Efficacy of entecavir treatment among chronic hepatitis B nucleos(t)ide-naïve and -experienced patients

Kadir Çağatay BİÇER; Alpay ARI; Vecdi Evren GENÇ; Sibel ÖZSU CAYMAZ; Meltem AVCI; Fatma BAL

Makale detayları

Efficacy of entecavir treatment among chronic hepatitis B nucleos(t)ide-naïve and -experienced patients

Yazarlar:

Kadir Çağatay BİÇER | Alpay ARI | Vecdi Evren GENÇ | Sibel ÖZSU CAYMAZ | Meltem AVCI | Fatma BAL

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 2015 Vol.45 Issue 1, pp.99-104

Belge Tipi:

Makale

Yayın Tarihi:

3/2015

Belge Dili:

Türkçe

Document ID (Org No.):

2000752872

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144

Anahtar kelimeler:

Özet:

 

To evaluate the efficacy of entecavir (ETV) among chronic hepatitis B (CHB) nucleos(t)ide-naïve and -experienced patients in clinical practice.  Materials and methods: In this retrospective study 85 CHB patients who had been receiving ETV and who attended our clinic since 2007 were included. Fifty patients were nucleos(t)ide analogue (NA)-naïve. Factors including sex, positive HBeAg, baseline HBV DNA level, baseline alanine aminotransferase level, and prior lamivudine (LAM) resistance were evaluated in terms of their predictive role in treatment response, which was defined as a serum HBV DNA decrease of.

 

To evaluate the efficacy of entecavir (ETV) among chronic hepatitis B (CHB) nucleos(t)ide-naïve and -experienced patients in clinical practice.  Materials and methods: In this retrospective study 85 CHB patients who had been receiving ETV and who attended our clinic since 2007 were included. Fifty patients were nucleos(t)ide analogue (NA)-naïve. Factors including sex, positive HBeAg, baseline HBV DNA level, baseline alanine aminotransferase level, and prior lamivudine (LAM) resistance were evaluated in terms of their predictive role in treatment response, which was defined as a serum HBV DNA decrease of.

Makale detayları

Efficacy of entecavir treatment among chronic hepatitis B nucleos(t)ide-naïve and -experienced patients

Yazarlar:

Kadir Çağatay BİÇER | Alpay ARI | Vecdi Evren GENÇ | Sibel ÖZSU CAYMAZ | Meltem AVCI | Fatma BAL

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 2015 Vol.45 Issue 1, pp.99-104

Belge Tipi:

Makale

Yayın Tarihi:

3/2015

Belge Dili:

Türkçe

Document ID (Org No.):

2000752872

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144

Chronic hepatitis B virus infection

entecavir

efficacy

predictive factors

viral response

lamivudine resistance

Sayı

Makale detayları

Efficacy of entecavir treatment among chronic hepatitis B nucleos(t)ide-naïve and -experienced patients

Yazarlar: Kadir Çağatay BİÇER | Alpay ARI | Vecdi Evren GENÇ | Sibel ÖZSU CAYMAZ | Meltem AVCI | Fatma BAL

Yayıncı: TUBITAK

Dergi: Turkish Journal of Medical Sciences 2015 Vol.45 Issue 1, pp.99-104

Belge Tipi: Makale

Yayın Tarihi: 3/2015

Belge Dili: Türkçe

Document ID (Org No.): 2000752872

Sıklık: İki Aylık

eISSN: 1303-6165

pISSN: 1300-0144

Chronic hepatitis B virus infection

entecavir

efficacy

predictive factors

viral response

lamivudine resistance

Sayı

Yazarlar:

Kadir Çağatay BİÇER | Alpay ARI | Vecdi Evren GENÇ | Sibel ÖZSU CAYMAZ | Meltem AVCI | Fatma BAL

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 2015 Vol.45 Issue 1, pp.99-104

Belge Tipi:

Makale

Yayın Tarihi:

3/2015

Belge Dili:

Türkçe

Document ID (Org No.):

2000752872

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144