Effects of Lead and Selenium Interaction on Acetylcholinesterase Activity in Brain and Accumulation of Metal in Tissues of Oreochromis niloticus (L., 1758)

Gülsemin ŞEN; Sahire KARAYTUĞ

doi:https://doi.org/10.28978/nesciences.328857

Makale detayları

Effects of Lead and Selenium Interaction on Acetylcholinesterase Activity in Brain and Accumulation of Metal in Tissues of Oreochromis niloticus (L., 1758)

Yazarlar:

Gülsemin ŞEN | Sahire KARAYTUĞ

Yayıncı:

Cemal TURAN

Ana Başlıklar:

Ekoloji

Dergi:

Natural and Engineering Sciences 2017 Vol.2 Issue 2, pp.21-32

Belge Tipi:

Makale

Yayın Tarihi:

6/2017

Belge Dili:

İngilizce

Document ID (Org No.):

2000610074

Sıklık:

Üç Aylık

eISSN:

2458-8989

pISSN:

2458-8989

DOI:

https://doi.org/10.28978/nesciences.328857

Özet:

 


The potential accumulation of lead in different tissues of Oreochromis niloticus and the effects of selenium in AChE inhibition caused by lead in brain were investigated. Juvenile O. niloticus samples were exposed to combination of 1 mg L-1 and 2 mg L-1 lead and 1mg L-1 lead+2mg L-1 selenium and 2mg L-1 lead+4mg L-1 selenium for 1, 7 and 15 days respectively. The accumulation of lead in gill, brain, liver and muscle tissues was analyzed by Inductively Coupled Plasma Mass Spectrometry (ICP-MS) as well as brain acetylcholinesterase (AChE, E.C.3.1.1.7) enzyme activity was also analyzed by spectrophotometric method. No mortality was observed during lead exposure in relation to time period and exposed concentrations. Lead accumulation was occurred in all tissues in relation to time. Maximum lead accumulation occurred in brain tissue, followed by the liver, gills and muscle tissues in relation to time period. Selenium caused a decrease on accumulation of lead in tissues (all selenium mixtures in muscle tissue on the first day, 1mg L-1 Pb+2mg L-1 selenium in gill tissue on the seventh day, in liver tissue on the seventh day except 2mg L-1 Pb+4mg L-1 selenium mixtures) at the end of each of all three test periods. Inhibition of AChE activity was caused by the highest concentration and by the short-term effect of lead. Such effect of lead was eliminated by selenium mixture. Lead and selenium mixture were resulted an increase in activity on 15th day at the highest concentration. Selenium led to decrease in the accumulation of lead in the tissues and caused to improvement in the loss of AChE activity.

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Makale detayları

Effects of Lead and Selenium Interaction on Acetylcholinesterase Activity in Brain and Accumulation of Metal in Tissues of Oreochromis niloticus (L., 1758)

Yazarlar: Gülsemin ŞEN | Sahire KARAYTUĞ

Yayıncı: Cemal TURAN

Ana Başlıklar: Ekoloji

Dergi: Natural and Engineering Sciences 2017 Vol.2 Issue 2, pp.21-32

Belge Tipi: Makale

Yayın Tarihi: 6/2017

Belge Dili: İngilizce

Document ID (Org No.): 2000610074

Sıklık: Üç Aylık

eISSN: 2458-8989

pISSN: 2458-8989

DOI: https://doi.org/10.28978/nesciences.328857

Sayı

Yazarlar:

Gülsemin ŞEN | Sahire KARAYTUĞ

Yayıncı:

Cemal TURAN

Ana Başlıklar:

Ekoloji

Dergi:

Natural and Engineering Sciences 2017 Vol.2 Issue 2, pp.21-32

Belge Tipi:

Makale

Yayın Tarihi:

6/2017

Belge Dili:

İngilizce

Document ID (Org No.):

2000610074

Sıklık:

Üç Aylık

eISSN:

2458-8989

pISSN:

2458-8989

DOI:

https://doi.org/10.28978/nesciences.328857