Effects of strontium ranilate and Hypericum perforatum extract on experimental colitis model in rats

Atilla KURT; Sinan SOYLU; Zeynep Deniz ŞAHİN INAL; Musa SERİN

doi:https://doi.org/10.7197/223.v40i37154.390415

Makale detayları

Effects of strontium ranilate and Hypericum perforatum extract on experimental colitis model in rats

Yazarlar:

Atilla KURT | Sinan SOYLU | Zeynep Deniz ŞAHİN INAL | Musa SERİN

Ana Başlıklar:

Sağlık teşvikleri

Dergi:

Cumhuriyet Medical Journal 2018 Vol.40 Issue 2, pp.194-200

Belge Tipi:

Makale

Yayın Tarihi:

6/2018

Belge Dili:

İngilizce

Document ID (Org No.):

2000922744

DOI:

https://doi.org/10.7197/223.v40i37154.390415

Özet:

 


Objective:
In this study, we aimed to compare the healing effect of strontium ranilate(SR)
and hypericum perfaratum (HPE) with the healing effect of prednisolone used in
the treatment of experimental colit in rats.


Material
and Method: 30 wistar albino rats were used in the study. Rats
were randomly assigned to 5 consecutive groups consisting of 5 rats. Group 1,
healthy rats, group 2 colitis but untreated rats. The rats in groups 3, 4, and
5 had colitis and received 160 mg / kg SR, 1mg/kg prednisolone and  HP extracts containing 0.3% hiperisine (250
uq / 300 mg) by oral gavage, respectively for seven days. At the end of the
seventh day, the colons of the rats were removed and histopathological
examination was performed. 


Results:
The histopathological results of the HPE group were statistically worst
including the control group. It was observed that the best results in the
treatment groups were SR group followed by prednisolone group, respectively.(P<0.05)


.

Makale detayları

Effects of strontium ranilate and Hypericum perforatum extract on experimental colitis model in rats

Yazarlar: Atilla KURT | Sinan SOYLU | Zeynep Deniz ŞAHİN INAL | Musa SERİN

Ana Başlıklar: Sağlık teşvikleri

Dergi: Cumhuriyet Medical Journal 2018 Vol.40 Issue 2, pp.194-200

Belge Tipi: Makale

Yayın Tarihi: 6/2018

Belge Dili: İngilizce

Document ID (Org No.): 2000922744

DOI: https://doi.org/10.7197/223.v40i37154.390415

Sayı

Yazarlar:

Atilla KURT | Sinan SOYLU | Zeynep Deniz ŞAHİN INAL | Musa SERİN

Ana Başlıklar:

Sağlık teşvikleri

Dergi:

Cumhuriyet Medical Journal 2018 Vol.40 Issue 2, pp.194-200

Belge Tipi:

Makale

Yayın Tarihi:

6/2018

Belge Dili:

İngilizce

Document ID (Org No.):

2000922744

DOI:

https://doi.org/10.7197/223.v40i37154.390415