Comparison of Preoperative Hematological Parameters Among Benign, Premalignant, and Malignant Uterine Pathologies

Selçuk Atalay; Tuğba Karadeniz Atalay; Cem Dane; Nihal Çallıoğlu

Makale detayları

Comparison of Preoperative Hematological Parameters Among Benign, Premalignant, and Malignant Uterine Pathologies

Yazarlar:

Selçuk Atalay | Tuğba Karadeniz Atalay | Cem Dane | Nihal Çallıoğlu

Yayıncı:

Ordu University

Ana Başlıklar:

Clinical Sciences (Other)

Dergi:

Middle Black Sea Journal of Health Science Vol.11 Issue 3, pp.179-189

Belge Tipi:

Makale

Yayın Tarihi:

8/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001357757

pISSN:

2149-7796

Anahtar kelimeler:

Özet:

 Objective: Based on the influence of uterine inflammation on the development of malignancy, we aimed to determine the difference in the preoperative parameters in benign uterine pathology of haematological parameters analysed and to evaluate the association with premalignant and malignant. Method: Our study included 343 patients who underwent surgery for benign, premalignant and malignant pathologies of the uterus between January 2007 and August 2014 at Education and Research Hospital. Of the total 343 operated patients, 228 66.5 were diagnosed with uterine myoma. Among the 58 patients in the endometrial hyperplasia group, 33 56.9 were diagnosed with simple hyperplasia without atypia, 7 12.1 with simple atypical hyperplasia, 7 12.1 with complex hyperplasia without atypia, and 11 18,9 with complex atypical hyperplasia. In the endometrial cancer group, which consisted of 57 patients, 52 91.2 were diagnosed with endometrioid-type endometrial adenocarcinoma, 3 5.2 with carcinosarcoma, 1 1.7 with a mixed type serous papillary  endometrioid and 1 1.7 with endometrial stromal sarcoma. All patients achieved hemograms in the preoperative period. Results: In our study group, the endometrial carcinoma and hyperplasia neutrophil count Neu , neutrophil percentage Neu , haemoglobin Hb, haematocrit Hct and mean corpuscular volume MCV were significantly higher than those in the control group. Lymphocyte ratio and red cell distribution width RDW terms were significantly lower than those in the control group. Conclusion: We think that routine haematological parameters such as neutrophil count, neutrophil percentage, MCV and RDW which are inexpensive, repeatable, and easily accessible from complete blood count panels, may be useful in predicting benign and malignant diseases of the endometrium.

 Objective: Based on the influence of uterine inflammation on the development of malignancy, we aimed to determine the difference in the preoperative parameters in benign uterine pathology of haematological parameters analysed and to evaluate the association with premalignant and malignant. Method: Our study included 343 patients who underwent surgery for benign, premalignant and malignant pathologies of the uterus between January 2007 and August 2014 at Education and Research Hospital. Of the total 343 operated patients, 228 66.5 were diagnosed with uterine myoma. Among the 58 patients in the endometrial hyperplasia group, 33 56.9 were diagnosed with simple hyperplasia without atypia, 7 12.1 with simple atypical hyperplasia, 7 12.1 with complex hyperplasia without atypia, and 11 18,9 with complex atypical hyperplasia. In the endometrial cancer group, which consisted of 57 patients, 52 91.2 were diagnosed with endometrioid-type endometrial adenocarcinoma, 3 5.2 with carcinosarcoma, 1 1.7 with a mixed type serous papillary  endometrioid and 1 1.7 with endometrial stromal sarcoma. All patients achieved hemograms in the preoperative period. Results: In our study group, the endometrial carcinoma and hyperplasia neutrophil count Neu , neutrophil percentage Neu , haemoglobin Hb, haematocrit Hct and mean corpuscular volume MCV were significantly higher than those in the control group. Lymphocyte ratio and red cell distribution width RDW terms were significantly lower than those in the control group. Conclusion: We think that routine haematological parameters such as neutrophil count, neutrophil percentage, MCV and RDW which are inexpensive, repeatable, and easily accessible from complete blood count panels, may be useful in predicting benign and malignant diseases of the endometrium.

 Objective: Based on the influence of uterine inflammation on the development of malignancy, we aimed to determine the difference in the preoperative parameters in benign uterine pathology of haematological parameters analysed and to evaluate the association with premalignant and malignant. Method: Our study included 343 patients who underwent surgery for benign, premalignant and malignant pathologies of the uterus between January 2007 and August 2014 at Education and Research Hospital. Of the total 343 operated patients, 228 66.5 were diagnosed with uterine myoma. Among the 58 patients in the endometrial hyperplasia group, 33 56.9 were diagnosed with simple hyperplasia without atypia, 7 12.1 with simple atypical hyperplasia, 7 12.1 with complex hyperplasia without atypia, and 11 18,9 with complex atypical hyperplasia. In the endometrial cancer group, which consisted of 57 patients, 52 91.2 were diagnosed with endometrioid-type endometrial adenocarcinoma, 3 5.2 with carcinosarcoma, 1 1.7 with a mixed type serous papillary  endometrioid and 1 1.7 with endometrial stromal sarcoma. All patients achieved hemograms in the preoperative period. Results: In our study group, the endometrial carcinoma and hyperplasia neutrophil count Neu , neutrophil percentage Neu , haemoglobin Hb, haematocrit Hct and mean corpuscular volume MCV were significantly higher than those in the control group. Lymphocyte ratio and red cell distribution width RDW terms were significantly lower than those in the control group. Conclusion: We think that routine haematological parameters such as neutrophil count, neutrophil percentage, MCV and RDW which are inexpensive, repeatable, and easily accessible from complete blood count panels, may be useful in predicting benign and malignant diseases of the endometrium.

 Objective: Based on the influence of uterine inflammation on the development of malignancy, we aimed to determine the difference in the preoperative parameters in benign uterine pathology of haematological parameters analysed and to evaluate the association with premalignant and malignant. Method: Our study included 343 patients who underwent surgery for benign, premalignant and malignant pathologies of the uterus between January 2007 and August 2014 at Education and Research Hospital. Of the total 343 operated patients, 228 66.5 were diagnosed with uterine myoma. Among the 58 patients in the endometrial hyperplasia group, 33 56.9 were diagnosed with simple hyperplasia without atypia, 7 12.1 with simple atypical hyperplasia, 7 12.1 with complex hyperplasia without atypia, and 11 18,9 with complex atypical hyperplasia. In the endometrial cancer group, which consisted of 57 patients, 52 91.2 were diagnosed with endometrioid-type endometrial adenocarcinoma, 3 5.2 with carcinosarcoma, 1 1.7 with a mixed type serous papillary  endometrioid and 1 1.7 with endometrial stromal sarcoma. All patients achieved hemograms in the preoperative period. Results: In our study group, the endometrial carcinoma and hyperplasia neutrophil count Neu , neutrophil percentage Neu , haemoglobin Hb, haematocrit Hct and mean corpuscular volume MCV were significantly higher than those in the control group. Lymphocyte ratio and red cell distribution width RDW terms were significantly lower than those in the control group. Conclusion: We think that routine haematological parameters such as neutrophil count, neutrophil percentage, MCV and RDW which are inexpensive, repeatable, and easily accessible from complete blood count panels, may be useful in predicting benign and malignant diseases of the endometrium.

Makale detayları

Comparison of Preoperative Hematological Parameters Among Benign, Premalignant, and Malignant Uterine Pathologies

Yazarlar:

Selçuk Atalay | Tuğba Karadeniz Atalay | Cem Dane | Nihal Çallıoğlu

Yayıncı:

Ordu University

Ana Başlıklar:

Clinical Sciences (Other)

Dergi:

Middle Black Sea Journal of Health Science Vol.11 Issue 3, pp.179-189

Belge Tipi:

Makale

Yayın Tarihi:

8/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001357757

pISSN:

2149-7796

Lymphocytes

platelets

neutrophils

endometrial neoplasms

thrombocytosis

Sayı

Makale detayları

Comparison of Preoperative Hematological Parameters Among Benign, Premalignant, and Malignant Uterine Pathologies

Yazarlar: Selçuk Atalay | Tuğba Karadeniz Atalay | Cem Dane | Nihal Çallıoğlu

Yayıncı: Ordu University

Ana Başlıklar: Clinical Sciences (Other)

Dergi: Middle Black Sea Journal of Health Science Vol.11 Issue 3, pp.179-189

Belge Tipi: Makale

Yayın Tarihi: 8/2025

Belge Dili: İngilizce

Document ID (Org No.): 2001357757

pISSN: 2149-7796

Lymphocytes

platelets

neutrophils

endometrial neoplasms

thrombocytosis

Sayı

Yazarlar:

Selçuk Atalay | Tuğba Karadeniz Atalay | Cem Dane | Nihal Çallıoğlu

Yayıncı:

Ordu University

Ana Başlıklar:

Clinical Sciences (Other)

Dergi:

Middle Black Sea Journal of Health Science Vol.11 Issue 3, pp.179-189

Belge Tipi:

Makale

Yayın Tarihi:

8/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001357757

pISSN:

2149-7796