Bioactive Compounds of Myrtle Berrys’ Ultrasound-Assisted Extraction Conditions Optimized by Response Surface Methodology

Tugba Dursun Capar

Makale detayları

Bioactive Compounds of Myrtle Berrys’ Ultrasound-Assisted Extraction Conditions Optimized by Response Surface Methodology

Yazarlar:

Tugba Dursun Capar

Yayıncı:

Cukurova University

Ana Başlıklar:

Gıda Mühendisliği

Dergi:

Çukurova Tarım ve Gıda Bilimleri Dergisi Vol.38 Issue 1, pp.1-13

Belge Tipi:

Makale

Yayın Tarihi:

6/2023

Belge Dili:

Türkçe

Document ID (Org No.):

2001294654

pISSN:

2636-7874

Anahtar kelimeler:

Özet:

 Phytochemicals, such as phenolic compounds, are of great interest due to their health beneficial antioxidant properties and possible protection against inflammation, cardiovascular diseases and certain types of cancer. The bioactive compounds in myrtle berries have shown a potentially positive effect on human health. In this study, bioactive compounds of myrtle berries were optimized by using ultrasound-assisted extraction USE technique. The optimal extraction conditions in term of total phenolic content TPC and total antioxidant activity AA were determined using Response Surface Methodology RSM BoxBehnken design. The influence of extraction parameters including, ultrasonication power, sonication time and solid-solvent ratio on TPC and AA were modeled by using a second-order regression equation. The highest desirability was observed with an ultrasonic power of 70, a solidsolvent ratio of 7 , and an extraction time of 15 min. Sonication power and solid-solvent ratio were the significant parameters for the extraction process p0.05. Under these optimized conditions, the predicted value for TPC and DPPH radical scavenging activity were 1.07 g GAE L extract, and 96.41 , whereas the observed experimental values were found as 1.164 g GAE L extract and 100.34 , respectively. These findings show that extraction of bioactive compounds from myrtle berries using USE technique consumes less solvent and time.

 Phytochemicals, such as phenolic compounds, are of great interest due to their health beneficial antioxidant properties and possible protection against inflammation, cardiovascular diseases and certain types of cancer. The bioactive compounds in myrtle berries have shown a potentially positive effect on human health. In this study, bioactive compounds of myrtle berries were optimized by using ultrasound-assisted extraction USE technique. The optimal extraction conditions in term of total phenolic content TPC and total antioxidant activity AA were determined using Response Surface Methodology RSM BoxBehnken design. The influence of extraction parameters including, ultrasonication power, sonication time and solid-solvent ratio on TPC and AA were modeled by using a second-order regression equation. The highest desirability was observed with an ultrasonic power of 70, a solidsolvent ratio of 7 , and an extraction time of 15 min. Sonication power and solid-solvent ratio were the significant parameters for the extraction process p0.05. Under these optimized conditions, the predicted value for TPC and DPPH radical scavenging activity were 1.07 g GAE L extract, and 96.41 , whereas the observed experimental values were found as 1.164 g GAE L extract and 100.34 , respectively. These findings show that extraction of bioactive compounds from myrtle berries using USE technique consumes less solvent and time.

 Phytochemicals, such as phenolic compounds, are of great interest due to their health beneficial antioxidant properties and possible protection against inflammation, cardiovascular diseases and certain types of cancer. The bioactive compounds in myrtle berries have shown a potentially positive effect on human health. In this study, bioactive compounds of myrtle berries were optimized by using ultrasound-assisted extraction USE technique. The optimal extraction conditions in term of total phenolic content TPC and total antioxidant activity AA were determined using Response Surface Methodology RSM BoxBehnken design. The influence of extraction parameters including, ultrasonication power, sonication time and solid-solvent ratio on TPC and AA were modeled by using a second-order regression equation. The highest desirability was observed with an ultrasonic power of 70, a solidsolvent ratio of 7 , and an extraction time of 15 min. Sonication power and solid-solvent ratio were the significant parameters for the extraction process p0.05. Under these optimized conditions, the predicted value for TPC and DPPH radical scavenging activity were 1.07 g GAE L extract, and 96.41 , whereas the observed experimental values were found as 1.164 g GAE L extract and 100.34 , respectively. These findings show that extraction of bioactive compounds from myrtle berries using USE technique consumes less solvent and time.

 Fenolik bileşikler gibi bazı fitokimyasallar, antioksidan özellikleri nedeni ile iltihaplanma, kalp damar hastalıkları ve belirli kanser türlerine karşı olası koruma sağladıklarından büyük ilgi görmektedir. Murt meyvesi Myrtus communis L. içerdiği biyoaktif bileşiklerden dolayı insan sağlığı üzerinde potansiyel pozitif etki göstermektedir. Bu çalışmada, murt meyvesinin biyoaktif bileşikleri ultrasonik-destekli ekstraksiyon USE yöntemi ile optimize edilmiştir. Murt meyvesi ekstraktlarının toplam fenolik madde içeriği TFM ve antioksidan aktivite AA açısından optimal ekstraksiyon koşulları, Yanıt Yüzey Yöntemi RSM Box-Behnken deney tasarımı kullanılarak belirlenmiştir. Ultrasonikasyon gücü, ultrasonikasyon süresi ve katı-sıvı oranı gibi ekstraksiyon parametrelerinin TFM ve AA üzerindeki etkisi, ikinci dereceden bir regresyon denklemi kullanılarak modellenmiştir. Optimum USE koşulları 70 W sonikasyon gücü, 15 dakika sonikasyon süresi ve  7 katı-sıvı oranında elde edilmiştir. Sonikasyon gücü ve katı-sıvı oranı TFM ve AA ekstraksiyon işleminde istatistiksel olarak önemli p0.05 bulunmuştur. Optimum koşullar altında TFM ve AA sırası ile 1.164 g GAEL ve  100.34 olarak tahminlenirken, bu değerler deneysel olarak 1.07 g GAEL ve  96.41 olarak bulunmuştur. Elde edilen sonuçlar, deneysel tasarım ile murt meyvesinden biyoaktif bileşiklerin USE yöntemi ile ekstraksiyonunun zaman ve çözgen açısından fayda sağladığını ortaya koymaktadır.

Makale detayları

Bioactive Compounds of Myrtle Berrys’ Ultrasound-Assisted Extraction Conditions Optimized by Response Surface Methodology

Yazarlar:

Tugba Dursun Capar

Yayıncı:

Cukurova University

Ana Başlıklar:

Gıda Mühendisliği

Dergi:

Çukurova Tarım ve Gıda Bilimleri Dergisi Vol.38 Issue 1, pp.1-13

Belge Tipi:

Makale

Yayın Tarihi:

6/2023

Belge Dili:

Türkçe

Document ID (Org No.):

2001294654

pISSN:

2636-7874

murt

biyoaktif bileşikler

ultrases-destekli ekstraksiyon

optimizasyon

Sayı

Makale detayları

Bioactive Compounds of Myrtle Berrys’ Ultrasound-Assisted Extraction Conditions Optimized by Response Surface Methodology

Yazarlar: Tugba Dursun Capar

Yayıncı: Cukurova University

Ana Başlıklar: Gıda Mühendisliği

Dergi: Çukurova Tarım ve Gıda Bilimleri Dergisi Vol.38 Issue 1, pp.1-13

Belge Tipi: Makale

Yayın Tarihi: 6/2023

Belge Dili: Türkçe

Document ID (Org No.): 2001294654

pISSN: 2636-7874

murt

biyoaktif bileşikler

ultrases-destekli ekstraksiyon

optimizasyon

Sayı

Yazarlar:

Tugba Dursun Capar

Yayıncı:

Cukurova University

Ana Başlıklar:

Gıda Mühendisliği

Dergi:

Çukurova Tarım ve Gıda Bilimleri Dergisi Vol.38 Issue 1, pp.1-13

Belge Tipi:

Makale

Yayın Tarihi:

6/2023

Belge Dili:

Türkçe

Document ID (Org No.):

2001294654

pISSN:

2636-7874