FABRICATION AND CONTROLLING MORPHOLOGY OF POLYETHYLENE OXIDE/SODIUM ALGINATE BEADS AND/OR FIBERS: EFFECT OF VISCOSITY AND CONDUCTIVITY IN ELECTROSPINNING

Tuğba Eren Böncü

Makale detayları

FABRICATION AND CONTROLLING MORPHOLOGY OF POLYETHYLENE OXIDE/SODIUM ALGINATE BEADS AND/OR FIBERS: EFFECT OF VISCOSITY AND CONDUCTIVITY IN ELECTROSPINNING

Yazarlar:

Tuğba Eren Böncü

Yayıncı:

Ankara University

Ana Başlıklar:

Eczacılık ve İlaç Bilimleri

Dergi:

Ankara Üniversitesi Eczacılık Fakültesi Dergisi Vol.47 Issue 2, pp.420-429

Belge Tipi:

Makale

Yayın Tarihi:

5/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001282820

pISSN:

1015-3918

Anahtar kelimeler:

Özet:

 Objective: The aim of the study is to determine the viscosity and conductivity of PEONaAlg polymer solutions, to formulate PEONaAlg beads, bead-on-string fibers and fibers via electrospinning, and to perform advanced morphological characterization studies on them. Material and Method: Effect of PEO and NaAlg concentration and ratio of them on spinnability, viscosity and conductivity of solutions, and also on the morphological properties of PEONaAlg electrospun fibers, and beads length, width and aspect ratio of beads, number of beads and bead area were investigated. Result and Discussion: As a result, electrospun materials were produced using PEONaAlg beads andor fibers, which are valuable for medical and biological applications such as tissue engineering, wound dressing, drug delivery system. Viscosity and conductivity of solutions, and morphological properties of the obtained materials were found to be affected by PEO and NaAlg concentration and the ratio of them. Spinnability was improved thanks to the increase in conductivity in the presence of PEO. The lower viscosity and conductivity resulted in the production of beads that were generally smaller and greater in number in the material and having higher area. The morphological properties of PEONaAlg electrospun materials can be modified by controlling the parameters examined in the study.

 Objective: The aim of the study is to determine the viscosity and conductivity of PEONaAlg polymer solutions, to formulate PEONaAlg beads, bead-on-string fibers and fibers via electrospinning, and to perform advanced morphological characterization studies on them. Material and Method: Effect of PEO and NaAlg concentration and ratio of them on spinnability, viscosity and conductivity of solutions, and also on the morphological properties of PEONaAlg electrospun fibers, and beads length, width and aspect ratio of beads, number of beads and bead area were investigated. Result and Discussion: As a result, electrospun materials were produced using PEONaAlg beads andor fibers, which are valuable for medical and biological applications such as tissue engineering, wound dressing, drug delivery system. Viscosity and conductivity of solutions, and morphological properties of the obtained materials were found to be affected by PEO and NaAlg concentration and the ratio of them. Spinnability was improved thanks to the increase in conductivity in the presence of PEO. The lower viscosity and conductivity resulted in the production of beads that were generally smaller and greater in number in the material and having higher area. The morphological properties of PEONaAlg electrospun materials can be modified by controlling the parameters examined in the study.

 Objective: The aim of the study is to determine the viscosity and conductivity of PEONaAlg polymer solutions, to formulate PEONaAlg beads, bead-on-string fibers and fibers via electrospinning, and to perform advanced morphological characterization studies on them. Material and Method: Effect of PEO and NaAlg concentration and ratio of them on spinnability, viscosity and conductivity of solutions, and also on the morphological properties of PEONaAlg electrospun fibers, and beads length, width and aspect ratio of beads, number of beads and bead area were investigated. Result and Discussion: As a result, electrospun materials were produced using PEONaAlg beads andor fibers, which are valuable for medical and biological applications such as tissue engineering, wound dressing, drug delivery system. Viscosity and conductivity of solutions, and morphological properties of the obtained materials were found to be affected by PEO and NaAlg concentration and the ratio of them. Spinnability was improved thanks to the increase in conductivity in the presence of PEO. The lower viscosity and conductivity resulted in the production of beads that were generally smaller and greater in number in the material and having higher area. The morphological properties of PEONaAlg electrospun materials can be modified by controlling the parameters examined in the study.

 Amaç: Çalışmanın amacı, PEONaAlg polimer çözeltilerinin viskozite ve iletkenliklerini belirlemek, PEONaAlg boncukları, boncuk-iplik lifleri ve lifleri elektroeğirme yöntemiyle formüle etmek ve bunlar üzerinde ileri morfolojik karakterizasyon çalışmaları yapmaktır. Gereç ve Yöntem: PEO ve NaAlg derişiminin ve oranlarının çözeltilerin eğrilebilirliği, viskozitesi ve iletkenliği ve ayrıca PEONaAlg elektroeğrilmiş liflerin ve boncukların morfolojik özellikleri boncukların uzunluğu, genişliği ve en boy oranı, boncuk sayısı üzerindeki etkisi incelenmiştir. Sonuç ve Tartışma: Sonuç olarak, doku mühendisliği, yara örtüsü, ilaç taşıyıcı sistem gibi tıbbi ve biyolojik uygulamalar için değerli olan PEONaAlg boncuklar veveya lifler elektroeğirme yöntemiyle üretilmiştir. Çözeltilerin viskozite ve iletkenliği ile üretilen materyalin morfolojik özelliklerinin PEO ve NaAlg derişiminden ve oranlarından etkilendiği bulunmuştur. PEO varlığında iletkenlikteki artış sayesinde eğrilebilirlik iyileştirilmiştir. Daha düşük viskozite ve iletkenlik, genellikle daha küçük, daha fazla sayıda ve daha büyük alana sahip boncukların üretilmesine neden olmuştur. PEONaAlg elektroeğrilmiş materyallerin morfolojik özellikleri, çalışmada incelenen parametreler kontrol edilerek değiştirilebilir.

Makale detayları

FABRICATION AND CONTROLLING MORPHOLOGY OF POLYETHYLENE OXIDE/SODIUM ALGINATE BEADS AND/OR FIBERS: EFFECT OF VISCOSITY AND CONDUCTIVITY IN ELECTROSPINNING

Yazarlar:

Tuğba Eren Böncü

Yayıncı:

Ankara University

Ana Başlıklar:

Eczacılık ve İlaç Bilimleri

Dergi:

Ankara Üniversitesi Eczacılık Fakültesi Dergisi Vol.47 Issue 2, pp.420-429

Belge Tipi:

Makale

Yayın Tarihi:

5/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001282820

pISSN:

1015-3918

Conductivity

electrospinning

electrospun beads

polyethylene oxide (PEO)/sodium alginate (NaAlg)

viscosity

Elektrik iletkenliği

elektroeğirme

elektroeğrilmiş boncuklar

polietilen oksit(PEO)/sodyum aljinat (NaAlj)

viskozite

Sayı

Makale detayları

Yazarlar: Tuğba Eren Böncü

Yayıncı: Ankara University

Ana Başlıklar: Eczacılık ve İlaç Bilimleri

Dergi: Ankara Üniversitesi Eczacılık Fakültesi Dergisi Vol.47 Issue 2, pp.420-429

Belge Tipi: Makale

Yayın Tarihi: 5/2023

Belge Dili: İngilizce

Document ID (Org No.): 2001282820

pISSN: 1015-3918

Sayı

Yazarlar:

Tuğba Eren Böncü

Yayıncı:

Ankara University

Ana Başlıklar:

Eczacılık ve İlaç Bilimleri

Dergi:

Ankara Üniversitesi Eczacılık Fakültesi Dergisi Vol.47 Issue 2, pp.420-429

Belge Tipi:

Makale

Yayın Tarihi:

5/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001282820

pISSN:

1015-3918