Effects of different percentages of body weight-supported treadmill training in Parkinson's disease: a double-blind randomized controlled trial

Tuğba ATAN; Özden Özyemişci TAŞKIRAN; Ayşe Bora TOKÇAER; Gülçin Kaymak KARATAŞ; Asli Karakuş ÇALIŞKAN; Belgin KARAOĞLAN

Makale detayları

Effects of different percentages of body weight-supported treadmill training in Parkinson's disease: a double-blind randomized controlled trial

Yazarlar:

Tuğba ATAN | Özden Özyemişci TAŞKIRAN | Ayşe Bora TOKÇAER | Gülçin Kaymak KARATAŞ | Asli Karakuş ÇALIŞKAN | Belgin KARAOĞLAN

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 2019 Vol.49 Issue 4, pp.999-1007

Belge Tipi:

Makale

Yayın Tarihi:

7/2019

Belge Dili:

İngilizce

Document ID (Org No.):

2000749955

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144

Özet:

 

Background/aim: Body weight-supported treadmill training (BWSTT) might have greater effects than conventional treadmill training (TT) in neurological diseases such as Parkinson's disease (PD). The aim of this study was to evaluate the effects of different percentages of BWSTT on gait, balance, quality of life, and fatigue in PD.Materials and methods: Thirty-five patients with moderate to advanced PD were randomized into three BWSTT groups according to the supported percentage of body weight: 0% BWSTT (control group; unsupported TT), 10% BWSTT, or 20% BWSTT. Five patients were excluded due to early discharge and 30 patients completed BWSTT sessions lasting 30 min, 5 days a week, for 6 weeks during their inpatient rehabilitation stay. The primary outcome was 6-min walk distance (6MWD). Secondary outcomes were Unified Parkinson's Disease Rating Scale (UPDRS), Berg Balance Scale (BBS), Nottingham Health Profile (NHP), Fatigue Impact Scale, and Fatigue Severity Scale scores. Measurements were performed before and after the training. Results: The unsupported TT group demonstrated no significant improvement in the outcome measures after a 6-week training except for BBS and NHP emotional subscores. Moreover, the NHP pain subscore increased in the unsupported TT group after training. The 10%  and  20%  supported  BWSTT  groups  demonstrated  significant  improvements  in  6MWD  (P  =  0.004  and  P  <  0.001,  respectively),  UPDRS - motor score (P = 0.012 and P = 0.005, respectively), NHP pain subscore (P = 0.003 and P = 0.002, respectively), and fatigue (P = 0.005 for both) after training. The 20% BWSTT provided the highest improvement in balance among the three groups (P < 0.001) and greater relief of fatigue than 10% BWSTT (P = 0.002).Conclusion:  Six  weeks  of  BWSTT  improved  walking  distance  and  balance  ability,  relieved  fatigue,  and  additionally  reduced  pain  in  patients with moderate to advanced PD.

Makale detayları

Effects of different percentages of body weight-supported treadmill training in Parkinson's disease: a double-blind randomized controlled trial

Yazarlar: Tuğba ATAN | Özden Özyemişci TAŞKIRAN | Ayşe Bora TOKÇAER | Gülçin Kaymak KARATAŞ | Asli Karakuş ÇALIŞKAN | Belgin KARAOĞLAN

Yayıncı: TUBITAK

Dergi: Turkish Journal of Medical Sciences 2019 Vol.49 Issue 4, pp.999-1007

Belge Tipi: Makale

Yayın Tarihi: 7/2019

Belge Dili: İngilizce

Document ID (Org No.): 2000749955

Sıklık: İki Aylık

eISSN: 1303-6165

pISSN: 1300-0144

Sayı

Yazarlar:

Tuğba ATAN | Özden Özyemişci TAŞKIRAN | Ayşe Bora TOKÇAER | Gülçin Kaymak KARATAŞ | Asli Karakuş ÇALIŞKAN | Belgin KARAOĞLAN

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 2019 Vol.49 Issue 4, pp.999-1007

Belge Tipi:

Makale

Yayın Tarihi:

7/2019

Belge Dili:

İngilizce

Document ID (Org No.):

2000749955

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144