Comparison of nailfold capillaroscopy findings in COVID-19 survivors with and without rheumatic disease: a case-control study

Hüseyin Kaplan; Gizem Cengiz; Senem Şaş; Hasan Kara

Makale detayları

Comparison of nailfold capillaroscopy findings in COVID-19 survivors with and without rheumatic disease: a case-control study

Yazarlar:

Hüseyin Kaplan | Gizem Cengiz | Senem Şaş | Hasan Kara

Yayıncı:

Cukurova University

Ana Başlıklar:

Romatoloji ve Artrit

Dergi:

Cukurova Medical Journal Vol.49 Issue 1, pp.71-80

Belge Tipi:

Makale

Yayın Tarihi:

3/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001314673

pISSN:

2602-3032

Anahtar kelimeler:

Özet:

 Purpose: The aim of this study was to evaluate the nailfold capillaroscopy NFC findings of patients with rheumatic disease and healthy controls HCs who survived coronavirus disease 2019 COVID-19. Materials and Methods: This study included patients with axial spondyloarthritis axSpA, psoriatic arthritis PsA, and rheumatoid arthritis RA who recovered from COVID-19 and HCs. NFC was performed for all participants. NFC findings of the three groups patients with COVID-19 group 1, HCs with COVID-19 group 2, and HCs without COVID-19 group 3 were compared. Results: A total of 142 individuals group 1, n  42; group 2, n  50; group 3, n  50 were included in the study. Hospitalization and oxygen therapy were more common in group 1 than in group 2. The median time from a severe acute respiratory syndrome coronavirus 2 SARS-CoV-2-positive real-time polymerase chain reaction RT-PCR test to NFC was 10.3 6.324.4 weeks in group 1 and 17.1 6.144.9 weeks in group 2. All NFC findings did not differ among the groups except for capillary ramifications, which were higher in group 1 than in groups 2 and 3. Underlying rheumatic disease was the only predictor that was significantly associated with capillary ramifications. Conclusion: The NFC findings of COVID-19 survivors with and without rheumatic disease were substantially similar to those of HCs who did not have COVID-19. Capillary ramifications may result from an underlying rheumatic disease in patients with axSpA, PsA, and RA.

 Purpose: The aim of this study was to evaluate the nailfold capillaroscopy NFC findings of patients with rheumatic disease and healthy controls HCs who survived coronavirus disease 2019 COVID-19. Materials and Methods: This study included patients with axial spondyloarthritis axSpA, psoriatic arthritis PsA, and rheumatoid arthritis RA who recovered from COVID-19 and HCs. NFC was performed for all participants. NFC findings of the three groups patients with COVID-19 group 1, HCs with COVID-19 group 2, and HCs without COVID-19 group 3 were compared. Results: A total of 142 individuals group 1, n  42; group 2, n  50; group 3, n  50 were included in the study. Hospitalization and oxygen therapy were more common in group 1 than in group 2. The median time from a severe acute respiratory syndrome coronavirus 2 SARS-CoV-2-positive real-time polymerase chain reaction RT-PCR test to NFC was 10.3 6.324.4 weeks in group 1 and 17.1 6.144.9 weeks in group 2. All NFC findings did not differ among the groups except for capillary ramifications, which were higher in group 1 than in groups 2 and 3. Underlying rheumatic disease was the only predictor that was significantly associated with capillary ramifications. Conclusion: The NFC findings of COVID-19 survivors with and without rheumatic disease were substantially similar to those of HCs who did not have COVID-19. Capillary ramifications may result from an underlying rheumatic disease in patients with axSpA, PsA, and RA.

 Purpose: The aim of this study was to evaluate the nailfold capillaroscopy NFC findings of patients with rheumatic disease and healthy controls HCs who survived coronavirus disease 2019 COVID-19. Materials and Methods: This study included patients with axial spondyloarthritis axSpA, psoriatic arthritis PsA, and rheumatoid arthritis RA who recovered from COVID-19 and HCs. NFC was performed for all participants. NFC findings of the three groups patients with COVID-19 group 1, HCs with COVID-19 group 2, and HCs without COVID-19 group 3 were compared. Results: A total of 142 individuals group 1, n  42; group 2, n  50; group 3, n  50 were included in the study. Hospitalization and oxygen therapy were more common in group 1 than in group 2. The median time from a severe acute respiratory syndrome coronavirus 2 SARS-CoV-2-positive real-time polymerase chain reaction RT-PCR test to NFC was 10.3 6.324.4 weeks in group 1 and 17.1 6.144.9 weeks in group 2. All NFC findings did not differ among the groups except for capillary ramifications, which were higher in group 1 than in groups 2 and 3. Underlying rheumatic disease was the only predictor that was significantly associated with capillary ramifications. Conclusion: The NFC findings of COVID-19 survivors with and without rheumatic disease were substantially similar to those of HCs who did not have COVID-19. Capillary ramifications may result from an underlying rheumatic disease in patients with axSpA, PsA, and RA.

 Amaç: Bu çalışmanın amacı koronavirüs hastalığı 2019 COVİD-19 sonrası hayatta kalan romatizmal hastalığı olan hastaların ve sağlıklı kontrollerin tırnak dibi kapilleroskopisi bulgularını değerlendirmektir. Gereç ve Yöntem: Bu çalışmaya, COVİD-19dan sonra iyileşen aksiyal spondiloartrit akSpA, psoriatik artrit PsA ve romatoid artrit RA hastaları ve sağlıklı kontroller dâhil edildi. Tüm katılımcılara tırnak dibi kapilleroskopisi uygulandı. Üç grubun COVID-19 geçiren romatizmal hastalar grup 1, COVİD-19 geçiren sağlıklı kontroller grup 2 ve COVİD-19 geçirmeyen sağlıklı kontroller grup 3 tırnak dibi kapilleroskopi bulguları karşılaştırıldı. Bulgular: Çalışmaya grup 1de 42, grup 2de 50 ve grup 3te 50 olmak üzere toplam 142 kişi dâhil edildi. Hastaneye yatış ve oksijen tedavisi oranları grup 1de grup 2ye göre daha sıktı. Pozitif bir şiddetli akut solunum sendromu koronavirüs-2 SARS-CoV-2-real-time polimeraz zincir reaksiyonu RT-PCR testinden tırnak dibi kapilleroskopisine kadar geçen ortalama süre grup 1de 10,3 6,324,4 hafta ve grup 2de 17,1 6,144,9 haftaydı. Grup 1de grup 2 ve 3e göre daha yüksek oranda olan kapiller dallanmalar dışında, tüm kapilleroskopik bulgular gruplar arasında farklılık göstermedi. Altta yatan romatizmal hastalık kapiller dallanmalarla anlamlı şekilde ilişkili olan tek prediktördü. Sonuç: Romatizmal hastalığı olan ve olmayan, COVİD-19dan sağ kurtulanların tırnak dibi kapilleroskopi bulguları, sağlıklı kontrollerle büyük ölçüde benzerdi. AkSpA, PsA ve RA hastalarında kapiller dallanmalar altta yatan romatizmal hastalığın bir sonucu olabilir.

Makale detayları

Comparison of nailfold capillaroscopy findings in COVID-19 survivors with and without rheumatic disease: a case-control study

Yazarlar:

Hüseyin Kaplan | Gizem Cengiz | Senem Şaş | Hasan Kara

Yayıncı:

Cukurova University

Ana Başlıklar:

Romatoloji ve Artrit

Dergi:

Cukurova Medical Journal Vol.49 Issue 1, pp.71-80

Belge Tipi:

Makale

Yayın Tarihi:

3/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001314673

pISSN:

2602-3032

Capillaries

COVID-19

microcirculation

nailfold capillaroscopyKapiller damarlar

COVİD-19

mikrosirkülasyon

tırnak dibi kapilleroskopisi

Sayı

Makale detayları

Yazarlar: Hüseyin Kaplan | Gizem Cengiz | Senem Şaş | Hasan Kara

Yayıncı: Cukurova University

Ana Başlıklar: Romatoloji ve Artrit

Dergi: Cukurova Medical Journal Vol.49 Issue 1, pp.71-80

Belge Tipi: Makale

Yayın Tarihi: 3/2024

Belge Dili: İngilizce

Document ID (Org No.): 2001314673

pISSN: 2602-3032

Sayı

Yazarlar:

Hüseyin Kaplan | Gizem Cengiz | Senem Şaş | Hasan Kara

Yayıncı:

Cukurova University

Ana Başlıklar:

Romatoloji ve Artrit

Dergi:

Cukurova Medical Journal Vol.49 Issue 1, pp.71-80

Belge Tipi:

Makale

Yayın Tarihi:

3/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001314673

pISSN:

2602-3032