Investigation of hereditary cholesterol deficiency (CD) in Holstein Cattle at the state farms in Türkiye

Ceyhan Özbeyaz

Makale detayları

Investigation of hereditary cholesterol deficiency (CD) in Holstein Cattle at the state farms in Türkiye

Yazarlar:

Ceyhan Özbeyaz

Yayıncı:

Ankara University

Ana Başlıklar:

Animal Science | Genetics and Biostatistics

Dergi:

Ankara Üniversitesi Veteriner Fakültesi Dergisi Vol.71 Issue 3, pp.321-328

Belge Tipi:

Makale

Yayın Tarihi:

10/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001322319

pISSN:

1300-0861

Anahtar kelimeler:

Özet:

 Türkiye is exposed to international animal and semen movements. For this reason, Türkiye is very affected by diseases and hereditary disorders. State Farms is a state organization that raises and distributes breeding cattle. This study was aimed at investigating the presence and distribution of mutant alleles causing cholesterol deficiency CD disorder in Holstein cattle on state farms. For this purpose, blood and sperm samples were collected from 466 Holstein cattle. The real-time PCR method was used for genotyping. A total of seven cattle were found to be heterozygous. The frequency of the mutant allele was determined to be 0.75. The kinship of four cattle carrying the mutant allele with Mauglin Storm, the bull in which this disease was first detected, was determined. The presence of cattle carrying the mutant allele in Türkiye is quite low compared to other countries. The Apolipoprotein-B APOB mutant allele was found at low frequencies and detected for the first time at the State Farms in Türkiye. Therefore, it is necessary to develop control programs by screening other Holstein herds.

 Türkiye is exposed to international animal and semen movements. For this reason, Türkiye is very affected by diseases and hereditary disorders. State Farms is a state organization that raises and distributes breeding cattle. This study was aimed at investigating the presence and distribution of mutant alleles causing cholesterol deficiency CD disorder in Holstein cattle on state farms. For this purpose, blood and sperm samples were collected from 466 Holstein cattle. The real-time PCR method was used for genotyping. A total of seven cattle were found to be heterozygous. The frequency of the mutant allele was determined to be 0.75. The kinship of four cattle carrying the mutant allele with Mauglin Storm, the bull in which this disease was first detected, was determined. The presence of cattle carrying the mutant allele in Türkiye is quite low compared to other countries. The Apolipoprotein-B APOB mutant allele was found at low frequencies and detected for the first time at the State Farms in Türkiye. Therefore, it is necessary to develop control programs by screening other Holstein herds.

 Türkiye is exposed to international animal and semen movements. For this reason, Türkiye is very affected by diseases and hereditary disorders. State Farms is a state organization that raises and distributes breeding cattle. This study was aimed at investigating the presence and distribution of mutant alleles causing cholesterol deficiency CD disorder in Holstein cattle on state farms. For this purpose, blood and sperm samples were collected from 466 Holstein cattle. The real-time PCR method was used for genotyping. A total of seven cattle were found to be heterozygous. The frequency of the mutant allele was determined to be 0.75. The kinship of four cattle carrying the mutant allele with Mauglin Storm, the bull in which this disease was first detected, was determined. The presence of cattle carrying the mutant allele in Türkiye is quite low compared to other countries. The Apolipoprotein-B APOB mutant allele was found at low frequencies and detected for the first time at the State Farms in Türkiye. Therefore, it is necessary to develop control programs by screening other Holstein herds.

 Türkiye is exposed to international animal and semen movements. For this reason, Türkiye is very affected by diseases and hereditary disorders. State Farms is a state organization that raises and distributes breeding cattle. This study was aimed at investigating the presence and distribution of mutant alleles causing cholesterol deficiency CD disorder in Holstein cattle on state farms. For this purpose, blood and sperm samples were collected from 466 Holstein cattle. The real-time PCR method was used for genotyping. A total of seven cattle were found to be heterozygous. The frequency of the mutant allele was determined to be 0.75. The kinship of four cattle carrying the mutant allele with Mauglin Storm, the bull in which this disease was first detected, was determined. The presence of cattle carrying the mutant allele in Türkiye is quite low compared to other countries. The Apolipoprotein-B APOB mutant allele was found at low frequencies and detected for the first time at the State Farms in Türkiye. Therefore, it is necessary to develop control programs by screening other Holstein herds.

Makale detayları

Investigation of hereditary cholesterol deficiency (CD) in Holstein Cattle at the state farms in Türkiye

Yazarlar:

Ceyhan Özbeyaz

Yayıncı:

Ankara University

Ana Başlıklar:

Animal Science | Genetics and Biostatistics

Dergi:

Ankara Üniversitesi Veteriner Fakültesi Dergisi Vol.71 Issue 3, pp.321-328

Belge Tipi:

Makale

Yayın Tarihi:

10/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001322319

pISSN:

1300-0861

Apolipoprotein-B

Cattle

Cholestrol Deficiency

Holstein

Mutation

Sayı

Makale detayları

Investigation of hereditary cholesterol deficiency (CD) in Holstein Cattle at the state farms in Türkiye

Yazarlar: Ceyhan Özbeyaz

Yayıncı: Ankara University

Ana Başlıklar: Animal Science | Genetics and Biostatistics

Dergi: Ankara Üniversitesi Veteriner Fakültesi Dergisi Vol.71 Issue 3, pp.321-328

Belge Tipi: Makale

Yayın Tarihi: 10/2024

Belge Dili: İngilizce

Document ID (Org No.): 2001322319

pISSN: 1300-0861

Apolipoprotein-B

Cattle

Cholestrol Deficiency

Holstein

Mutation

Sayı

Yazarlar:

Ceyhan Özbeyaz

Yayıncı:

Ankara University

Ana Başlıklar:

Animal Science | Genetics and Biostatistics

Dergi:

Ankara Üniversitesi Veteriner Fakültesi Dergisi Vol.71 Issue 3, pp.321-328

Belge Tipi:

Makale

Yayın Tarihi:

10/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001322319

pISSN:

1300-0861