Comparison of Clinical and Histopathologic Findings of Pathergy Test with Disposable/Sharp and Nondisposable/Blunt Needles in Behcet´s Disease

Ayşe Serap KARADAĞ; Gülfer AKBAY; Mehtap AYDIN

Makale detayları

Comparison of Clinical and Histopathologic Findings of Pathergy Test with Disposable/Sharp and Nondisposable/Blunt Needles in Behcet´s Disease

Yazarlar:

Ayşe Serap KARADAĞ | Gülfer AKBAY | Mehtap AYDIN

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 2009 Vol.39 Issue 1, pp.47-51

Belge Tipi:

Makale

Yayın Tarihi:

12/2008

Belge Dili:

Türkçe

Document ID (Org No.):

2000755586

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144

Anahtar kelimeler:

Özet:

 

Aim: The aim of this study was to determine whether using blunt instead of sharp needles presented any advantage and whether the histopathological interpretation prevailed over the clinical interpretation.   Materials and Methods: This study was performed on 60 Behçet´s disease (BD) patients and 20 control subjects. The pathergy test was applied to all subjects intradermally with sharp and blunt needles and the histopathology of each test result was studied.   Results: In the active period of BD (40 patients), positive test results were obtained in 34 (85.0%) patients using blunt needles and in 13 (32.5%) using sharp needles (P = 0.0001). In the active group, there was a significant difference in results when compared with the histopathologic findings (P < 0.05). In the remission period group (20 patients), positive results were obtained in 9 (45.0%) patients with blunt needles and in 2 (10.0%) with sharp needles (P = 0.013). In the remission group, there were no significant differences in results when compared with the histopathologic findings. In the control group patients, all blunt and sharp needle pathergy tests were negative.   Conclusions: This study has demonstrated that a higher positivity rate is obtained in pathergy tests using blunt needles when compared with sharp needles. We suggest that clinical interpretation of the pathergy test with blunt needles is adequate to determine activity of BD; histopathologic interpretation does not provide any extra advantages.

 

Aim: The aim of this study was to determine whether using blunt instead of sharp needles presented any advantage and whether the histopathological interpretation prevailed over the clinical interpretation.   Materials and Methods: This study was performed on 60 Behçet´s disease (BD) patients and 20 control subjects. The pathergy test was applied to all subjects intradermally with sharp and blunt needles and the histopathology of each test result was studied.   Results: In the active period of BD (40 patients), positive test results were obtained in 34 (85.0%) patients using blunt needles and in 13 (32.5%) using sharp needles (P = 0.0001). In the active group, there was a significant difference in results when compared with the histopathologic findings (P < 0.05). In the remission period group (20 patients), positive results were obtained in 9 (45.0%) patients with blunt needles and in 2 (10.0%) with sharp needles (P = 0.013). In the remission group, there were no significant differences in results when compared with the histopathologic findings. In the control group patients, all blunt and sharp needle pathergy tests were negative.   Conclusions: This study has demonstrated that a higher positivity rate is obtained in pathergy tests using blunt needles when compared with sharp needles. We suggest that clinical interpretation of the pathergy test with blunt needles is adequate to determine activity of BD; histopathologic interpretation does not provide any extra advantages.

Makale detayları

Comparison of Clinical and Histopathologic Findings of Pathergy Test with Disposable/Sharp and Nondisposable/Blunt Needles in Behcet´s Disease

Yazarlar: Ayşe Serap KARADAĞ | Gülfer AKBAY | Mehtap AYDIN

Yayıncı: TUBITAK

Dergi: Turkish Journal of Medical Sciences 2009 Vol.39 Issue 1, pp.47-51

Belge Tipi: Makale

Yayın Tarihi: 12/2008

Belge Dili: Türkçe

Document ID (Org No.): 2000755586

Sıklık: İki Aylık

eISSN: 1303-6165

pISSN: 1300-0144

Behçet´s disease

blunt needles

histopathological interpretation

pathergy test

sharp needles

Sayı

Yazarlar:

Ayşe Serap KARADAĞ | Gülfer AKBAY | Mehtap AYDIN

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 2009 Vol.39 Issue 1, pp.47-51

Belge Tipi:

Makale

Yayın Tarihi:

12/2008

Belge Dili:

Türkçe

Document ID (Org No.):

2000755586

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144