, aged between 1840 years, who treated at the Karaman Training and Research Hospital Dermatology Polyclinic between January and March 2022 were included in the study. Age, sex, duration of disease, medications and additional systemic diseases were recorded. Acne patients included in the study were tested for NL ratio, erythrocyte sedimentation rate ESR, mmhr, C-reactive protein hsCRP, mgL, platelet count PLTL and MPVFL. GADS scores calculated. Results There was a significant difference in ESR p  0.001 and CRP levels p  0.002 in patients with high GADS scores compared to those with low GADS scores .In all patients, the mean GADS score was 24.77  11.00, and GADS scores were positively correlated with ESR and CRP levels. In our binary logistic regression analysis of age, sex, time, NL ratio, PLTL, MPV and ESR for identifying risk factors for severe acne vulgaris, the model explained 25.7 of high GADS scores. A high CRP level was identified as a risk factor for having a high GADS score. Conclusion In our study, we evaluated acne patients because it affects many age groups, is common, and sometimes causes extensive inflammation.

 Objective In this study, we investigated whether the Neutrophil Lymphosite NL ratio, mean platelet volume MPV value, GADS The global acne rating system score and other inflammatory parameters are related in acne vulgaris patients. Methods One-hundred acne patients, aged between 1840 years, who treated at the Karaman Training and Research Hospital Dermatology Polyclinic between January and March 2022 were included in the study. Age, sex, duration of disease, medications and additional systemic diseases were recorded. Acne patients included in the study were tested for NL ratio, erythrocyte sedimentation rate ESR, mmhr, C-reactive protein hsCRP, mgL, platelet count PLTL and MPVFL. GADS scores calculated. Results There was a significant difference in ESR p  0.001 and CRP levels p  0.002 in patients with high GADS scores compared to those with low GADS scores .In all patients, the mean GADS score was 24.77  11.00, and GADS scores were positively correlated with ESR and CRP levels. In our binary logistic regression analysis of age, sex, time, NL ratio, PLTL, MPV and ESR for identifying risk factors for severe acne vulgaris, the model explained 25.7 of high GADS scores. A high CRP level was identified as a risk factor for having a high GADS score. Conclusion In our study, we evaluated acne patients because it affects many age groups, is common, and sometimes causes extensive inflammation.

 Objective In this study, we investigated whether the Neutrophil Lymphosite NL ratio, mean platelet volume MPV value, GADS The global acne rating system score and other inflammatory parameters are related in acne vulgaris patients. Methods One-hundred acne patients, aged between 1840 years, who treated at the Karaman Training and Research Hospital Dermatology Polyclinic between January and March 2022 were included in the study. Age, sex, duration of disease, medications and additional systemic diseases were recorded. Acne patients included in the study were tested for NL ratio, erythrocyte sedimentation rate ESR, mmhr, C-reactive protein hsCRP, mgL, platelet count PLTL and MPVFL. GADS scores calculated. Results There was a significant difference in ESR p  0.001 and CRP levels p  0.002 in patients with high GADS scores compared to those with low GADS scores .In all patients, the mean GADS score was 24.77  11.00, and GADS scores were positively correlated with ESR and CRP levels. In our binary logistic regression analysis of age, sex, time, NL ratio, PLTL, MPV and ESR for identifying risk factors for severe acne vulgaris, the model explained 25.7 of high GADS scores. A high CRP level was identified as a risk factor for having a high GADS score. Conclusion In our study, we evaluated acne patients because it affects many age groups, is common, and sometimes causes extensive inflammation.

Makale detayları

Investigation of the Relationship between Clinical Severity of Acne and Inflammatory Parameters in Patients with Acne Vulgaris

Yazarlar:

Hanife Merve Akça | Kevser Tuncer Kara

Yayıncı:

Ondokuz Mayıs University

Ana Başlıklar:

Health Care Administration

Dergi:

Deneysel ve Klinik Tıp Dergisi Vol.40 Issue 2, pp.205-210

Belge Tipi:

Makale

Yayın Tarihi:

7/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001293694

pISSN:

1309-4483

acne severity

inflammatory parameters

inflammatory diseases

acne vulgaris

Sayı

Makale detayları

Investigation of the Relationship between Clinical Severity of Acne and Inflammatory Parameters in Patients with Acne Vulgaris

Yazarlar: Hanife Merve Akça | Kevser Tuncer Kara

Yayıncı: Ondokuz Mayıs University

Ana Başlıklar: Health Care Administration

Dergi: Deneysel ve Klinik Tıp Dergisi Vol.40 Issue 2, pp.205-210

Belge Tipi: Makale

Yayın Tarihi: 7/2023

Belge Dili: İngilizce

Document ID (Org No.): 2001293694

pISSN: 1309-4483

acne severity

inflammatory parameters

inflammatory diseases

acne vulgaris

Sayı

Yazarlar:

Hanife Merve Akça | Kevser Tuncer Kara

Yayıncı:

Ondokuz Mayıs University

Ana Başlıklar:

Health Care Administration

Dergi:

Deneysel ve Klinik Tıp Dergisi Vol.40 Issue 2, pp.205-210

Belge Tipi:

Makale

Yayın Tarihi:

7/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001293694

pISSN:

1309-4483