Cognitive Assessment in Patients with Acute COVID-19: A Cross-Sectional Study

Yusuf Koçak; Asuman Çelikbilek; Burc Esra Sahin; Duygu Zorlu; Gökmen Zararsız

Makale detayları

Cognitive Assessment in Patients with Acute COVID-19: A Cross-Sectional Study

Yazarlar:

Yusuf Koçak | Asuman Çelikbilek | Burc Esra Sahin | Duygu Zorlu | Gökmen Zararsız

Yayıncı:

Kirsehir Ahi Evran University

Ana Başlıklar:

Klinik Tıp Bilimleri

Dergi:

Ahi Evran Tıp Dergisi Vol.7 Issue 3, pp.364-370

Belge Tipi:

Makale

Yayın Tarihi:

12/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001300288

pISSN:

2619-9203

Anahtar kelimeler:

Özet:

 Purpose: Many reports have revealed a high percentage of patients suffering from cognitive impairment due to COVID-19. We investigated cognitive functions using the Montreal Cognitive Assessment MoCA in mild COVID-19 patients compared with non-COVID-19 patients within 5 days after the initial respiratory symptoms of infection. Materials and Methods: 113 patients with mild COVID-19 and 109 age- and sex-matched controls were enrolled in this prospective cross-sectional study. Cognitive functions were evaluated using the MoCA. Results: We found that the MoCA scores were significantly lower in the COVID-19 patients than in the controls P0.001. Compared to the controls, we found point deficits within some MoCA items such as visuospatial P0.001, memory P0.017, and attention P0.048 domains. In the multivariate model, female sex 2.06 1.024.16, P0.044, low education level 150.05 5.1643.90, P0.001, high fasting blood glucose level 0.98 0.961.00, P0.043, and the presence of COVID-19 24.24 9.5261.72, P0.001 were independently associated with cognitive impairment OR, 95 CI. Conclusion: We detected cognitive dysfunction, involving the visuospatial domain, memory, and attention, during the acute phase in patients with mild COVID-19.

 Purpose: Many reports have revealed a high percentage of patients suffering from cognitive impairment due to COVID-19. We investigated cognitive functions using the Montreal Cognitive Assessment MoCA in mild COVID-19 patients compared with non-COVID-19 patients within 5 days after the initial respiratory symptoms of infection. Materials and Methods: 113 patients with mild COVID-19 and 109 age- and sex-matched controls were enrolled in this prospective cross-sectional study. Cognitive functions were evaluated using the MoCA. Results: We found that the MoCA scores were significantly lower in the COVID-19 patients than in the controls P0.001. Compared to the controls, we found point deficits within some MoCA items such as visuospatial P0.001, memory P0.017, and attention P0.048 domains. In the multivariate model, female sex 2.06 1.024.16, P0.044, low education level 150.05 5.1643.90, P0.001, high fasting blood glucose level 0.98 0.961.00, P0.043, and the presence of COVID-19 24.24 9.5261.72, P0.001 were independently associated with cognitive impairment OR, 95 CI. Conclusion: We detected cognitive dysfunction, involving the visuospatial domain, memory, and attention, during the acute phase in patients with mild COVID-19.

 Purpose: Many reports have revealed a high percentage of patients suffering from cognitive impairment due to COVID-19. We investigated cognitive functions using the Montreal Cognitive Assessment MoCA in mild COVID-19 patients compared with non-COVID-19 patients within 5 days after the initial respiratory symptoms of infection. Materials and Methods: 113 patients with mild COVID-19 and 109 age- and sex-matched controls were enrolled in this prospective cross-sectional study. Cognitive functions were evaluated using the MoCA. Results: We found that the MoCA scores were significantly lower in the COVID-19 patients than in the controls P0.001. Compared to the controls, we found point deficits within some MoCA items such as visuospatial P0.001, memory P0.017, and attention P0.048 domains. In the multivariate model, female sex 2.06 1.024.16, P0.044, low education level 150.05 5.1643.90, P0.001, high fasting blood glucose level 0.98 0.961.00, P0.043, and the presence of COVID-19 24.24 9.5261.72, P0.001 were independently associated with cognitive impairment OR, 95 CI. Conclusion: We detected cognitive dysfunction, involving the visuospatial domain, memory, and attention, during the acute phase in patients with mild COVID-19.

 Amaç: COVID-19a bağlı kognitif bozukluk daha önce yapılan çalışmalarda yüksek oranda bildirilmiştir. Enfeksiyonun ilk solunum semptomlarından sonraki 5 gün içinde, hafif COVID-19 hastalarında, COVID-19 olmayan hastalara kıyasla, Montreal Bilişsel Değerlendirmesini MoCA kullanarak bilişsel işlevleri araştırıldı. Araçlar ve Yöntem: Bu prospektif kesitsel çalışmaya hafif COVID-19lu 113 hasta ve yaş ve cinsiyet olarak eşleştirilmiş 109 kontrol alındı. Bilişsel işlevler, MoCA kullanılarak değerlendirildi. Bulgular: MoCA skorlarının COVID-19 hastalarında kontrollere göre anlamlı derecede düşük olduğunu bulduk P0.001. Kontrollerle karşılaştırıldığında, görsel uzamsal P0.001, bellek P0.017 ve dikkat P0.048 alanları gibi bazı MoCA öğelerinde puan kayıpları bulduk. Çok değişkenli modelde kadın cinsiyet 2.06 1.024.16, P0.044, düşük eğitim düzeyi 15.05 5.1643.90, P0.001, yüksek açlık kan şekeri düzeyi 0.98 0.961.00, P0.043 ve COVID-19 24.24 9.5261.72, P0.001 varlığı bağımsız olarak kognitif bozuklukla ilişkiliyidi OR, 95 CI. Sonuç: Hafif COVID-19lu hastalarda akut faz sırasında görsel uzamsal, bellek ve dikkat alanlarında bilişsel işlev bozukluğu tespit edildi.

Makale detayları

Cognitive Assessment in Patients with Acute COVID-19: A Cross-Sectional Study

Yazarlar:

Yusuf Koçak | Asuman Çelikbilek | Burc Esra Sahin | Duygu Zorlu | Gökmen Zararsız

Yayıncı:

Kirsehir Ahi Evran University

Ana Başlıklar:

Klinik Tıp Bilimleri

Dergi:

Ahi Evran Tıp Dergisi Vol.7 Issue 3, pp.364-370

Belge Tipi:

Makale

Yayın Tarihi:

12/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001300288

pISSN:

2619-9203

COVID-19

cognition

cognitive assessment

montreal cognitive assessment

pandemicCOVID-19

biliş

bilişsel değerlendirme

montreal bilişsel değerlendirme

salgın

Sayı

Makale detayları

Yazarlar: Yusuf Koçak | Asuman Çelikbilek | Burc Esra Sahin | Duygu Zorlu | Gökmen Zararsız

Yayıncı: Kirsehir Ahi Evran University

Ana Başlıklar: Klinik Tıp Bilimleri

Dergi: Ahi Evran Tıp Dergisi Vol.7 Issue 3, pp.364-370

Belge Tipi: Makale

Yayın Tarihi: 12/2023

Belge Dili: İngilizce

Document ID (Org No.): 2001300288

pISSN: 2619-9203

Sayı

Yazarlar:

Yusuf Koçak | Asuman Çelikbilek | Burc Esra Sahin | Duygu Zorlu | Gökmen Zararsız

Yayıncı:

Kirsehir Ahi Evran University

Ana Başlıklar:

Klinik Tıp Bilimleri

Dergi:

Ahi Evran Tıp Dergisi Vol.7 Issue 3, pp.364-370

Belge Tipi:

Makale

Yayın Tarihi:

12/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001300288

pISSN:

2619-9203