Incidental findings of brain magnetic resonance imaging in patients with treatment-resistant depression

Olga Bayar Kapıcı; Yaşar Kapıcı; Mehmet Şirik; Dilek Örüm

Makale detayları

Incidental findings of brain magnetic resonance imaging in patients with treatment-resistant depression

Yazarlar:

Olga Bayar Kapıcı | Yaşar Kapıcı | Mehmet Şirik | Dilek Örüm

Yayıncı:

Adıyaman University

Ana Başlıklar:

Merkezi Sinir Sistemi

Dergi:

Adıyaman Üniversitesi Sağlık Bilimleri Dergisi Vol.11 Issue 1, pp.27-36

Belge Tipi:

Makale

Yayın Tarihi:

4/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001344928

pISSN:

2458-9179

Anahtar kelimeler:

Özet:

 Aim: In this study, incidental findings of brain magnetic resonance imaging MRI of patients diagnosed with treatment-resistant depression TRD were compared with healthy controls HC. Materials and Methods: The study included 68 patients with TRD 42 females, 26 males and 72 HC 35 females, 37 males. Global assessment scale GAS was administered. Results: In the TRD group, those with general cerebral atrophy were found to have significantly lower global assessment scale GAS scores p0.001. In the TRD group, those with cavum veli interpositi CVI were found to have significantly lower GAS scores p0.001. In the TRD group, when the effect of age was controlled, a significant correlation was found between the GAS score and the duration of the disorder r-0.400; p0.001. Conclusion: CVI, a neurodevelopmental abnormality, has been shown to be more common in patients diagnosed with TRD.

 Aim: In this study, incidental findings of brain magnetic resonance imaging MRI of patients diagnosed with treatment-resistant depression TRD were compared with healthy controls HC. Materials and Methods: The study included 68 patients with TRD 42 females, 26 males and 72 HC 35 females, 37 males. Global assessment scale GAS was administered. Results: In the TRD group, those with general cerebral atrophy were found to have significantly lower global assessment scale GAS scores p0.001. In the TRD group, those with cavum veli interpositi CVI were found to have significantly lower GAS scores p0.001. In the TRD group, when the effect of age was controlled, a significant correlation was found between the GAS score and the duration of the disorder r-0.400; p0.001. Conclusion: CVI, a neurodevelopmental abnormality, has been shown to be more common in patients diagnosed with TRD.

 Aim: In this study, incidental findings of brain magnetic resonance imaging MRI of patients diagnosed with treatment-resistant depression TRD were compared with healthy controls HC. Materials and Methods: The study included 68 patients with TRD 42 females, 26 males and 72 HC 35 females, 37 males. Global assessment scale GAS was administered. Results: In the TRD group, those with general cerebral atrophy were found to have significantly lower global assessment scale GAS scores p0.001. In the TRD group, those with cavum veli interpositi CVI were found to have significantly lower GAS scores p0.001. In the TRD group, when the effect of age was controlled, a significant correlation was found between the GAS score and the duration of the disorder r-0.400; p0.001. Conclusion: CVI, a neurodevelopmental abnormality, has been shown to be more common in patients diagnosed with TRD.

 Amaç: Bu çalışmada, tedaviye dirençli depresyon TDD tanılı hastaların beyin manyetik rezonans görüntüleme MRGnin tesadüfi bulguları sağlıklı kontrollerle SK karşılaştırıldı. Gereç ve Yöntem: Çalışmaya TDD tanılı 68 hasta 42 kadın, 26 erkek ve 72 SK 35 kadın, 37 erkek dahil edildi. Global değerlendirme ölçeği GDÖ uygulandı. Bulgular: TDD grubunda, genel serebral atrofisi olanların global değerlendirme ölçeği GDÖ skorlarının anlamlı derecede düşük olduğu bulundu p0,001. TDD grubunda, kavum veli interpositi KVİ saptananların GDÖ skorlarının anlamlı derecede düşük olduğu bulundu p0,001. TDD grubunda, yaşın etkisi kontrol edildiğinde, GDÖ skoru ile bozukluk süresi arasında anlamlı bir korelasyon bulundu r-0,400; p0,001. Sonuç: Nörogelişimsel bir anormallik olan KVİnin TDD tanılı hastalarda daha yaygın olduğu gösterilmiştir.

Makale detayları

Incidental findings of brain magnetic resonance imaging in patients with treatment-resistant depression

Yazarlar:

Olga Bayar Kapıcı | Yaşar Kapıcı | Mehmet Şirik | Dilek Örüm

Yayıncı:

Adıyaman University

Ana Başlıklar:

Merkezi Sinir Sistemi

Dergi:

Adıyaman Üniversitesi Sağlık Bilimleri Dergisi Vol.11 Issue 1, pp.27-36

Belge Tipi:

Makale

Yayın Tarihi:

4/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001344928

pISSN:

2458-9179

magnetic resonance imaging

Treatment-resistant major depressive disorder

Incidental findingTedaviye dirençli majör depresif bozukluk

Manyetik rezonans görüntüleme

Tesadüfi bulgu

Sayı

Makale detayları

Incidental findings of brain magnetic resonance imaging in patients with treatment-resistant depression

Yazarlar: Olga Bayar Kapıcı | Yaşar Kapıcı | Mehmet Şirik | Dilek Örüm

Yayıncı: Adıyaman University

Ana Başlıklar: Merkezi Sinir Sistemi

Dergi: Adıyaman Üniversitesi Sağlık Bilimleri Dergisi Vol.11 Issue 1, pp.27-36

Belge Tipi: Makale

Yayın Tarihi: 4/2025

Belge Dili: İngilizce

Document ID (Org No.): 2001344928

pISSN: 2458-9179

magnetic resonance imaging

Treatment-resistant major depressive disorder

Incidental findingTedaviye dirençli majör depresif bozukluk

Manyetik rezonans görüntüleme

Tesadüfi bulgu

Sayı

Yazarlar:

Olga Bayar Kapıcı | Yaşar Kapıcı | Mehmet Şirik | Dilek Örüm

Yayıncı:

Adıyaman University

Ana Başlıklar:

Merkezi Sinir Sistemi

Dergi:

Adıyaman Üniversitesi Sağlık Bilimleri Dergisi Vol.11 Issue 1, pp.27-36

Belge Tipi:

Makale

Yayın Tarihi:

4/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001344928

pISSN:

2458-9179