Investigation on presence of major gene for body weight, feed intake and feed efficiency using a segregation analyses in a mice population

Burak KARACAÖREN; İssam MOSLEM

doi:https://doi.org/10.33988/auvfd.445947

Makale detayları

Investigation on presence of major gene for body weight, feed intake and feed efficiency using a segregation analyses in a mice population

Yazarlar:

Burak KARACAÖREN | İssam MOSLEM

Ana Başlıklar:

Hayvancılık

Dergi:

Ankara Üniversitesi Veteriner Fakültesi Dergisi 2019 Vol.66 Issue 4, pp.325-330

Belge Tipi:

Makale

Yayın Tarihi:

9/2019

Belge Dili:

İngilizce

Document ID (Org No.):

2000849568

DOI:

https://doi.org/10.33988/auvfd.445947

Özet:

 


Recent developments in molecular genetics and statistics have
allowed the identification and use of major genes to explain the genetic
variation. In this context, segregation analysis is a fast, reliable and
inexpensive method that uses only phenotype and pedigree information. The aim
of this study was to examine whether body weight, feed intake, and feed
efficiency in a mouse population are directed by major gene in addition to
polygenic and major gene effects by segregation analysis. For this purpose,
previously collected dataset was used (n= 661). In this study, genetic
variance, error variance, major gene variance, additive and dominant gene
effects were estimated by segregation analyses. Dominant variance (1.04) was
found to be smaller than the additive genetic variance (7.32) for body weight.
Polygenic and major gene heritability predicted as 0.29 (± 0.63) and 0.81 (±
0.98) for body weight, 0.35 (± 0.63) and 0.96 (± 0.98) for feed intake and 0.52
(± 0.63) and 0.81 (± 0.98) for feed efficiency respectively. Existence of major
gene was determined by examining the highest probability density regions.
Although the major gene has been identified for body weight and feed intake,
this result is not confirmed by the Mendelian transmission probabilities.


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Makale detayları

Investigation on presence of major gene for body weight, feed intake and feed efficiency using a segregation analyses in a mice population

Yazarlar: Burak KARACAÖREN | İssam MOSLEM

Ana Başlıklar: Hayvancılık

Dergi: Ankara Üniversitesi Veteriner Fakültesi Dergisi 2019 Vol.66 Issue 4, pp.325-330

Belge Tipi: Makale

Yayın Tarihi: 9/2019

Belge Dili: İngilizce

Document ID (Org No.): 2000849568

DOI: https://doi.org/10.33988/auvfd.445947

Sayı

Yazarlar:

Burak KARACAÖREN | İssam MOSLEM

Ana Başlıklar:

Hayvancılık

Dergi:

Ankara Üniversitesi Veteriner Fakültesi Dergisi 2019 Vol.66 Issue 4, pp.325-330

Belge Tipi:

Makale

Yayın Tarihi:

9/2019

Belge Dili:

İngilizce

Document ID (Org No.):

2000849568

DOI:

https://doi.org/10.33988/auvfd.445947